Discodermia

{{Short description|Genus of sponges}}

{{Automatic taxobox

| image = Discodermia ramifera (10.7717-peerj.8703) Figure 2 (cropped).png

| image_caption = Discodermia ramifera

| taxon = Discodermia

| authority = du Bocage, 1869{{cite WoRMS |title=Discodermia |id=132089 |access-date=12 Sep 2020}}

| synonyms =

  • Collinella Schmidt, 1879
  • Desmahabana Alcolado & Gotera, 1986

}}

Discodermia is a genus of deep-water sea sponge.{{cite journal|vauthors=Brück WM, Sennett SH, Pomponi SA, Willenz P, McCarthy PJ|year=2008|title=Identification of the bacterial symbiont Entotheonella sp. in the mesohyl of the marine sponge Discodermia sp.|url=http://fau.digital.flvc.org/islandora/object/fau%3A5984|journal=The ISME Journal|volume=2|issue=3|pages=335–339|doi=10.1038/ismej.2007.91|pmid=18256706|doi-access=free|bibcode=2008ISMEJ...2..335B }}

Species

The following species are accepted within Discodermia:

{{div col begin|colwidth=30em}}

{{div col end}}

Pharmacology

image:Discodermin B-D.png

D. dissoluta is of interest to bio and organic chemists because it produces (+)-discodermolide, a polyketide natural product with immunosuppressive and cancer killing properties.{{cite journal|vauthors=Singh R, Sharma M, Joshi P, Rawat DS|year=2008|title=Clinical status of anti-cancer agents derived from marine sources|journal=Anti-Cancer Agents in Medicinal Chemistry|volume=8|issue=6|pages=603–617|doi=10.2174/187152008785133074|pmid=18690825}}

Antimicrobial/anticancer peptides called discodermins have been isolated from D. kiiensis.{{cite journal|pmid=20065108|year=2010|last1=Otero-González|first1=AJ|last2=Magalhaes|first2=BS|last3=Garcia-Villarino|first3=M|last4=Lopez-Abarrategui| first4=C |last5=Sousa |first5=DA |last6=Dias |first6=SC |last7=Franco |first7=OL |title=Antimicrobial peptides from marine invertebrates as a new frontier for microbial infection control|volume=24|issue=5|pages=1320–34|doi=10.1096/fj.09-143388|journal=FASEB Journal|doi-access=free |s2cid=23976702}}

References

{{Reflist}}

{{Taxonbar|from=Q4115838}}

Category:Tetractinellida

Category:Sponges described in 1869

Category:Sponge genera

{{Demosponge-stub}}