Demetrius Klee Lopes
{{Short description|American neurosurgeon}}
{{Infobox person
| honorific_prefix =
| name = Demetrius Klee Lopes
| image = Demetrius Lopes 2.jpg
| caption =
| birth_name =
| birth_date = {{birth date and age|1970|03|19}}
| birth_place = Chicago{{cite web
|url= https://www.chicagotribune.com/2006/05/21/you-will-see-dr-mcdreamy-now/
|title= You will see Dr. McDreamy now
|author = Beth Sammon
|date = 2006-05-21
|publisher = Chicago Tribune
|archive-url = https://web.archive.org/web/20170816020409/http://articles.chicagotribune.com/2006-05-21/features/0605210436_1_lopes-patrick-dempsey-boy
|archive-date = 2017-08-16
|url-status= live
|access-date=2017-11-08}}
| nationality = American
| education = Federal University of Rio Grande do Sul (1993), State University of New York at Buffalo (1995)
| occupation = Neurosurgeon
| years_active = 1994 – present
| known_for = Neuroendovascular surgery
| partner =
| awards =
| website = {{URL|http://www.demetriuslopesmd.com/}}
}}
Demetrius Klee Lopes (born March 19, 1970) is a cerebrovascular neurosurgeon specializing in neuroendovascular therapy. At Advocate Health, he serves as medical director of the cerebrovascular and neuroendovascular program and is co-director of their stroke program.{{cite web|url=https://www.beckersspine.com/spine/item/41998-spine-surgeon-joins-advocate-brain-spine-institute-as-director-of-cerebrovascular-program-5-takeaways.html|title=Neurosurgeon joins Advocate Brain & Spine Institute as director of cerebrovascular program: 5 takeaways|author=Mackenzie Garrity|date=2018-07-31|publisher=The Becker's Spine Review|archive-url=https://web.archive.org/web/20180801184259/https://www.beckersspine.com/spine/item/41998-spine-surgeon-joins-advocate-brain-spine-institute-as-director-of-cerebrovascular-program-5-takeaways.html|archive-date=2018-08-01|access-date=2018-08-01}}
Lopes is a guest faculty member of Brigham and Women's Hospital Cerebrovascular and Skull Base Symposium at Harvard Medical School.{{cite web
|url= http://cmeregistration.hms.harvard.edu/events/brigham-and-women-s-hospital-cerebrovascular-and-skull-base-symposium/speakers-b630baed0d3345aa813fdd7723f59e43.aspx
|title= Brigham and Women's Hospital Cerebrovascular and Skull Base Symposium: Faculty
|publisher= Harvard Medical School
|archive-url = https://web.archive.org/web/20170926112440/http://cmeregistration.hms.harvard.edu/events/brigham-and-women-s-hospital-cerebrovascular-and-skull-base-symposium/speakers-b630baed0d3345aa813fdd7723f59e43.aspx
|archive-date = 2017-09-26
|access-date=2017-11-08}} Lopes is the founder of nonprofit Cure4Stroke Foundation,{{cite web|url=http://www.cure4stroke.org/about/mission-board-of-directors/|title=Mission and Board of Directors |website=www.cure4stroke.org|archive-url= https://web.archive.org/web/20170906054046/http://www.cure4stroke.org/about/mission-board-of-directors/|archive-date=2017-09-06|access-date=2017-11-08}} editor in chief of "Neurovascular Exchange" educational website{{cite web
|url= https://www.rushu.rush.edu/faculty/demetrius-k-lopes-md
|title= Demetrius K. Lopes, MD
|publisher= Rush University
|archive-url = https://web.archive.org/web/20170319132055/http://www.nwitimes.com/business/jobs-and-employment/workplace/progress/region-hospitals-work-to-stop-health-care-migration/article_314b9f97-1116-5a53-bd46-6f7fe4f64608.html
|archive-date = 2017-03-19
|access-date=2017-11-08}} and serves on the organizing committee of the annual World Live Neurovascular Conference.{{cite web|url=http://www.wlnc.org/en/COMMITTEES.html|title=COMMITTEES|first=Milk Creative & Events (by DEKON|last=Group)|website=www.wlnc.org|access-date=20 August 2017}}
Lopes' contributions to neurovascular surgery have improved safety and decreased the disabilities caused by stroke, brain aneurysms and arterial malformations. He collaborated on major studies that defined the current indications for mechanical thrombectomy for the treatment of acute stroke. In addition, Lopes had contributed significantly to the development of flow diversion treatment for cerebral aneurysms.
