EA-2012
{{one source|date=September 2018}}
{{Chembox
| Name = EA-2012
| ImageFile = Chemical structure of the EA-2012.png
| PIN = Bis(tetraphenylboranuide) N,N,N-trimethyl-3-({[(propan-2-yl)oxy](methylphosphonoyl)}oxy)-5-
| Section1 = {{Chembox Identifiers
| CASNo =
| SMILES = [B-](c1ccccc1)(c2ccccc2)(c3ccccc3)c4ccccc4.[B-](c1ccccc1)(c2ccccc2)(c3ccccc3)c4ccccc4.CC(C)OP(=O)(C)Oc5cc([N+](C)(C)C)cc(c5)OCCCCOc6cccc(c6)[N+](C)(C)C
| StdInChI=1S/C26H43N2O5P.2C24H20B/c1-21(2)32-34(9,29)33-26-19-23(28(6,7)8)18-25(20-26)31-16-11-10-15-30-24-14-12-13-22(17-24)27(3,4)5;2*1-5-13-21(14-6-1)25(22-15-7-2-8-16-22,23-17-9-3-10-18-23)24-19-11-4-12-20-24/h12-14,17-21H,10-11,15-16H2,1-9H3;2*1-20H/q+2;2*-1
| StdInChIKey=UBOLPSQXNCTHEF-UHFFFAOYSA-N
| PubChem =165360149
}}
| Section2 = {{Chembox Properties
| C=74|H=83|B=2|N=2|O=5|P=1
| Appearance = Solid
| MeltingPtC = 171-172
| Solubility = Insoluble
| SolubleOther = Soluble in acetone
}}
| Section3 = {{Chembox Hazards
| MainHazards = Extremely toxic
| LD50 = 93 μg/kg (Rats, IV)
17 μg/kg (Rabbits, IV)
}}
}}
EA-2012 is an extremely toxic organophosphate nerve agent. It is an extremely potent acetylcholinesterase inhibitor that is resistant to atropine and oxime treatment.{{cite web |title=Toxic phosphorus compounds |url=https://patents.google.com/patent/US3900535A/en}}
See also
References
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{{Chemical agents}}
{{Neurotoxins}}
{{Acetylcholine metabolism and transport modulators}}
Category:Organophosphate nerve agents
Category:Acetylcholinesterase inhibitors
Category:Quaternary ammonium compounds
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