Duncan Odom
{{Short description|American research group leader}}
{{Infobox scientist
| name = Duncan T. Odom
| birth_name = Duncan Odom
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- DKFZ German Cancer Research Center
- Heidelberg University
- University of Cambridge
- Cancer Research UK
- Wellcome Trust Sanger Institute{{cite web|archive-url=https://web.archive.org/web/20160907141336/http://www.sanger.ac.uk/people/directory/odom-duncan|archive-date=2016-09-07|url=http://www.sanger.ac.uk/people/directory/odom-duncan|website=sanger.ac.uk|author=Anon|year=2016|title=Dr Duncan Odom: Associate Faculty|publisher=Wellcome Trust|url-status=dead}}
- Whitehead Institute}}
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- New College of Florida (BA)
- California Institute of Technology (PhD)}}
| thesis_title = The application of metallointercalators in recognition of and charge transport in nucleic acids
| thesis_url = https://doi.org/10.7907%2Fyz1f-w961
| thesis_year = 2001
| doctoral_advisor = Jacqueline Barton
| academic_advisors = Richard A. Young
| doctoral_students = Christina Ernst
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- Crick Lecture (2014)
- EMBO Member (2015){{cite web|author=Anon|year=2015|url=http://people.embo.org/profile/duncan-t-odom|website=people.embo.org|title=Duncan T. Odom|publisher=European Molecular Biology Organization|location=Heidelberg}}}}
Mary Lyon Award (2016)
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Duncan T. Odom is a research division head at the German Cancer Research Center (DKFZ) in Heidelberg, and a University Professor at Heidelberg University. Previously he was a research group leader at the Cancer Research UK Cambridge Institute (CRUK CI) at the University of Cambridge (2006-2022){{Google scholar id}}{{EuropePMC}} and an associate faculty member at the Wellcome Trust Sanger Institute (2011-2018).
Education
Odom was educated at the New College of Florida where he was awarded a Bachelor of Arts degree in Chemistry in 1995. He continued his study at California Institute of Technology (Caltech) where he was awarded a PhD in chemistry for research on DNA-binding metallo-intercalators supervised by Jacqueline Barton.Duncan Odom {{ORCID|0000-0001-6201-5599}}{{cite thesis |degree=PhD |first=Duncan T.|last=Odom |title=The application of metallointercalators in recognition of and charge transport in nucleic acids |publisher=California Institute of Technology |date=2001|doi=10.7907/yz1f-w961 |oclc=874759941 |id={{ProQuest|251012080}}|url=http://resolver.caltech.edu/CaltechTHESIS:03212014-095851500|website=caltech.edu}}
Career and research
After a period as a postdoctoral researcher{{Cite journal | pmid = 25001498| pmc = 4053951| year = 2014| last1 = Odom| first1 = Duncan T.|authorlink1=Duncan Odom| title = Survival strategies for choosing the right postdoc position| journal = Genome Biology| volume = 15| issue = 3| pages = 107| doi = 10.1186/gb4163
| doi-access = free}} {{open access}} in genetics and genomics at the Whitehead Institute in Cambridge, Massachusetts with Richard A. Young, he established his research group at the University of Cambridge in 2006. His research investigates how transcription and transcriptional regulation vary during evolution, and its implications for diseases such as cancer, using high throughput biology methods to investigate genome evolution.{{cite web|archive-url=https://web.archive.org/web/20170207043900/http://www.cruk.cam.ac.uk/research-groups/odom-group|archive-date=2017-02-07|url=http://www.cruk.cam.ac.uk/research-groups/odom-group|website=cruk.cam.ac.uk|title=Odom group: Transcription Regulation Laboratory|first=Duncan|last=Odom|year=2017|url-status=dead}}{{cite journal|last1=Villar|first1=Diego|last2=Berthelot|first2=Camille|last3=Aldridge|first3=Sarah|last4=Rayner|first4=Tim F.|last5=Lukk|first5=Margus|last6=Pignatelli|first6=Miguel|last7=Park|first7=Thomas J.|last8=Deaville|first8=Robert|last9=Erichsen|first9=Jonathan T.|last10=Jasinska|first10=Anna J.|last11=Turner|first11=James M.A.|last12=Bertelsen|first12=Mads F.|last13=Murchison|first13=Elizabeth P.|last14=Flicek|first14=Paul|last15=Odom|first15=Duncan T.|title=Enhancer Evolution across 20 Mammalian Species|journal=Cell|volume=160|issue=3|year=2015|pages=554–566|issn=0092-8674|doi=10.1016/j.cell.2015.01.006|pmid=25635462|pmc=4313353}}{{cite journal|last1=Stefflova|first1=Klara|last2=Thybert|first2=David|last3=Wilson|first3=Michael D.|last4=Streeter|first4=Ian|last5=Aleksic|first5=Jelena|last6=Karagianni|first6=Panagiota|last7=Brazma|first7=Alvis|last8=Adams|first8=David J.|last9=Talianidis|first9=Iannis|last10=Marioni|first10=John C.|last11=Flicek|first11=Paul|last12=Odom|first12=Duncan T.