Early life and education
Born on March 19, 1970, Lopes lived in Brazil until 1993. He began his medical education in 1987 at Federal University of Rio Grande do Sul. After completing his doctorate in medicine in 1993, he completed his residency and fellowship at State University of New York at Buffalo.
Career
In 2001, Lopes joined Rush University Medical Center. In May 2006, he was voted Chicago's "Dr. McDreamy" by the readers of the Chicago Tribune.
In 2013, Lopes founded the nonprofit Cure4Stroke Foundation,{{cite web
|url= https://www.donatecube.com/cure4stroke.org
|title= cure4stroke.org
|publisher= donatecube.com
|archive-url = https://web.archive.org/web/20171108081802/https://www.donatecube.com/cure4stroke.org
|archive-date=2017-11-08
|access-date=2017-11-08}} which aims to raise stroke awareness and celebrate stroke survivors.{{cite web
|url= https://www.active.com/chicago-il/running/distance-running-races/cure4stroke-foundation-presents-move-that-body-main-event-5k-fun-run-walk-zumba-and-yin-yoga-2015
|title= Cure4Stroke Foundation Presents "MOVE that BODY!" Main Event: 5k Fun Run/Walk, Zumba, and Yin Yoga
|publisher= active.com
|date=2015-07-07
|archive-url = https://web.archive.org/web/20171108081802/https://www.donatecube.com/cure4stroke.org
|archive-date=2017-11-08
|access-date=2017-11-08}}
In 2015, Lopes published articles confirming that the use of endovascular therapy for ischemic stroke improves patient outcomes.{{cite journal|last1=Saver|first1= Jeffrey L.|last2= Goyal|first2= Mayank |last3= Bonafe|first3= Alain|last4= Diener|first4= Hans-Christoph|last5= Levy |first5= Elad I.|last6= Pereira|first6= Vitor M.|last7= Albers|first7= Gregory W.|last8= Cognard|first8= Christophe|last9= Cohen|first9= David J.|last10= Hacke|first10= Werner|last11= Jansen|first11= Olav|last12= Jovin |first12= Tudor G.|last13= Mattle|first13= Heinrich P.|last14= Nogueira |first14= Raul G.|last15= Siddiqui|first15= Adnan H.|last16= Yavagal |first16= Dileep R.|last17= Baxter|first17= Blaise W.|last18= Devlin |first18= Thomas G.|last19= Lopes |first19= Demetrius K.|last20= Reddy |first20= Vivek K.|display-authors=etal|date=June 2015|title=Stent-Retriever Thrombectomy after Intravenous t-PA vs. t-PA Alone in Stroke|journal=New England Journal of Medicine|volume=372|issue=24|pages=2285–2295|doi=10.1056/NEJMoa1415061|pmid=25882376|s2cid= 6570411|url= https://boris.unibe.ch/69540/1/Saver-2015-Stent-Retriever%20Thrombectomy%20after.pdf}}{{cite web
|url= http://www.medicaldaily.com/new-approach-stroke-treatment-offers-hope-severe-stroke-patients-329808
|title= New Approach To Stroke Treatment Offers Hope To Severe Stroke Patients
|date = 2015-04-17
|author = Lecia Bushak
|publisher= Medical Daily
|archive-url = https://web.archive.org/web/20151028173453/http://www.medicaldaily.com/new-approach-stroke-treatment-offers-hope-severe-stroke-patients-329808
|archive-date = 2015-10-28
|access-date=2017-11-08}}{{cite web
|url= https://www.sciencedaily.com/releases/2015/04/150417085418.htm
|title= Effectiveness of new stroke treatment confirmed
|date = 2015-04-17
|publisher= Science Daily
|archive-url = https://web.archive.org/web/20150420052050/https://www.sciencedaily.com/releases/2015/04/150417085418.htm
|archive-date = 2015-04-20
|access-date=2017-11-08}}
