Draft:Eliah G. Overbey

{{AFC comment|1=Yes, it's referenced. The article states in Ext Data Fig 1 that her work on the Inspiration4 crew is 92.4% of sequenced molecules, whereas NASA's database OSDR is 7.6%: https://www.nature.com/articles/s41586-024-07639-y}}

{{AFC comment|1=Please clean up "publications" (I'm not sure what's happening with all the formatting), place citations outside of periods, italicize things like the The New York Times and Science, and I will review. GoldRomean (talk) 02:15, 15 May 2025 (UTC)}}{{afc comment|GoldRomean's comments have been integrated into the article. GenomeNomad (talk) 02:19, 16 May 2025 (UTC)}}{{AFC comment|1=Is the stat re: SOMA generating "over 90% of all publicly available astronaut omics data" in the Nature study referenced? (IMO she meets notability; just want to ensure that the assertions of the article are verifiable.) JSFarman (talk) 03:33, 21 April 2025 (UTC)}}

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{{afc comment|Yes, it's referenced. The article states in Ext Data Fig 1 that her work on the Inspiration4 crew is 92.4% of sequenced molecules, whereas NASA's database OSDR is 7.6%: https://www.nature.com/articles/s41586-024-07639-y}}

Eliah G. Overbey is an assistant professor of Bioastronautics at the University of Austin and adjunct assistant professor of research in Computational Biomedicine at Weill Cornell Medicine.{{Cite web |title=Eliah Overbey |url=https://www.uaustin.org/people/eliah-overbey |access-date=2025-04-10 |website=www.uaustin.org |language=en}}{{Cite web |title=Overbey, Eliah |url=https://vivo.weill.cornell.edu/display/cwid-elo4004 |access-date=2025-04-10 |website=vivo.weill.cornell.edu}} She co-founded the Space Omics and Medical Atlas (SOMA), which has generated over 90% of all publicly available astronaut omics data.{{Cite journal |last1=Overbey |first1=Eliah G. |last2=Kim |first2=JangKeun |last3=Tierney |first3=Braden T. |last4=Park |first4=Jiwoon |last5=Houerbi |first5=Nadia |last6=Lucaci |first6=Alexander G. |last7=Garcia Medina |first7=Sebastian |last8=Damle |first8=Namita |last9=Najjar |first9=Deena |last10=Grigorev |first10=Kirill |last11=Afshin |first11=Evan E. |last12=Ryon |first12=Krista A. |last13=Sienkiewicz |first13=Karolina |last14=Patras |first14=Laura |last15=Klotz |first15=Remi |date=August 2024 |title=The Space Omics and Medical Atlas (SOMA) and international astronaut biobank |url=https://www.nature.com/articles/s41586-024-07639-y |journal=Nature |language=en |volume=632 |issue=8027 |pages=1145–1154 |doi=10.1038/s41586-024-07639-y |pmid=38862028 |bibcode=2024Natur.632.1145O |issn=1476-4687}}

{{Infobox scientist

| fields = Genomics, Bioastronautics

| workplaces = Weill Cornell Medicine,

University of Austin

| alma_mater = UC San Diego (BS),

University of Washington (PhD)

}}

Education

Overbey received her BS in Computer Science from UC San Diego and her PhD in Genome Sciences from the University of Washington. She performed her postdoctoral research in Christopher E. Mason's lab on a fellowship from NASA.{{Cite web |date=2020-09-18 |title=NASA Selects 18 Space Biology Research Proposals to Advance Scientific Knowledge of Life in Space and Foster Human Space Exploration - NASA Science |url=https://science.nasa.gov/science-research/biological-physical-sciences/spacebiologyprogramnraawardssep2020/?fbclid=IwAR0QHO6hmNjyYWE-hRTL5eVB1mz0UyM-NgAwfFgCqDdZ3xs6RXVZO9oknBY |access-date=2025-04-10 |language=en-US}} Overbey joined the University of Austin as a member of the founding faculty in 2024.{{Cite web |title=Meet the Scientist Launching the University of Austin Space Exploration Program, Professor Eliah Overbey |url=https://www.uaustin.org/blog/meet-the-scientist-launching-the-university-of-austin-space-exploration-program-professor-eliah-overbey |access-date=2025-04-10 |website=www.uaustin.org |language=en}}

