Diverted total synthesis

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Design and synthesis of analogues of natural products Martin E. Maiera Org. Biomol. Chem., 2015,13, 5302-5343 {{doi|10.1039/C5OB00169B}}

Small Molecule Natural Products in the Discovery of Therapeutic Agents:  The Synthesis Connection Rebecca M. Wilson‡ and Samuel J. Danishefsky*,‡,§ The Journal of Organic Chemistry 2006 71 (22), 8329-8351 {{doi|10.1021/jo0610053}}

Fürstner, A. (2011), From Total Synthesis to Diverted Total Synthesis: Case Studies in the Amphidinolide Series. Isr. J. Chem., 51: 329–345. {{doi|10.1002/ijch.201100006}}

Diverted total synthesis: Preparation of a focused library of latrunculin analogues and evaluation of their actin-binding properties Alois Fürstner, Douglas Kirk, Michaël D. B. Fenster, Christophe Aïssa, Dominic De Souza, and Oliver Müller PNAS vol. 102 no. 23 8103–8108 2005, {{doi|10.1073/pnas.0501441102}}

Lei, X. and Danishefsky, Samuel J. (2008), Efficient Synthesis of a Novel Resorcyclide as Anticancer Agent Based on Hsp90 Inhibition. Adv. Synth. Catal., 350: 1677–1681. {{doi|10.1002/adsc.200800187}}

Diverted Total Synthesis Leads to the Generation of Promising Cell-Migration Inhibitors for Treatment of Tumor Metastasis: In vivo and Mechanistic Studies on the Migrastatin Core Ether Analog Thordur Oskarsson, Pavel Nagorny, Isaac J. Krauss, Lucy Perez, Mihirbaran Mandal, Guangli Yang, Ouathek Ouerfelli, Danhua Xiao, Malcolm A. S. Moore, Joan Massagué, and Samuel J. Danishefsky

Journal of the American Chemical Society 2010 132 (9), 3224-3228 {{doi|10.1021/ja9101503}}

Synthetic studies toward (+)-cortistatin A Zhang Wang, Mingji Dai, Peter K. Park Samuel J. Danishefsky Tetrahedron Volume 67, Issue 52, 30 December 2011, Pages 10249–10260 {{doi|10.1016/j.tet.2011.10.026}}

Design, synthesis, and evaluation of potent bryostatin analogs that modulate PKC translocation selectivity Paul A. Wender, Jeremy L. Baryza, Stacey E. Brenner, Brian A. DeChristopher, Brian A. Loy, Adam J. Schrier, and Vishal A. Verma Proc Natl Acad Sci U S A. 2011 Apr 26; 108(17): 6721–6726. {{doi|10.1073/pnas.1015270108}}

Emergence of potent inhibitors of metastasis in lung cancer via syntheses based on migrastatin Nicolas Lecomte, Jon T. Njardarson, Pavel Nagorny, Guangli Yang, Robert Downey, Ouathek Ouerfelli, Malcolm A. S. Moore, and Samuel J. Danishefsky Proc Natl Acad Sci U S A. 2011 Sep 13; 108(37): 15074-15078 {{doi|10.1073/pnas.1015247108}}

Nickel-catalyzed regiodivergent approach to macrolide motifs Abdur-Rafay Shareef, David H. Sherman and John Montgomery Chem. Sci., 2012,3, 892-895 {{doi|10.1039/C2SC00866A}}

Nitroso Diels-Alder (NDA) Reaction as an Efficient Tool for the Functionalization of Diene-Containing Natural Products Serena Carosso and Marvin J. Miller Org Biomol Chem. 2014 Oct 14; 12(38): 7445–7468 {{doi|10.1039/c4ob01033g}}

Counting on natural products for drug design Tiago Rodrigues, Daniel Reker, Petra Schneider & Gisbert Schneider Nature Chemistry 8, 531–541 (2016) {{doi|10.1038/nchem.2479}}

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Category:Total synthesis