In 2015, along with Elad Levy, Lopes performed research resulting in paradigm shifts in the treatment of cerebrovascular diseases, including being the US Interventional Principal Investigator for the SWIFT PRIME trials.{{cite journal |vauthors=Saver JL, Goyal M, Bonafe A, Diener HC, Levy EI, Pereira VM, Albers GW, Cognard C, Cohen DJ, Hacke W, Jansen O, Jovin TG, Mattle HP, Nogueira RG, Siddiqui AH, Yavagal DR, Baxter BW, Devlin TG, Lopes DK, Reddy VK, du Mesnil de Rochemont R, Singer OC, Jahan R |title=Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke |journal=N. Engl. J. Med. |volume=372 |issue=24 |pages=2285–95 |date=June 2015 |pmid=25882376 |doi=10.1056/NEJMoa1415061 |s2cid=6570411 |url=https://boris.unibe.ch/69540/1/Saver-2015-Stent-Retriever%20Thrombectomy%20after.pdf }} Lopes also conducted research on the efficacy and safety of endovascular thrombectomy in 2018.{{cite journal |vauthors=Nogueira RG, Jadhav AP, Haussen DC, Bonafe A, Budzik RF, Bhuva P, Yavagal DR, Ribo M, Cognard C, Hanel RA, Sila CA, Hassan AE, Millan M, Levy EI, Mitchell P, Chen M, English JD, Shah QA, Silver FL, Pereira VM, Mehta BP, Baxter BW, Abraham MG, Cardona P, Veznedaroglu E, Hellinger FR, Feng L, Kirmani JF, Lopes DK, Jankowitz BT, Frankel MR, Costalat V, Vora NA, Yoo AJ, Malik AM, Furlan AJ, Rubiera M, Aghaebrahim A, Olivot JM, Tekle WG, Shields R, Graves T, Lewis RJ, Smith WS, Liebeskind DS, Saver JL, Jovin TG |title=Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct |journal=N. Engl. J. Med. |volume=378 |issue=1 |pages=11–21 |date=January 2018 |pmid=29129157 |doi=10.1056/NEJMoa1706442|doi-access=free }}
In July 2018, Lopes joined Advocate Health Care as co-director of the stroke program.
In 2019, Lopes published a preliminary study on usage of the pipeline embolization device to treat small to medium-sized intracranial aneurysms,{{cite journal |vauthors=Hanel RA, Kallmes DF, Lopes DK, Nelson PK, Siddiqui A, Jabbour P, Pereira VM, Szikora István I, Zaidat OO, Bettegowda C, Colby GP, Mokin M, Schirmer C, Hellinger FR, Given Ii C, Krings T, Taussky P, Toth G, Fraser JF, Chen M, Priest R, Kan P, Fiorella D, Frei D, Aagaard-Kienitz B, Diaz O, Malek AM, Cawley CM, Puri AS |title=Prospective study on embolization of intracranial aneurysms with the pipeline device: the PREMIER study 1 year results |journal=J Neurointerv Surg |volume= 12|issue= 1|pages= 62–66|date=July 2019 |pmid=31308197 |doi=10.1136/neurintsurg-2019-015091 |pmc=6996098}}{{cite journal |vauthors=Jankowitz BT, Jadhav AP, Gross B, Jovin TG, Alhajeri AA, Fraser JF, Hanel RA, Sauvageau E, Aghaebrahim A, Frei D, Bellon R, Loy D, Puri AS, Malek AM, Thomas A, Toth G, Lopes DK, Crowley RW, Arthur AS, Reavey-Cantwell J, Lin E, Siddiqui AH, Alexander MJ, Khaldi A, Colby GP, Caplan JM, Satti SR, Turk AS, Spiotta AM, Klucznik R, Hallam DK, Kung D, Froehler MT, Callison RC, Kan P, Hetts SW, Zaidat OO |title=Pivotal trial of the Neuroform Atlas stent for treatment of posterior circulation aneurysms: one-year outcomes |journal=J Neurointerv Surg |volume= 14|issue= 2|pages= 143–148|date=March 2021 |pmid=33722961 |doi=10.1136/neurintsurg-2020-017115 |pmc=8785011 |url=https://jnis.bmj.com/content/neurintsurg/early/2021/03/14/neurintsurg-2020-017115.full.pdf|doi-access=free }} and has also demonstrated its safety and efficacy for patients under 22 years old.