David Huang (ophthalmologist)

Huang completed his medical internship at Mercy Hospital in San Diego in 1994, before moving to the University of Southern California to complete his ophthalmology residency in 1997. Huang completed his cornea, external diseases, and refractive surgery fellowship at Emory University in 1998. Following this, he worked in the Cleveland Clinic until 2004 as an associative staff in refractive surgery, cornea, and biomedical engineering. Huang then took on a role as Associate Professor of Ophthalmology and Biomedical Engineering at USC and Medical Director of the Doheny Laser Vision Center until 2010.

David Huang is a board-certified ophthalmologist and currently the Director of Research and Associate Director of the Casey Eye Institute of the Oregon Health & Science University (OHSU). He is also the director of the Center for Ophthalmic Optics & Lasers,{{Cite web |title=Home |url=https://www.coollab.net/ |access-date=2025-01-19 |website=coollab |language=en}} a research group that works on novel OCT imaging and laser therapeutic technologies for clinical applications. He is the Wold Family Chair in Ophthalmologic Imaging and a professor of ophthalmology and biomedical engineering at the OHSU School of Medicine.{{Cite web |title=David Huang M.D., Ph.D. {{!}} Health care provider {{!}} OHSU |url=https://www.ohsu.edu/providers/david-huang-md-phd |access-date=2025-01-19 |website=www.ohsu.edu}}

Huang is an inventor and holds 44 U.S. patents{{Cite web |title=Dr. David Huang {{!}} Casey Eye Institute {{!}} OHSU |url=https://www.ohsu.edu/casey-eye-institute/meet-dr-david-huang |access-date=2025-01-19 |website=www.ohsu.edu}} in the areas of OCT, OCT angiography, laser therapeutics, tissue engineering, and smartphone eye screening.

Huang co-founded two companies.  GoCheck Kids provides smartphone apps that screen young children for potential vision and hearing problems.{{Cite web |date=2025-01-18 |title=David Huang {{!}} National Inventors Hall of Fame® Inductee |url=https://www.invent.org/inductees/david-huang |access-date=2025-01-19 |website=www.invent.org |language=en}}  Unfold Therapeutics, Inc. is developing a laser thermal conjunctivoplasty device¹⁷ to treat conjunctivochalasis, a common cause of eye irritation associated with aging.

Optical coherence tomography is an imaging technique that Huang co-invented in collaboration with Eric Swanson and Dr. James Fujimoto, his PhD advisor, resulting in the publication of the article 'Optical Coherence Tomography' in 1991 in Science. This publication focused on the imaging potential for very small structures, specifically the retina and coronary artery plaque, due to its micrometer depth resolution. OCT utilizes light to view subsurface structures in the body.{{Cite journal |last=Davis |first=Tinsley |date=Sep 26, 2023 |title=QnAs with James G. Fujimoto, David Huang, and Eric A. Swanson: Winners of the 2023 Lasker~DeBakey Clinical Medical Research Award |journal=Proc Natl Acad Sci USA |volume=120 |issue=39 |pages=e2313883120 |doi=10.1073/pnas.2313883120 |doi-access=free |pmid=37732757 |pmc=10523481 |bibcode=2023PNAS..12013883D }} This has led to its application in many different medical fields. Usage of OCT is now considered standard of care within the clinical specialties of ophthalmology{{Cite journal |last=Toth |first=Cynthia A. |date=2023-10-19 |title=Optical Coherence Tomography and Eye Care |url=https://doi.org/10.1056/nejmcibr2307733 |journal=New England Journal of Medicine |volume=389 |issue=16 |pages=1526–1529 |doi=10.1056/nejmcibr2307733 |pmid=37732605 |issn=0028-4793|url-access=subscription }} and cardiology{{Cite journal |last=Dauerman |first=Harold L. |date=2023-10-19 |title=Optical Coherence Tomography — Light and Truth |url=http://www.nejm.org/doi/10.1056/NEJMe2309710 |journal=New England Journal of Medicine |language=en |volume=389 |issue=16 |pages=1523–1525 |doi=10.1056/NEJMe2309710 |pmid=37851880 |issn=0028-4793|url-access=subscription }}

