Decaprenylphospho-beta-D-ribofuranose 2-oxidase

{{Infobox enzyme

| Name = Decaprenylphospho-beta-D-ribofuranose 2-oxidase

| EC_number = 1.1.98.3

| CAS_number =

| GO_code =

| image =

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Decaprenylphospho-beta-D-ribofuranose 2-oxidase ({{EC number|1.1.98.3}}, decaprenylphosphoryl-beta-D-ribofuranose 2'-epimerase, Rv3790, DprE1) is an enzyme with systematic name trans,octacis-decaprenylphospho-beta-D-ribofuranose:FAD 2-oxidoreductase.{{cite journal | vauthors = Ribeiro AL, Degiacomi G, Ewann F, Buroni S, Incandela ML, Chiarelli LR, Mori G, Kim J, Contreras-Dominguez M, Park YS, Han SJ, Brodin P, Valentini G, Rizzi M, Riccardi G, Pasca MR | title = Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis | journal = PLOS ONE | volume = 6 | issue = 11 | pages = e26675 | year = 2011 | pmid = 22069462 | pmc = 3206020 | doi = 10.1371/journal.pone.0026675 | bibcode = 2011PLoSO...626675D | doi-access = free }}{{cite journal | vauthors = Trefzer C, Škovierová H, Buroni S, Bobovská A, Nenci S, Molteni E, Pojer F, Pasca MR, Makarov V, Cole ST, Riccardi G, Mikušová K, Johnsson K | title = Benzothiazinones are suicide inhibitors of mycobacterial decaprenylphosphoryl-β-D-ribofuranose 2'-oxidase DprE1 | journal = Journal of the American Chemical Society | volume = 134 | issue = 2 | pages = 912–5 | date = January 2012 | pmid = 22188377 | doi = 10.1021/ja211042r | url = http://infoscience.epfl.ch/record/174323 }} This enzyme catalyses the following chemical reaction

: trans,octacis-decaprenylphospho-beta-D-ribofuranose + FAD $\backslash rightleftharpoons$ trans,octacis-decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose + FADH₂

This enzyme from the bacterium Mycobacterium smegmatis participates in epimerization of trans,octacis-decaprenylphospho-beta-D-ribofuranose to trans,octacis-decaprenylphospho-beta-D-arabinoofuranose.