Douglas R. Lowy
{{Infobox scientist
| name = Douglas R. Lowy
| image = Dr. Douglas.R.Lowy.jpg
| caption = Douglas R. Lowy, MD, Principal Deputy Director, National Cancer Institute
| field = Cancer biology
| alma_mater = {{Plainlist|
| awards = Lasker-DeBakey Clinical Medical Research Award (2017)
Sabin Gold Medal (2011)
}}
Douglas R. Lowy (born {{abbr|c.|circa}} 1940s) is the current Principal Deputy Director of the U.S. National Cancer Institute (NCI) and Chief of the Laboratory of Cellular Oncology within the Center for Cancer Research at NCI. Lowy served as Acting Director of NCI between April 2015 and October 2017 following the resignation of Harold E. Varmus, M.D., {{cite web|title=Douglas Lowy named Acting Director of the National Cancer Institute|url=http://www.cancer.gov/newscenter/newsfromnci/2015/lowy-named-acting-nci-director-april-2015|website=Website of the National Cancer Institute|date=April 2015 |access-date=1 April 2015}} {{PD-notice}}{{cite news |url=https://www.nytimes.com/2015/03/05/us/chief-of-national-cancer-institute-resigns.html?_r=0 |title=Chief of National Cancer Institute Resigns |first=Sabrina |last=Tavernise |date=March 4, 2015 |work= The New York Times |access-date=16 July 2015}} and again between April and November 2019, while Director Norman Sharpless served as the Acting Commissioner of the U.S. Food and Drug Administration.{{Cite news|url=https://www.nytimes.com/2019/03/12/health/fda-ned-sharpless.html|title=National Cancer Chief, Ned Sharpless, Named F.D.A.'s Acting Commissioner|last=Kaplan|first=Sheila|date=2019-03-12|work=The New York Times|access-date=2019-03-17|language=en-US|issn=0362-4331}} He resumed the role of Acting Director on May 1, 2022, when Sharpless stepped down until October 3, 2022 when Monica Bertagnolli was appointed Director.{{cite web | url=https://www.cancer.gov/news-events/press-releases/2022/bertagnolli-nci-director#:~:text=Monica%20M.,Institutes%20of%20Health%20(NIH). | title=Monica Bertagnolli becomes NCI director - NCI | date=3 October 2022 }}{{Cite web |date=2019-11-01 |title=NCI Acting Director Dr. Douglas R. Lowy - National Cancer Institute |url=https://www.cancer.gov/about-nci/leadership/director |access-date=2022-05-02 |website=www.cancer.gov |language=en}} He resumed the role again in November 2023 after Bertagnolli resigned to serve as director of the National Institutes of Health.{{cite web | url=https://www.nih.gov/news-events/news-releases/monica-bertagnolli-md-takes-helm-nih | title=Monica Bertagnolli, M.D., takes the helm at NIH | date=9 November 2023 }}
Lowy has served as Deputy Director of the NCI since 2010, alongside former directors Varmus and Sharpless and current director Bertagnolli.{{Cite web |date=2019-11-01 |title=NCI Principal Deputy Director Dr. Douglas R. Lowy - National Cancer Institute |url=https://www.cancer.gov/about-nci/leadership/nci-deputy-director |access-date=2022-03-24 |website=www.cancer.gov |language=en}} Lowy was co-recipient (along with Dr. John T. Schiller) of the National Medal of Technology and Innovation in 2014{{cite web|title=President Obama Presents the National Medals of Science & National Medals of Technology and Innovation|url=https://obamawhitehouse.archives.gov/the-press-office/2014/11/20/president-obama-presents-national-medals-science-national-medals-technol|via=National Archives|work=whitehouse.gov|date=20 November 2014 |access-date=2 April 2015}} and the Lasker-DeBakey Clinical Medical Research Award in 2017.