|title=Cooperativity and Rapid Evolution of Cobound Transcription Factors in Closely Related Mammals|pmid= 23911320|pmc=3732390 |journal=Cell|volume=154|issue=3|year=2013|pages=530–540|issn=0092-8674|doi=10.1016/j.cell.2013.07.007}} {{open access}}{{cite journal|last1=Ernst|first1=Christina|last2=Pike|first2=Jeremy|last3=Aitken|first3=Sarah J|last4=Long|first4=Hannah K|last5=Eling|first5=Nils|last6=Stojic|first6=Lovorka|last7=Ward|first7=Michelle C|last8=Connor|first8=Frances|last9=Rayner|first9=Timothy F|last10=Lukk|first10=Margus|last11=Klose|first11=Robert J|last12=Kutter|first12=Claudia|last13=Odom|first13=Duncan T|title=Successful transmission and transcriptional deployment of a human chromosome via mouse male meiosis|journal=eLife|volume=5|year=2016|issn=2050-084X|doi=10.7554/eLife.20235|pmid=27855777|pmc=5161449 |doi-access=free }} {{open access}} {{As of|2017}}, according to Google Scholar his most highly-cited papers have been published in Cell,{{cite journal |last1=Lee |first1=Tong Ihn |last2=Jenner |first2=Richard G. |last3=Boyer |first3=Laurie A. |author-link3=Laurie Boyer |last4=Guenther |first4=Matthew G. |last5=Levine |first5=Stuart S. |last6=Kumar |first6=Roshan M. |last7=Chevalier |first7=Brett |last8=Johnstone |first8=Sarah E. |last9=Cole |first9=Megan F. |last10=Isono |first10=Kyo-ichi |last11=Koseki |first11=Haruhiko |year=2006 |title=Control of Developmental Regulators by Polycomb in Human Embryonic Stem Cells |journal=Cell |volume=125 |issue=2 |pages=301–313 |doi=10.1016/j.cell.2006.02.043 |issn=0092-8674 |pmc=3773330 |pmid=16630818 |last12=Fuchikami |first12=Takuya |last13=Abe |first13=Kuniya |last14=Murray |first14=Heather L. |last15=Zucker |first15=Jacob P. |last16=Yuan |first16=Bingbing |last17=Bell |first17=George W. |last18=Herbolsheimer |first18=Elizabeth |last19=Hannett |first19=Nancy M. |last20=Sun |first20=Kaiming |last21=Odom |first21=Duncan T. |last22=Otte |first22=Arie P. |last23=Volkert |first23=Thomas L. |last24=Bartel |first24=David P. |last25=Melton |first25=Douglas A. |last26=Gifford |first26=David K. |last27=Jaenisch |first27=Rudolf |last28=Young |first28=Richard A. |authorlink28=Richard A. Young}} {{open access}} Chemical Reviews,{{cite journal|last1=Erkkila|first1=Kathryn E.|last2=Odom|first2=Duncan T.|last3=Barton|first3=Jacqueline K.|title=Recognition and Reaction of Metallointercalators with DNA|journal=Chemical Reviews|volume=99|issue=9|year=1999|pages=2777–2796|issn=0009-2665|doi=10.1021/cr9804341|pmid=11749500}} and Science.{{cite journal|last1=Lee|first1=T. I.|title=Transcriptional Regulatory Networks in Saccharomyces cerevisiae|journal=Science|volume=298|issue=5594|year=2002|pages=799–804|issn=0036-8075|doi=10.1126/science.1075090|pmid= 12399584|bibcode=2002Sci...298..799L|s2cid=4841222}}{{cite journal|last1=Odom|first1=D. T.|title=Control of Pancreas and Liver Gene Expression by HNF Transcription Factors|journal=Science|volume=303|issue=5662|year=2004|pages=1378–1381|issn=0036-8075|doi=10.1126/science.1089769|pmid= 14988562|pmc=3012624|bibcode=2004Sci...303.1378O}} {{open access}}
His research has been funded by the National Institute of Diabetes and Digestive and Kidney Diseases, the Alfred P. Sloan Foundation, the European Research Council (ERC),{{citation needed|date=November 2018}} the European Molecular Biology Organization (EMBO), the Wellcome Trust{{cite web|title=Investigator Awards in Science: people we've funded|archive-url=https://web.archive.org/web/20170426142635/https://wellcome.ac.uk/what-we-do/directories/investigator-awards-science-people-funded|archive-date=2017-04-26|url=https://wellcome.ac.uk/what-we-do/directories/investigator-awards-science-people-funded|website=wellcome.ac.uk|author=Anon|year=2017|publisher=Wellcome Trust|url-status=dead}} and Cancer Research UK. His former doctoral students include Christina Ernst.{{cite thesis|degree=PhD|publisher=University of Cambridge|url=https://www.repository.cam.ac.uk/handle/1810/278212|doi=10.17863/CAM.25556|title=Transcriptional and developmental consequences of aneuploidy during male meiosis|first= Christina|last=Ernst|date=2018|id={{EThOS|uk.bl.ethos.753466}}|website=cam.ac.uk|oclc=1065352558}} {{free access}}
=Awards and honours=
Odom was awarded the Crick Lecture by the Royal Society in 2014{{cite web|url=https://royalsociety.org/science-events-and-lectures/2014/francis-crick/|website=royalsociety.org|author=Anon|year=2014|publisher=Royal Society|title=Crick Lecture: Genetic control and the mammalian radiation|archive-url=https://web.archive.org/web/20170503164005/https://royalsociety.org/science-events-and-lectures/2014/francis-crick/|archive-date=2017-05-03|location=London|url-status=dead}}{{YouTube|id=kPsf3793Rhc|title=Event video: Genetic control and the mammalian radiation}} for his "pioneering work in the field of comparative functional genomics, which has changed our understanding of the evolution of mammalian transcriptional regulation." He was awarded EMBO Membership in 2015, and the Mary F. Lyon Medal from The Genetics Society in 2016.{{cite web|url=http://www.genetics.org.uk/medals-and-prizes/2015-winners/mary-lyon-medal/mary-lyon-medal-2016-dr-duncan-odum/|title=Mary Lyon Medal 2016 - Dr Duncan Odom - Genetics Society|website=Genetics.og.uk|access-date=28 November 2018}}
References
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Category:Year of birth missing (living people)
Category:American bioinformaticians
Category:Members of the European Molecular Biology Organization