Career

= Space Omics and Medical Atlas (SOMA) =

In 2021, Overbey led the collection of biospecimen samples from the Inspiration4 crew, collecting specimens from before, during, and after their mission.{{Cite journal |last1=Overbey |first1=Eliah G. |last2=Ryon |first2=Krista |last3=Kim |first3=JangKeun |last4=Tierney |first4=Braden T. |last5=Klotz |first5=Remi |last6=Ortiz |first6=Veronica |last7=Mullane |first7=Sean |last8=Schmidt |first8=Julian C. |last9=MacKay |first9=Matthew |last10=Damle |first10=Namita |last11=Najjar |first11=Deena |last12=Matei |first12=Irina |last13=Patras |first13=Laura |last14=Garcia Medina |first14=J. Sebastian |last15=Kleinman |first15=Ashley S. |date=2024-06-11 |title=Collection of biospecimens from the inspiration4 mission establishes the standards for the space omics and medical atlas (SOMA) |url=https://www.nature.com/articles/s41467-024-48806-z |journal=Nature Communications |language=en |volume=15 |issue=1 |pages=4964 |doi=10.1038/s41467-024-48806-z |pmid=38862509 |bibcode=2024NatCo..15.4964O |issn=2041-1723}} She then spearheaded efforts to generate and analyze various omics and molecular measurements, including whole genome, gene expression, chromatin accessibility, proteomic, metagenomic, and metatranscriptomic assays.{{Cite web |title=Space Omics and Medical Atlas Database Could Enhance the Health of Earthlings |url=https://www.technologynetworks.com/proteomics/news/space-omics-and-medical-atlas-database-could-enhance-the-health-of-earthlings-387686 |access-date=2025-04-10 |website=Proteomics & Metabolomics from Technology Networks |language=en}}{{Cite web |last=College |first=Weill Cornell Medical |title=Commercial astronauts shed light on flights' health impacts and create spaceflight atlas |url=https://medicalxpress.com/news/2024-06-commercial-astronauts-flights-health-impacts.html |access-date=2025-04-10 |website=medicalxpress.com |language=en}} This collection of data was made public in NASA's Open Science Data Repository in May 2024{{Cite journal |last1=Sanders |first1=Lauren M. |last2=Grigorev |first2=Kirill A. |last3=Scott |first3=Ryan T. |last4=Saravia-Butler |first4=Amanda M. |last5=Polo |first5=San-huei Lai |last6=Gilbert |first6=Rachel |last7=Overbey |first7=Eliah G. |last8=Kim |first8=JangKeun |last9=Mason |first9=Christopher E. |last10=Costes |first10=Sylvain V. |date=2024-05-14 |title=Inspiration4 data access through the NASA Open Science Data Repository |journal=npj Microgravity |language=en |volume=10 |issue=1 |page=56 |doi=10.1038/s41526-024-00393-5 |pmid=38744887 |pmc=11094041 |bibcode=2024npjMG..10...56S |issn=2373-8065}} and constitutes over 90% of publicly available astronaut omics data, which is necessary for the development of countermeasures for space colonization, including personalized medicine and pharmaceuticals.

The project gained national coverage with ranging interpretations. The New York Times and Science highlighted the vast changes that occurred during just 3 days in orbit{{Cite news |last=Chang |first=Kenneth |date=2024-06-12 |title=3 Days in Space Were Enough to Change 4 Astronauts' Bodies and Minds |url=https://www.nytimes.com/2024/06/12/science/astronauts-space-health-inspiration4-medical-records.html |access-date=2025-04-10 |work=The New York Times |language=en-US |issn=0362-4331}}{{Cite web |title=Astronauts face health risks—even on short trips in space |url=https://www.science.org/content/article/astronauts-face-health-risks-even-short-trips-space |access-date=2025-04-10 |website=www.science.org |language=en}}, while The Washington Post emphasized that scientists see no showstoppers for a mission to Mars.{{Cite news |last=Achenbach |first=Joel |date=2024-06-11 |title=Spaceflight is hard on humans, but scientists see no showstoppers |url=https://www.washingtonpost.com/science/2024/06/11/spaceflight-astronaut-human-body/ |newspaper=Washington Post}} SOMA also found evidence to support previous telomere lengthening results from the NASA Twin Study.{{Cite web |date=2024-06-14 |title=Why you shouldn't worry about invasive Joro spiders : Short Wave |url=https://www.npr.org/transcripts/1198910262 |access-date=2025-04-10 |website=NPR |language=en}} The Polaris Dawn crew have also participated in the study{{Cite web |last=Kraus |first=John |date=2022-10-24 |title=Polaris Dawn Selects 38 Science and Research Experiments to Advance Human Health and Space Exploration |url=https://polarisprogram.com/polaris-dawn-selects-38-science-and-research-experiments-to-advance-human-health-and-space-exploration/ |access-date=2025-04-10 |website=Polaris Program |language=en-US}}, but their data is not yet published. Notably, Jared Isaacman, the current nominee for NASA Administrator, was a research subject in both missions.

