Draft:Alexander Oraevsky

Alexander Oraevsky was born in the town of Vladimir, Russia. His father, Prof. Anatoly Nikolayevich Oraevsky (1934-2003), was a Russian physicist, member of the Russian Academy of Sciences and the Lenin Prize laureate, known for his work in quantum electronics, laser physics, and development of chemical lasers and gas-dynamic lasers.  

His mother was Iraida Sergeevna Oraevskaya (Timantseva) (1933 - 2020).

Alexander Oraevsky received his B.S. in Theoretical and Experimental Physics (1978) and M.S. in Ultrafast Laser Spectroscopy of Biomolecules (1980) from Moscow Engineering Physics Institute (presently National Research Nuclear University). In 1986, he completed his Ph.D. in Laser Spectroscopy, Photochemistry, and Biophysics from the USSR Academy of Sciences.

After completing his doctoral work, Oraevsky worked at the Institute of Spectroscopy of the Russian Academy of Sciences. In 1990, he immigrated to the United States, joining the Department of Electrical and Computer Engineering Department (Head Prof. Frank K. Tittel) at Rice University and simultaneously the Laser Biology Research Laboratory (Head Prof. Steven L. Jacques) at the University of Texas M.D. Anderson Cancer Center.  

In 1992, as a Whitaker Fellow, he joined the faculty at Rice University (Houston, Texas), and later served as Assistant Professor at the Department of Ophthalmology and Visual Sciences and Director of Optoacoustic Imaging Laboratory at the University of Texas Medical Branch (Galveston, Texas).

In 1996, he founded LaserSonix Technologies, a company dedicated to commercialization of optoacoustic imaging systems, assets of which have been sold in 2006 to Seno Medical Instruments (San Antonio, Texas). He later served as Vice-President of Research and Development at Fairway Medical Technologies (January 2002 - June 2010). As a Chief Scientific Officer at Seno Medical Instruments (January 2008 - May 2015), Alexander led the design and development of the clinical optoacoustic system combined with ultrasound that received the first regulatory approval by US FDA for diagnostic imaging of breast cancer in 2021{{Cite web |title=Premarket Approval (PMA) |url=https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfpma/pma.cfm?id=P200003 |access-date=2025-03-02 |website=www.accessdata.fda.gov}}.  

In 2010, Oraevsky founded TomoWave Laboratories, where he currently serves as CEO and CTO{{Cite web |title=Management - Tomowave - Optoacoustic imaging & Photoacoustic imaging |url=https://www.tomowave.com/about-us/management-team/ |access-date=2025-03-03 |website=Optoacoustic Tomography And Laser Ultrasound Systems |language=en-US}}. The company focuses on developing three-dimensional optoacoustic imaging systems for medical diagnostics and optoacoustic temperature imaging for monitoring minimally invasive hyperthermia of cancer.

Oraevsky is known for development of optoacoustic imaging technology. This technique visualizes biological tissue by detecting acoustic pressure profiles induced by molecular absorption of optical pulses. In 1997, he led the development of the first multichannel optoacoustic tomography system prototype with clinical applications{{Cite journal |title=Conference proceedings: Laser optoacoustic imaging for breast cancer diagnostics |url=https://www.spiedigitallibrary.org/conference-proceedings-of-spie/2979/1/Laser-optoacoustic-imaging-for-breast-cancer-diagnostics--limit-of/10.1117/12.280213.short |journal=SPIE Digital Library |doi=10.1117/12.280213}}.