Since the invention of OCT, Huang has worked to help further develop the technology and its clinical applications. He has contributed to the extensions of OCT technology such as polarization-sensitive OCT,{{Cite journal |last1=Hee |first1=Michael R. |last2=Swanson |first2=Eric A. |last3=Fujimoto |first3=James G. |last4=Huang |first4=David |date=1992-06-01 |title=Polarization-sensitive low-coherence reflectometer for birefringence characterization and ranging |url=https://opg.optica.org/abstract.cfm?URI=josab-9-6-903 |journal=Journal of the Optical Society of America B |language=en |volume=9 |issue=6 |pages=903 |doi=10.1364/JOSAB.9.000903 |bibcode=1992JOSAB...9..903H |issn=0740-3224|url-access=subscription }} corneal and anterior segment OCT,{{Cite journal |last1=Goldsmith |first1=Jason A. |last2=Li |first2=Yan |last3=Chalita |first3=Maria Regina |last4=Westphal |first4=Volker |last5=Patil |first5=Chetan A. |last6=Rollins |first6=Andrew M. |last7=Izatt |first7=Joseph A. |last8=Huang |first8=David |date=Feb 2005 |title=Anterior Chamber Width Measurement by High-Speed Optical Coherence Tomography |journal=Ophthalmology |language=en |volume=112 |issue=2 |pages=238–244 |doi=10.1016/j.ophtha.2004.09.019 |pmc=1784115 |pmid=15691557}} Doppler OCT,{{Cite journal |last1=Wang |first1=Yimin |last2=Bower |first2=Bradley A. |last3=Izatt |first3=Joseph A. |last4=Tan |first4=Ou |last5=Huang |first5=David |date=2007 |title=In vivo total retinal blood flow measurement by Fourier domain Doppler optical coherence tomography |url=http://biomedicaloptics.spiedigitallibrary.org/article.aspx?doi=10.1117/1.2772871 |journal=Journal of Biomedical Optics |language=en |volume=12 |issue=4 |pages=041215 |doi=10.1117/1.2772871|pmid=17867804 |bibcode=2007JBO....12d1215W }} OCT angiography,{{Cite journal |last1=Jia |first1=Yali |last2=Tan |first2=Ou |last3=Tokayer |first3=Jason |last4=Potsaid |first4=Benjamin |last5=Wang |first5=Yimin |last6=Liu |first6=Jonathan J. |last7=Kraus |first7=Martin F. |last8=Subhash |first8=Hrebesh |last9=Fujimoto |first9=James G. |last10=Hornegger |first10=Joachim |last11=Huang |first11=David |date=2012-02-09 |title=Split-spectrum amplitude-decorrelation angiography with optical coherence tomography |journal=Optics Express |language=en |volume=20 |issue=4 |pages=4710–4725 |doi=10.1364/OE.20.004710 |pmc=3381646 |pmid=22418228|bibcode=2012OExpr..20.4710J }} and OCT optoretinography.{{Cite journal |last1=Chen |first1=Siyu |last2=Ni |first2=Shuibin |last3=Jiménez-Villar |first3=Alfonso |last4=Jian |first4=Yifan |last5=Jia |first5=Yali |last6=Huang |first6=David |date=2023-08-01 |title=Optical coherence tomography split-spectrum amplitude-decorrelation optoretinography |url=https://opg.optica.org/abstract.cfm?URI=ol-48-15-3921 |journal=Optics Letters |language=en |volume=48 |issue=15 |pages=3921–3924 |doi=10.1364/OL.492178 |pmid=37527083 |bibcode=2023OptL...48.3921C |issn=0146-9592|url-access=subscription }} His research group has applied these technologies to the diagnosis and management of retinal,{{Cite journal |last=Hee |first=Michael R. |date=1995-03-01 |title=Optical Coherence Tomography of the Human Retina |url=http://archopht.jamanetwork.com/article.aspx?doi=10.1001/archopht.1995.01100030081025 |journal=Archives of Ophthalmology |language=en |volume=113 |issue=3 |pages=325–332 |doi=10.1001/archopht.1995.01100030081025 |pmid=7887846 |issn=0003-9950|url-access=subscription }}{{Cite journal |last1=Jia |first1=Yali |last2=Bailey |first2=Steven T. |last3=Hwang |first3=Thomas S. |last4=McClintic |first4=Scott M. |last5=Gao |first5=Simon S. |last6=Pennesi |first6=Mark E. |last7=Flaxel |first7=Christina J. |last8=Lauer |first8=Andreas K. |last9=Wilson |first9=David J. |last10=Hornegger |first10=Joachim |last11=Fujimoto |first11=James G. |last12=Huang |first12=David |date=2015-04-20 |title=Quantitative optical coherence tomography angiography of vascular abnormalities in the living human eye |journal=Proceedings of the National Academy of Sciences of the United States of America |language=en |volume=112 |issue=18 |pages=E2395-402 |doi=10.1073/pnas.1500185112 |doi-access=free |pmc=4426471 |pmid=25897021|bibcode=2015PNAS..112E2395J }}{{Cite journal |last1=Campbell |first1=J. P. |last2=Zhang |first2=M. |last3=Hwang |first3=T. S. |last4=Bailey |first4=S. T. |last5=Wilson |first5=D. J. |last6=Jia |first6=Y. |last7=Huang |first7=D. |date=2017-02-10 |title=Detailed Vascular Anatomy of the Human Retina by Projection-Resolved Optical Coherence Tomography Angiography |journal=Scientific Reports |language=en |volume=7 |pages=42201 |doi=10.1038/srep42201 |pmc=5301488 |pmid=28186181|bibcode=2017NatSR...742201C }} optic nerve,{{Cite journal |last1=Tan |first1=Ou |last2=Chopra |first2=Vikas |last3=Lu |first3=Ake Tzu-Hui |last4=Schuman |first4=Joel S. |last5=Ishikawa |first5=Hiroshi |last6=Varma |first6=Rohit |last7=Huang |first7=David |date=2009-09-10 |title=Detection of Macular Ganglion Cell Loss in Glaucoma by Fourier-Domain Optical Coherence Tomography |journal=Ophthalmology |language=en |volume=116 |issue=12 |pages=2305–14.e1–2 |doi=10.1016/j.ophtha.2009.05.025 |pmc=2787911 |pmid=19744726}}{{Cite journal |last1=Jia |first1=Yali |last2=Wei |first2=Eric |last3=Wang |first3=Xiaogang |last4=Zhang |first4=Xinbo |last5=Morrison |first5=John C. |last6=Parikh |first6=Mansi |last7=Lombardi |first7=Lori H. |last8=Gattey |first8=Devin M. |last9=Armour |first9=Rebecca L. |last10=Edmunds |first10=Beth |last11=Kraus |first11=Martin F. |last12=Fujimoto |first12=James G. |last13=Huang |first13=David |date=2014-03-12 |title=Optical Coherence Tomography Angiography of Optic Disc Perfusion in Glaucoma |journal=Ophthalmology |language=en |volume=121 |issue=7 |pages=1322–1332 |doi=10.1016/j.ophtha.2014.01.021 |pmc=4082728 |pmid=24629312}} and anterior segment diseases in the eye,{{Cite journal |last1=Li |first1=Yan |last2=Tan |first2=Ou |last3=Brass |first3=Robert |last4=Weiss |first4=Jack L. |last5=Huang |first5=David |date=2012-08-20 |title=Corneal Epithelial Thickness Mapping by Fourier-domain Optical Coherence Tomography in Normal and Keratoconic Eyes |journal=Ophthalmology |language=en |volume=119 |issue=12 |pages=2425–2433 |doi=10.1016/j.ophtha.2012.06.023 |pmc=3514625 |pmid=22917888}} as well as ocular manifestations of neurological diseases.{{Cite journal |last1=Wang |first1=Xiaogang |last2=Jia |first2=Yali |last3=Spain |first3=Rebecca |last4=Potsaid |first4=Benjamin |last5=Liu |first5=Jonathan J |last6=Baumann |first6=Bernhard |last7=Hornegger |first7=Joachim |last8=Fujimoto |first8=James G |last9=Wu |first9=Qiang |last10=Huang |first10=David |date=October 2014 |title=Optical coherence tomography angiography of optic nerve head and parafovea in multiple sclerosis |journal=British Journal of Ophthalmology |language=en |volume=98 |issue=10 |pages=1368–1373 |doi=10.1136/bjophthalmol-2013-304547 |pmid=24831719 |pmc=4598177 |issn=0007-1161}}{{Cite journal |last1=Spain |first1=Rebecca I |last2=Liu |first2=Liang |last3=Zhang |first3=Xinbo |last4=Jia |first4=Yali |last5=Tan |first5=Ou |last6=Bourdette |first6=Dennis |last7=Huang |first7=David |date=April 2018 |title=Optical coherence tomography angiography enhances the detection of optic nerve damage in multiple sclerosis |journal=British Journal of Ophthalmology |language=en |volume=102 |issue=4 |pages=520–524 |doi=10.1136/bjophthalmol-2017-310477 |pmid=28814415 |pmc=6467481 |issn=0007-1161}} He has published over 350 articles{{Cite web |date= |title=David Huang's Bibliography |url=https://www.ncbi.nlm.nih.gov/sites/myncbi/david.huang.1/bibliography/40347588/public/?sort=date&direction=ascending |access-date=January 18, 2025 |website=National Library of Medicine}} in peer-reviewed scientific journals that have been cited over 66,000 times (H-index 100.{{Cite web |title=David Huang, MD, PhD |url=https://scholar.google.com/citations?user=SqEvY68AAAAJ |access-date=2025-01-19 |website=scholar.google.com}} He is a co-founder and president emeritus of the International Ocular Circulation Society{{Cite web |last=Society |first=International Ocular Circulation |title=International Ocular Circulation Society |url=https://ocularcirculation.org/ |access-date=2025-01-19 |website=International Ocular Circulation Society |language=en-US}}