Biography
Lowy received his medical degree from the New York University School of Medicine, and trained in internal medicine at Stanford University and dermatology at Yale. He has directed a research laboratory at NCI since 1975, after receiving training as a Research Associate in the National Institute of Allergy and Infectious Diseases. Lowy is a member of the National Academy of Sciences (NAS) and of its Institute of Medicine. For his joint research with John T. Schiller on technology that enabled the development of preventive human papillomavirus (HPV) vaccines, he and Schiller received the 2007 Samuel J. Heyman Service to America Medal,{{cite web|title=2007 Federal Employees of the Year|url=http://servicetoamericamedals.org/SAM/recipients/profiles/fym07_lowy_schiller.shtml |archive-url=https://web.archive.org/web/20150108143245/http://servicetoamericamedals.org/SAM/recipients/profiles/fym07_lowy_schiller.shtml|archive-date=January 8, 2015|website=Service to America Medals|access-date=2015-04-02}} the 2011 Albert B. Sabin Gold Medal,{{cite web|title=Sabin Gold Medal Award|url=http://www.sabin.org/sabin-gold-medal-award|access-date=2 April 2015}} the 2012 National Medal of Technology and Innovation (awarded in 2014), and the Lasker-DeBakey Clinical Medical Research Award in 2017. He has also received the National Medal of Honor for Basic Research from the American Cancer Society.{{cite web|title=American Cancer Society to Present Highest Honor for Outstanding Contributions to Cancer Fight|url=http://pressroom.cancer.org/index.php?s=43&item=71|website=American Cancer Society|access-date=2 April 2015|archive-url=https://web.archive.org/web/20150914170856/http://pressroom.cancer.org/index.php?s=43&item=71|archive-date=14 September 2015|url-status=dead}}
Research activities
Lowy's HPV research, conducted in collaboration with John T. Schiller, has characterized the HPV oncoproteins E6 and E7.{{cite journal|last1=Androphy|first1=EJ|last2=Hubbert|first2=NL|last3=Schiller|first3=JT|last4=Lowy|first4=DR|title=Identification of the HPV-16 E6 protein from transformed mouse cells and human cervical carcinoma cell lines.|journal=The EMBO Journal|date=April 1987|volume=6|issue=4|pages=989–92|doi=10.1002/j.1460-2075.1987.tb04849.x|pmid=3036495|pmc=553493}}{{cite journal|last1=Hawley-Nelson|first1=P|last2=Vousden|first2=KH|last3=Hubbert|first3=NL|last4=Lowy|first4=DR|last5=Schiller|first5=JT|title=HPV16 E6 and E7 proteins cooperate to immortalize human foreskin keratinocytes.|journal=The EMBO Journal|date=1 December 1989|volume=8|issue=12|pages=3905–10|doi=10.1002/j.1460-2075.1989.tb08570.x|pmid=2555178|pmc=402081}}
Awards
- Nathan Davis Award, American Medical Association (2007){{cite web|url=http://www.aacr.org/Membership/Pages/FellowDetailsNoModal.aspx?ItemID=153#.Vag7bPkdddA|title=Douglas R. Lowy, MD|publisher=American Association for Cancer research |access-date=16 July 2015}}
- Service to America Medal, Partnership for Public Service (2007){{cite news |url=https://www.washingtonpost.com/wp-dyn/content/article/2007/09/09/AR2007090901634.html |newspaper=The Washington Post |date= September 10, 2007 |title=Work on Cervical Cancer Vaccine Puts NIH Duo in the Running for Major Award |first=Stephen |last=Barr|access-date=16 July 2015}}
- Humanitarian Award, American Skin Association (2007)
- Dorothy P. Landon-AACR Prize for Translational Cancer Research (2007)
- Novartis Prize for Clinical Immunology, Rio de Janeiro (2007){{cite web | title=Laureates | website=Novartis Prizes for Immunology | date=3 October 2011 | url=http://www.novartisimmunologyprizes.com/laureates/ | access-date=29 August 2018 | archive-url=https://web.archive.org/web/20180829175211/http://www.novartisimmunologyprizes.com/laureates/ | archive-date=29 August 2018 | url-status=dead }}
- Research and Hope Award for Academic or Public Research, National Cancer Institute (2013)
- Harrington Prize for Innovation in Medicine (2015){{cite web|url=http://www.ascopost.com/issues/march-10,-2015/douglas-r-lowy,-md,-receives-harrington-prize-for-innovation-in-medicine.aspx |title=Douglas R. Lowy, MD, Receives Harrington Prize for Innovation in Medicine |work= ASCO Post |date=March 10, 2015 |volume=6| issue=4 |access-date=16 July 2015}}{{cite journal|last1=Lowy|first1=Douglas R.|title=HPV vaccination to prevent cervical cancer and other HPV-associated disease: from basic science to effective interventions|journal=Journal of Clinical Investigation|date=4 January 2016|volume=126|issue=1|pages=5–11|doi=10.1172/JCI85446|pmid=26727228|pmc=4701560}}
- Lasker-DeBakey Clinical Medical Research Award (2017){{Cite web|url=http://www.laskerfoundation.org/awards/show/hpv-vaccines-cancer-prevention/#douglas-r-lowy|title=HPV vaccines for cancer prevention {{!}} The Lasker Foundation|last=Foundation|first=Lasker|website=The Lasker Foundation|language=en|access-date=2018-06-19}}
- Szent-Györgyi Prize for Progress in Cancer Research (2018) {{cite web|url=https://www.cancer.gov/news-events/press-releases/2018/lowy-schiller-szent-gyorgyi-prize|title=Szent-Györgyi Prize to honor NCI's Douglas R. Lowy and John T. Schiller |date=15 February 2018 |publisher=National Cancer Institute|access-date=4 October 2019}}
References
{{reflist|30em}}
External links
- [https://www.cancer.gov/about-nci/leadership/nci-deputy-director NCI Principal Deputy Director, Dr. Douglas R. Lowy]
- [https://ccr.cancer.gov/douglas-r-lowy?qt-staff_profile_tabs=0#qt-staff_profile_tabs Profile of Dr. Lowy], NCI Center for Cancer Research
{{Authority control}}
{{DEFAULTSORT:Lowy, Douglas R.}}
Category:Year of birth missing (living people)
Category:New York University Grossman School of Medicine alumni
Category:Members of the United States National Academy of Sciences
Category:National Institutes of Health people
Category:Amherst College alumni
Category:Place of birth missing (living people)
Category:Members of the National Academy of Medicine
Category:National Medal of Technology recipients
Category:Recipients of the Lasker–DeBakey Clinical Medical Research Award