Docking@Home

{{Short description|BOINC based volunteer computing project researching protein structure}}

{{Infobox distributed computing project

|screenshot=Docking@Home.gif

|operating system=Linux, macOS, and Windows

|platform=BOINC

|developer=University of Delaware

|website={{url|1=http://docking.cis.udel.edu/}}

|screenshot_size=250px}}

Docking@Home was a volunteer computing project hosted by the University of Delaware and running on the Berkeley Open Infrastructure for Network Computing (BOINC) software platform. It models protein-ligand docking using the CHARMM program. Volunteer computing allows an extensive search of protein-ligand docking conformations and selection of near-native ligand conformations are achieved by using ligand based hierarchical clustering.{{Cite book |last1=Estrada |first1=Trlce |last2=Armen |first2=Roger |last3=Taufer |first3=Michela |title=Proceedings of the First ACM International Conference on Bioinformatics and Computational Biology |chapter=Automatic selection of near-native protein-ligand conformations using a hierarchical clustering and volunteer computing |date=2010-08-02 |chapter-url=https://doi.org/10.1145/1854776.1854807 |series=BCB '10 |location=New York, NY, USA |publisher=Association for Computing Machinery |pages=204–213 |doi=10.1145/1854776.1854807 |isbn=978-1-4503-0438-2|s2cid=6040735 }} The ultimate aim was the development of new pharmaceutical drugs.

The project was retired on May 23, 2014.{{cite web|url=http://docking.cis.udel.edu/about/project/news.php#285|title=Docking@Home is Retiring|access-date=2014-06-15|archive-url=https://web.archive.org/web/20141017051439/http://docking.cis.udel.edu/about/project/news.php#285|archive-date=2014-10-17|url-status=dead}}