{{cite journal |vauthors=Cherian J, Srinivasan V, Froehler MT, Grossberg JA, Cawley CM, Hanel RA, Puri A, Dumont T, Ducruet AF, Albuquerque F, Arthur A, Cheema A, Spiotta A, Anadani M, Lopes D, Saied A, Kim L, Kelly CM, Chen PR, Mocco J, De Leacy R, Powers CJ, Grandhi R, Fargen KM, Chen SR, Johnson JN, Lam S, Kan P |title=Flow Diversion for Treatment of Intracranial Aneurysms in Pediatric Patients: Multicenter Case Series |journal=Neurosurgery |volume= 87|pages= 53–62|date=September 2019 |pmid=31557290 |doi=10.1093/neuros/nyz380 |url=https://academic.oup.com/neurosurgery/advance-article-abstract/doi/10.1093/neuros/nyz380/5574634?redirectedFrom=fulltext|url-access=subscription }} Later that year, Lopes also published research results demonstrating the safety and efficacy of transvenous embolization for treating arteriovenous malformations.{{cite journal | last1 = Brahimaj | first1 = BC | last2 = Keigher | first2 = K | last3 = Lopes | first3 = DK | year = 2019 | title = Transvenous arteriovenous malformation embolization | url = https://jnis.bmj.com/content/early/2019/12/19/neurintsurg-2019-015515 | journal = Journal of NeuroInterventional Surgery | volume = 12| issue = 3| pages = 332| doi = 10.1136/neurintsurg-2019-015515 | pmid = 31862831 | s2cid = 209434543 | url-access = subscription }} Lopes published another similar study in July 2020.{{cite journal |vauthors=Ughi GJ, Marosfoi MG, King RM, Caroff J, Peterson LM, Duncan BH, Langan ET, Collins A, Leporati A, Rousselle S, Lopes DK, Gounis MJ, Puri AS |title=A neurovascular high-frequency optical coherence tomography system enables in situ cerebrovascular volumetric microscopy |journal=Nature Communications |volume=11 |issue=1 |pages=3851 |date=July 2020 |pmid=32737314 |pmc=7395105 |doi=10.1038/s41467-020-17702-7 |bibcode=2020NatCo..11.3851U |url=}}
Selected publications
- {{cite journal | pmid = 25882376 | doi=10.1056/NEJMoa1415061 | volume=372 | title=Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke | year=2015 | journal=N Engl J Med | pages=2285–95 | last1 = Saver | first1 = JL | last2 = Goyal | first2 = M | last3 = Bonafe | first3 = A | last4 = Diener | first4 = HC | last5 = Levy | first5 = EI | last6 = Pereira | first6 = VM | last7 = Albers | first7 = GW | last8 = Cognard | first8 = C | last9 = Cohen | first9 = DJ | last10 = Hacke | first10 = W | last11 = Jansen | first11 = O | last12 = Jovin | first12 = TG | last13 = Mattle | first13 = HP | last14 = Nogueira | first14 = RG | last15 = Siddiqui | first15 = AH | last16 = Yavagal | first16 = DR | last17 = Baxter | first17 = BW | last18 = Devlin | first18 = TG | last19 = Lopes | first19 = DK | last20 = Reddy | first20 = VK | last21 = de Rochemont | first21 = R | last22 = Singer | first22 = OC | last23 = Jahan | first23 = R| issue=24 | s2cid=6570411 | url=https://boris.unibe.ch/69540/1/Saver-2015-Stent-Retriever%20Thrombectomy%20after.pdf }}
- {{cite journal | pmid = 28828131 | doi=10.1016/j.radcr.2017.03.012 | volume=12 | title=Giant vein of Galen malformation in an adult | pmc=5551915 | year=2017 | journal=Radiol Case Rep | pages=585–589 | last1 = Kerolus | first1 = MG | last2 = Tan | first2 = LA | last3 = Lopes | first3 = DK| issue=3 }}
- {{cite journal | pmid = 28449126 | doi=10.1093/neuros/nyx085 | volume=81 | title=Results of the ANSWER Trial Using the PulseRider for the Treatment of Broad-Necked, Bifurcation Aneurysms | year=2017 | journal=Neurosurgery | pages=56–65 | last1 = Spiotta | first1 = AM | last2 = Derdeyn | first2 = CP | last3 = Tateshima | first3 = S | last4 = Mocco | first4 = J | last5 = Crowley | first5 = RW | last6 = Liu | first6 = KC | last7 = Jensen | first7 = L | last8 = Ebersole | first8 = K | last9 = Reeves | first9 = A | last10 = Lopes | first10 = DK | last11 = Hanel | first11 = RA | last12 = Sauvageau | first12 = E | last13 = Duckwiler | first13 = G | last14 = Siddiqui | first14 = A | last15 = Levy | first15 = E | last16 = Puri | first16 = A | last17 = Pride | first17 = L | last18 = Novakovic | first18 = R | last19 = Chaudry | first19 = MI | last20 = Turner | first20 = RD | last21 = Turk | first21 = AS| s2cid=3806248 }}
