Dibutylchloromethyltin chloride
{{Chembox
| Name = Dibutylchloromethyltin chloride
| ImageFile = Dibutylchloromethyltin chloride.svg
| IUPACName = Dibutyl(chloro)(chloromethyl)stannane
| OtherNames = DBCT
| Section1 = {{Chembox Identifiers
| CASNo = 61553-17-1
| CASNo_Ref = {{cascite|correct|CAS}}
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = N2J5VG8RQD
| ChemSpiderID = 164378
| PubChem = 189186
| SMILES = CCCC[Sn](CCCC)(CCl)Cl
| StdInChI = InChI=1S/2C4H9.CH2Cl.ClH.Sn/c2*1-3-4-2;1-2;;/h2*1,3-4H2,2H3;1H2;1H;/q;;;;+1/p-1
| StdInChIKey = XWFCEWFXSQFZPI-UHFFFAOYSA-M
}}
| Section2 = {{Chembox Properties
| C=9|H=20|Cl=2|Sn=1
}}
| Section3 = {{Chembox Hazards
| MainHazards = Toxic, vesicant
}}
}}
Dibutylchloromethyltin chloride (DBCT) is a toxic organotin compound. It is a potent and irreversible ATP synthase inhibitor.{{cite journal |last1=Cain |first1=K |last2=Partis |first2=MD |last3=Griffiths |first3=DE |title=Dibutylchloromethyltin chloride, a covalent inhibitor of the adenosine triphosphate synthase complex. |journal=The Biochemical Journal |date=15 September 1977 |volume=166 |issue=3 |pages=593–602 |pmid=145860 |pmc=1165045|doi=10.1042/bj1660593 }}{{cite journal |last1=Moore |first1=Anthony L. |last2=Linnett |first2=Paul E. |last3=Beechey |first3=R. Brian |title=Dibutylchloromethyltin chloride, a potent inhibitor of electron transport in plant mitochondria |journal=Journal of Bioenergetics and Biomembranes |date=August 1980 |volume=12 |issue=3–4 |pages=309–323 |doi=10.1007/bf00744691|pmid=7217044 |s2cid=29130410 }}{{cite journal |last1=Diwan |first1=Joyce Johnson |title=Some effects of dibutylchloromethyltin chloride and other reagents on mitochondrial K+ flux |journal=Journal of Bioenergetics and Biomembranes |date=February 1982 |volume=14 |issue=1 |pages=15–22 |doi=10.1007/bf00744076|pmid=7142136 |s2cid=24153839 }} DBCT is a volatile liquid with powerful vesicant effects.
See also
References
{{reflist}}
Category:ATP synthase inhibitors
Category:Chloromethyl compounds
{{Organic-compound-stub}}