In 2002, Oraevsky discovered strong optical absorption properties of gold nanorods tunable in the near-infrared spectral range. He proposed using plasmonic nanoparticles for optoacoustic imaging and later demonstrated detection of gold nanorods with optoacoustic imaging systems{{Cite journal |last1=Eghtedari |first1=Mohammad |last2=Oraevsky |first2=Alexander |last3=Copland |first3=John A. |last4=Kotov |first4=Nicholas A. |last5=Conjusteau |first5=Andre |last6=Motamedi |first6=Massoud |date=2007-07-01 |title=High Sensitivity of In Vivo Detection of Gold Nanorods Using a Laser Optoacoustic Imaging System |url=https://pubs.acs.org/doi/10.1021/nl070557d |journal=Nano Letters |volume=7 |issue=7 |pages=1914–1918 |doi=10.1021/nl070557d |pmid=17570730 |bibcode=2007NanoL...7.1914E |issn=1530-6984}}.   Throughout his career, Oraevsky has completed numerous research and development projects sponsored by the National Institutes of Health, Department of Defense, and various foundations. His notable developments include:

• The Laser Optoacoustic Imaging System (LOIS) for preclinical research in small animals{{Cite web |title=US patent US5840023A |url=https://patents.google.com/patent/US5840023A/en?oq=%C2%A0US5840023A%2c+Oraevsky%2c+Alexander+A.;+Jacques%2c+Steven+L.+%26+Esenaliev%2c+Rinat+O.%2c+%22Optoacoustic+imaging+for+medical+diagnosis%22%2c+issued+1998-11-24}}
• The Quantitative Optoacoustic Tomography System{{Cite patent|number=US20210018620A1|title=Quantitative Imaging System and Uses Thereof|gdate=2021-01-21|invent1=Oraevsky|inventor1-first=Alexander A.|url=https://patents.google.com/patent/US20210018620}} for clinical breast cancer research, enabling coregistered anatomical and functional imaging for medical diagnostics.

These systems have applications in imaging vasculature, measuring blood oxygen saturation, early detection of cancer, differentiating between benign and malignant breast tumors, and assessing cancer therapy efficacy. The National Cancer Institute sponsored{{Cite journal |last1=Oraevsky |first1=AA |last2=Clingman |first2=B |last3=Zalev |first3=J |last4=Stavros |first4=AT |last5=Yang |first5=WT |last6=Parikh |first6=JR |date=2018-08-31 |title=Clinical optoacoustic imaging combined with ultrasound for coregistered functional and anatomical mapping of breast tumors |journal=Photoacoustics |language=en |volume=12 |pages=30–45 |doi=10.1016/j.pacs.2018.08.003 |pmid=30306043 |pmc=6172480 |bibcode=2018PhAco..12...30O }} a pilot clinical study of his prototype system at MD Anderson Cancer Center.

At TomoWave Laboratories, Oraevsky leads the development of Symphony-3D breast imaging system{{Cite web |title=Symphony |url=https://www.tomowave.com/products/symphony/ |access-date=2025-03-03 |website=Optoacoustic Tomography And Laser Ultrasound Systems |language=en-US}} and Maestro-MD imaging system{{Cite web |title=Maestro Universal System |url=https://www.tomowave.com/products/maestro-universal-system/ |access-date=2025-03-03 |website=Optoacoustic Tomography And Laser Ultrasound Systems |language=en-US}}, which combines ultrasonic technology with optoacoustics for vascular imaging with applications including monitoring placental oxygen supply during pregnancy and assessing microvascular damage in diabetic feet.

In 1999, Oraevsky founded the international conference "Photons Plus Ultrasound: Imaging and Sensing"{{Cite web |title=Photons Plus Ultrasound: Imaging and Sensing 2025, Conference Details |url=https://spie.org/PW25B/conferencedetails/photons-plus-ultrasound |access-date=2025-03-03 |website=spie.org |language=en}}, which focuses on laser optoacoustic ultrasonic imaging. The conference is held annually as part of the SPIE Photonics West Symposium and has grown to become a major gathering in the field. File:Photonics West Conference 2025.jpg

Oraevsky also serves as Editor-in-Chief of "Photoacoustics"{{Cite web |title=Editorial board - Photoacoustics {{!}} ScienceDirect.com by Elsevier |url=https://www.sciencedirect.com/journal/photoacoustics/about/editorial-board |access-date=2025-03-03 |website=www.sciencedirect.com}}, an Elsevier journal dedicated to research in optoacoustic/photoacoustic imaging and sensing.