= Space Mission Development =

Overbey has been developing scientific competitions for the Space Exploration and Research Agency (SERA){{Cite news |last=Karlin |first=Susan |date=2024-11-15 |title=Blue Origin and SERA are creating 'a space agency for everyone' with a reality-style competition and TV series |url=https://www.fastcompany.com/91226683/blue-origin-sera-tv-series |archive-url=http://web.archive.org/web/20241116011631/https://www.fastcompany.com/91226683/blue-origin-sera-tv-series |archive-date=2024-11-16 |access-date=2025-04-10 |work=Fast Company |language=en-US}} and research missions for BioAstra{{Cite web |last=Skove |first=Sam |date=2025-03-20 |title=This nonprofit wants to send your twin into space |url=https://www.politico.com/newsletters/digital-future-daily/2025/03/20/this-non-profit-wants-to-send-your-twin-into-space-00240539 |access-date=2025-04-10 |website=POLITICO |language=en}}, where she serves as chief scientific officer.{{Cite web |title=About BioAstra {{!}} Driving Biotech and Healthcare Innovation |url=https://bioastra.org/about-us/ |access-date=2025-04-10 |website=bioastra.org/ |language=en-US}}

= University of Austin (UATX) =

In 2024, Overbey joined the University of Austin (UATX) as a member of the founding faculty, citing hostile work environments for Jewish students at other universities{{Cite news |title=University of Austin was founded on free speech. How's its first year? |url=https://www.csmonitor.com/USA/Education/2025/0226/university-of-austin-free-speech |access-date=2025-04-10 |work=Christian Science Monitor |issn=0882-7729}}, suppression of free speech on college campuses{{Cite web |date=2025-03-03 |title=Inside University of Austin's bold, anti-woke mission {{!}} Fox News Video |url=https://www.foxnews.com/video/6369564903112 |access-date=2025-04-10 |website=Fox News |language=en-US}}, and the desire to build new programs to train students for Mars colonization.{{Cite news |last=Coen |first=Susie |date=2024-10-27 |title=Inside the anti-woke university where you can't be cancelled |url=https://www.telegraph.co.uk/us/news/2024/10/27/inside-anti-woke-university-austin-you-cant-be-cancelled/ |access-date=2025-04-10 |work=The Telegraph |language=en-GB |issn=0307-1235}}

Publications

Foundational papers from the 2024 Nature SOMA collection.{{Cite web |title=Space Omics and Medical Atlas (SOMA) across orbits |url=https://preview.shorthand.com/uXfkBJxJ0FNkoOKq |access-date=2025-04-10 |website=www.nature.com |language=en}}

Overbey, E. G.; Kim, J.; Tierney, B. T.; et al. (2024). "The Space Omics and Medical Atlas (SOMA) and international astronaut biobank". Nature 632 (8027): 1145–1154. https://doi.org/10.1038/s41586-024-07639-y

Overbey, E. G.; Ryon, K.; Kim, J.; Tierney, B. T.; et al. (2024). "Collection of biospecimens from the Inspiration4 mission establishes the standards for the Space Omics and Medical Atlas (SOMA)". Nature Communications 15 (1): 1–14. https://doi.org/10.1038/s41467-024-48806-z

Jones, C. W.; Overbey, E. G.; Lacombe, J.; et al. (2024). "Molecular and physiological changes in the SpaceX Inspiration4 civilian crew". Nature 632 (8027): 1155–1164. https://doi.org/10.1038/s41586-024-07648-x