- {{cite journal | pmid = 28596447 | doi=10.1161/STROKEAHA.116.016253 | volume=48 | title=Impact of Thrombus Length on Outcomes After Intra-Arterial Aspiration Thrombectomy in the THERAPY Trial | year=2017 | journal=Stroke | pages=1895–1900 | last1 = Yoo | first1 = AJ | last2 = Khatri | first2 = P | last3 = Mocco | first3 = J | last4 = Zaidat | first4 = OO | last5 = Gupta | first5 = R | last6 = Frei | first6 = D | last7 = Lopes | first7 = D | last8 = Shownkeen | first8 = H | last9 = Berkhemer | first9 = OA | last10 = Meyer | first10 = D | last11 = Hak | first11 = SS | last12 = Kuo | first12 = SS | last13 = Buell | first13 = H | last14 = Bose | first14 = A | last15 = Sit | first15 = SP | last16 = von Kummer | first16 = R| issue=7 | s2cid=279737 | doi-access = free }}
- {{cite journal | pmid = 29129157 | doi=10.1056/NEJMoa1706442 | volume=378 | title=Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct | year=2018 | journal=N Engl J Med | pages=11–21 | last1 = Nogueira | first1 = RG | last2 = Jadhav | first2 = AP | last3 = Haussen | first3 = DC | last4 = Bonafe | first4 = A | last5 = Budzik | first5 = RF | last6 = Bhuva | first6 = P | last7 = Yavagal | first7 = DR | last8 = Ribo | first8 = M | last9 = Cognard | first9 = C | last10 = Hanel | first10 = RA | last11 = Sila | first11 = CA | last12 = Hassan | first12 = AE | last13 = Millan | first13 = M | last14 = Levy | first14 = EI | last15 = Mitchell | first15 = P | last16 = Chen | first16 = M | last17 = English | first17 = JD | last18 = Shah | first18 = QA | last19 = Silver | first19 = FL | last20 = Pereira | first20 = VM | last21 = Mehta | first21 = BP | last22 = Baxter | first22 = BW | last23 = Abraham | first23 = MG | last24 = Cardona | first24 = P | last25 = Veznedaroglu | first25 = E | last26 = Hellinger | first26 = FR | last27 = Feng | first27 = L | last28 = Kirmani | first28 = JF | last29 = Lopes | first29 = DK | last30 = Jankowitz | first30 = BT | last31 = Frankel | first31 = MR | last32 = Costalat | first32 = V | last33 = Vora | first33 = NA | last34 = Yoo | first34 = AJ | last35 = Malik | first35 = AM | last36 = Furlan | first36 = AJ | last37 = Rubiera | first37 = M | last38 = Aghaebrahim | first38 = A | last39 = Olivot | first39 = JM | last40 = Tekle | first40 = WG | last41 = Shields | first41 = R | last42 = Graves | first42 = T | last43 = Lewis | first43 = RJ | last44 = Smith | first44 = WS | last45 = Liebeskind | first45 = DS | last46 = Saver | first46 = JL | last47 = Jovin | first47 = TG| issue=1 | doi-access = free }}
References
{{Reflist}}
External links
- [http://wlnc.org/en/DEMETRIUS-LOPES.html Demetrius Lopes profile at the World Live Neurovascular Conference]
- [http://www.cure4stroke.org/ Cure4Stroke Foundation]
- [https://www.neurovascularexchange.com Neurovascular Exchange]
- [https://doctors.advocatehealth.com/a-demetrius-k-lopes-park-ridge-neurosurgery-3 Advocate Aurora Health - Dr. Demetrius Lopes]
{{authority control}}
{{DEFAULTSORT:Lopes, Demetrius}}
Category:American neurosurgeons
Category:American neuroscientists
Category:American medical academics
Category:American medical researchers
Category:Rush University faculty
Category:Federal University of Rio Grande do Sul alumni
Category:University at Buffalo alumni