He holds an adjunct professor position{{Cite web |title=Alexander Oraevsky {{!}} UH Department of Biomedical Engineering |url=https://www.bme.uh.edu/faculty/oraevsky |access-date=2025-03-03 |website=www.bme.uh.edu |language=en}} at the Biomedical Engineering Department of the University of Houston (Texas).

Notable awards include:  

• Berthold Leibinger Innovations Prize{{Cite AV media |url=https://www.youtube.com/watch?v=rnXszBoSh1Y |title=Alexander A. Oraevsky - First Prize 2014 - English |date=2014-09-30 |last=LeibingerLaserPrize |access-date=2025-03-03 |via=YouTube}} (First Prize in 2014) for the invention and development of laser optoacoustic imaging systems 

• James Smith Award{{Cite web |title=Complete List of Prize Winners {{!}} Center for Advanced Diffusion-Wave and Photoacoustic Technologies - CADIPTCenter for Advanced Diffusion-Wave and Photoacoustic Technologies – CADIPT |url=https://cadipt.mie.utoronto.ca/ippa/complete-list-of-prize-winners/ |access-date=2025-03-03 |language=en-US}} from the International Photoacoustic and Photothermal Association (2015) for pioneering contributions to the field of biomedical photoacoustic imaging and the development of the first optoacoustic imaging systems.  
• Santander Chair of Excellence{{Cite web |title=Alexander Oraevsky {{!}} UC3M |url=https://www.uc3m.es/ss/Satellite/UC3MInstitucional/en/TextoMixta/1371239178317/ |archive-url=https://web.archive.org/web/20240621043646/https://www.uc3m.es/ss/Satellite/UC3MInstitucional/en/TextoMixta/1371239178317/ |archive-date=2024-06-21 |access-date=2025-03-03 |website=www.uc3m.es |language=en |url-status=live }} at the University Carlos III of Madrid (Spain), an honorary professorship position.
• Fellow of the International Society of Photonics Engineering{{Cite web |title=SPIE member page for Prof. Alexander A. Oraevsky |url=https://spie.org/profile/Alexander.Oraevsky-12466}} (SPIE, 2016) and Optica{{Cite web |title=Academia.edu - Find Research Papers, Topics, Researchers |url=https://tomowave.academia.edu/AlexanderOraevsky/CurriculumVitae |access-date=2025-03-03 |website=tomowave.academia.edu}} (Optical Society of America, 2021).  
• Member of Forbes Technology Council{{Cite web |title=Alexander Oraevsky {{!}} Chief Executive Officer and Chief Technology Officer - TomoWave |url=https://councils.forbes.com/profile/Alexander-Oraevsky-Chief-Executive-Officer-Chief-Technology-Officer-TomoWave/1847d88f-b034-4d85-970c-847471df6f0f |access-date=2025-03-03 |website=Forbes Technology Council |language=en}}

Oraevsky has been awarded more than 50 patents related to optoacoustic imaging and associated technologies{{Cite web |title=Alexander A. Oraevsky Inventions, Patents and Patent Applications - Justia Patents Search |url=https://patents.justia.com/inventor/alexander-a-oraevsky |access-date=2025-03-02 |website=patents.justia.com}}.He has authored or co-authored over 200 scientific publications that have been cited more than 14,750 times according to Google Scholar.{{Cite web |title=Alexander Oraevsky |url=https://scholar.google.com/citations?user=YBrsgg0AAAAJ&hl=en |access-date=2025-03-02 |website=scholar.google.com}} His research spans multiple disciplines including optoacoustic imaging, biomedical optics, laser physics, and medical diagnostics.

Alexander Oraevsky resides in Houston, Texas.

His recreational interests include badminton, SCUBA diving, fishing and boating{{Cite AV media |url=https://www.youtube.com/watch?si=VbjIGz2kV-VLSKwg&v=rnXszBoSh1Y&feature=youtu.be |title=Alexander A. Oraevsky - First Prize 2014 - English |date=2014-09-30 |last=LeibingerLaserPrize |access-date=2025-03-05 |via=YouTube}}.