EAF1
{{Short description|Protein-coding gene in the species Homo sapiens}}
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ELL-associated factor 1 is a protein that, in humans, is encoded by the EAF1 gene.{{cite journal | vauthors = Simone F, Polak PE, Kaberlein JJ, Luo RT, Levitan DA, Thirman MJ | title = EAF1, a novel ELL-associated factor that is delocalized by expression of the MLL-ELL fusion protein | journal = Blood | volume = 98 | issue = 1 | pages = 201–9 | date = July 2001 | pmid = 11418481 | doi = 10.1182/blood.V98.1.201 | s2cid = 2577367 }}{{cite web | title = Entrez Gene: EAF1 ELL associated factor 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=85403}} It is part of the EAF family of proteins.
References
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Further reading
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- {{cite journal | vauthors = Polak PE, Simone F, Kaberlein JJ, Luo RT, Thirman MJ | title = ELL and EAF1 are Cajal body components that are disrupted in MLL-ELL leukemia | journal = Molecular Biology of the Cell | volume = 14 | issue = 4 | pages = 1517–28 | date = April 2003 | pmid = 12686606 | pmc = 153119 | doi = 10.1091/mbc.E02-07-0394 }}
- {{cite journal | vauthors = Kong SE, Banks CA, Shilatifard A, Conaway JW, Conaway RC | title = ELL-associated factors 1 and 2 are positive regulators of RNA polymerase II elongation factor ELL | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 102 | issue = 29 | pages = 10094–8 | date = July 2005 | pmid = 16006523 | pmc = 1177379 | doi = 10.1073/pnas.0503017102 | bibcode = 2005PNAS..10210094K | doi-access = free }}
- {{cite journal | vauthors = Xiao W, Jiang F, Wang Z | title = ELL binding regulates U19/Eaf2 intracellular localization, stability, and transactivation | journal = The Prostate | volume = 66 | issue = 1 | pages = 1–12 | date = January 2006 | pmid = 16114057 | doi = 10.1002/pros.20309 | s2cid = 32749490 }}
- {{cite journal | vauthors = Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M | title = Global, in vivo, and site-specific phosphorylation dynamics in signaling networks | journal = Cell | volume = 127 | issue = 3 | pages = 635–48 | date = November 2006 | pmid = 17081983 | doi = 10.1016/j.cell.2006.09.026 | s2cid = 7827573 | doi-access = free }}
- {{cite journal | vauthors = Jiang F, Ai J, Xiao W, Wang Z | title = FB1, an E2A fusion partner in childhood leukemia, interacts with U19/EAF2 and inhibits its transcriptional activity | journal = Cancer Letters | volume = 253 | issue = 2 | pages = 265–72 | date = August 2007 | pmid = 17395368 | pmc = 1989770 | doi = 10.1016/j.canlet.2007.02.003 }}
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