EGR4
{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
Early growth response protein 4 (EGR-4), also known as AT133, is a protein that in humans is encoded by the EGR4 gene.{{cite web | title = Entrez Gene: early growth response 4| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1961}}
EGR-4 is a member of the early growth response (EGF) family of zinc finger transcription factors.
References
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Further reading
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- {{cite journal |vauthors=Crosby SD, Veile RA, Donis-Keller H |title=Neural-specific expression, genomic structure, and chromosomal localization of the gene encoding the zinc-finger transcription factor NGFI-C. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=89 |issue= 10 |pages= 4739–43 |year= 1992 |pmid= 1584812 |doi= 10.1073/pnas.89.10.4739 |pmc=49159|bibcode=1992PNAS...89.4739C |display-authors=etal|doi-access=free }}
- {{cite journal |vauthors=Hillier LW, Graves TA, Fulton RS |title=Generation and annotation of the DNA sequences of human chromosomes 2 and 4. |journal=Nature |volume=434 |issue= 7034 |pages= 724–31 |year= 2005 |pmid= 15815621 |doi= 10.1038/nature03466 |bibcode=2005Natur.434..724H |display-authors=etal|doi-access=free }}
- {{cite journal | vauthors = Müller HJ, Skerka C, Bialonski A, Zipfel PF | title = Clone pAT 133 identifies a gene that encodes another human member of a class of growth factor-induced genes with almost identical zinc-finger domains | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 88 | issue = 22 | pages = 10079–83 |date=November 1991 | pmid = 1658795 | pmc = 52871 | doi = 10.1073/pnas.88.22.10079| bibcode = 1991PNAS...8810079M | doi-access = free }}
- {{cite journal |vauthors=Decker EL, Nehmann N, Kampen E |title=Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression. |journal=Nucleic Acids Res. |volume=31 |issue= 3 |pages= 911–21 |year= 2003 |pmid= 12560487 |doi= 10.1093/nar/gkg186 |pmc=149206|display-authors=etal}}
- {{cite journal |vauthors=Liu BC, Zhang J, Wang L |title=No association between EGR gene family polymorphisms and schizophrenia in the Chinese population. |journal=Prog. Neuropsychopharmacol. Biol. Psychiatry |volume=34 |issue= 3 |pages= 506–9 |year= 2010 |pmid= 20144677 |doi= 10.1016/j.pnpbp.2010.02.005 |s2cid=207409159 |display-authors=etal}}
- {{cite journal |vauthors=Kimura K, Wakamatsu A, Suzuki Y |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 |pmc=1356129|display-authors=etal}}
- {{cite journal |vauthors=Holst C, Skerka C, Lichter P |title=Genomic organization, chromosomal localization and promoter function of the human zinc-finger gene pAT133. |journal=Hum. Mol. Genet. |volume=2 |issue= 4 |pages= 367–72 |year= 1993 |pmid= 8504297 |doi= 10.1093/hmg/2.4.367|display-authors=etal}}
- {{cite journal |vauthors=Crosby SD, Puetz JJ, Simburger KS |title=The early response gene NGFI-C encodes a zinc finger transcriptional activator and is a member of the GCGGGGGCG (GSG) element-binding protein family. |journal=Mol. Cell. Biol. |volume=11 |issue= 8 |pages= 3835–41 |year= 1991 |pmid= 2072895 |doi= 10.1128/MCB.11.8.3835|pmc=361165|display-authors=etal}}
- {{cite journal |vauthors=Hadziselimovic F, Hadziselimovic NO, Demougin P |title=EGR4 is a master gene responsible for fertility in cryptorchidism. |journal=Sex Dev |volume=3 |issue= 5 |pages= 253–63 |year= 2009 |pmid= 19828938 |doi= 10.1159/000249147 |display-authors=etal|doi-access=free }}
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{{Transcription factors|g2}}
Category:Molecular neuroscience
Category:Transcription factors
{{gene-2-stub}}