• 2012 Champalimaud Vision Award{{Cite web |title=2012: Williams & Fujimoto, Huang, Puliafito, Schuman, Swanson {{!}} Champalimaud Foundation |url=https://www.fchampalimaud.org/awardees/2012-williams-fujimoto-huang-puliafito-schuman-swanson |access-date=2025-01-19 |website=www.fchampalimaud.org}}
• 2013 Jonas Friedenwald Award,{{Cite web |date=2012-06-11 |title=David Huang to win ARVO award for OCT work in ophthalmology |url=https://www.laserfocusworld.com/biooptics/bioimaging/optical-coherence-tomography/article/14193656/david-huang-to-win-arvo-award-for-oct-work-in-ophthalmology |access-date=2025-01-19 |website=Laser Focus World |language=en}} Association for Research in Vision & Ophthalmology
• 2017 Fritz J. and Dolores H. Russ prize{{Cite web |title=2017 Fritz J. and Dolores H. Russ Prize Recipients |url=https://www.nae.edu/19579/165897/20676/166043/20683/55292/164386/2017Russ |access-date=2025-01-19 |website=NAE Website |language=en}}
• 2023 Induction to National Academy of Engineering
• 2023 Lasker-DeBakey Clinical Medical Research Award{{Cite web |last=Admin |first=Lasker |title=OCT—for rapid detection of diseases of the retina |url=https://laskerfoundation.org/winners/optical-coherence-tomography/ |access-date=2025-01-19 |website=Lasker Foundation |language=en-US}}
• 2023 National Medal of Technology and Innovation{{Cite web |date=2023-10-24 |title=Four from MIT awarded National Medals of Technology, Science |url=https://news.mit.edu/2023/national-medals-technology-science-recipients-1024 |access-date=2025-01-19 |website=MIT News {{!}} Massachusetts Institute of Technology |language=en}}
• 2024 Induction to National Academy of Medicine
• 2024 Oregon History Maker, Oregon Historical Society{{Cite web |title=History Makers |url=https://www.ohs.org/support/history-makers.cfm |access-date=2025-01-19 |website=Oregon Historical Society}}
• 2025 Induction to the National Inventors Hall of Fame

{{reflist}}

{{DEFAULTSORT:Huang, David}}

Category:1964 births

Category:Living people

Category:American ophthalmologists

Category:American biomedical engineers

Category:21st-century American inventors

Category:Cleveland Clinic people

Category:American people of Taiwanese descent

Category:University of Southern California faculty

Category:Oregon Health & Science University faculty