Dolichylphosphate-mannose phosphodiesterase

{{infobox enzyme

| Name = dolichylphosphate-mannose phosphodiesterase

| EC_number = 3.1.4.49

| CAS_number = 111839-07-7

| GO_code = 0047398

| image =

| width =

| caption =

}}

The enzyme dolichylphosphate-mannose phosphodiesterase (EC 3.1.4.49){{cite journal |vauthors=Tomita Y, Motokawa Y | date = 1987 | title = Characterization and partial purification of a novel mannosylphosphodolichol phosphodiesterase from chicken liver microsomes | journal = Eur. J. Biochem. | volume = 170 | pages = 363–8 | pmid = 2826159 | doi = 10.1111/j.1432-1033.1987.tb13708.x | issue = 1–2 | doi-access = free }} catalyzes the reaction

:dolichyl β-D-mannosyl phosphate + H₂O $\backslash rightleftharpoons$ dolichyl phosphate + D-mannose

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. The systematic name is dolichyl-β-D-mannosyl-phosphate dolichylphosphohydrolase. This enzyme is also called mannosylphosphodolichol phosphodiesterase.