Deconditioning

{{Short description|Adaptation of an organism to less demanding environment}}Deconditioning is adaptation of an organism to a less demanding environment, or, alternatively, the decrease of physiological adaptation to normal conditions. Deconditioning can result from decreased physical activity, prescribed bed rest, orthopedic casting, paralysis, aging.McGraw-Hill Encyclopedia of Science and Technology{{cite book |title=Lifestyle Modifications in Pharmacotherapy |last=Lenz |first=Thomas L. |year=2007 |publisher=Lippincott Williams & Wilkins |location=Baltimore |isbn=978-0-7817-7651-6 |page=298}} A particular interest in the study of deconditioning is in aerospace medicine, to diagnose, fight, and prevent adverse effects of the conditions of space flight.

Deconditioning due to decreased physical effort results in muscle loss, including heart muscles.

Deconditioning due to lack of gravity or non-standard gravity action (e.g., during bed rest) results in abnormal distribution of body fluids.{{cite book |title=Cardiac Nursing |last=Woods |first=Susan L. |author2=Erika Sivarajan Froelicher |author3=Sandra Adams Motzer |year=2004 |publisher=Lippincott Williams & Wilkins |location=Philadelphia |isbn=0-7817-4718-X |page=921 |url=https://books.google.com/books?id=_vWmbeuYRN8C&q=%22bed+rest+is%22&pg=RA1-PA921 |accessdate=2013-04-07}}