EIF3H
{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
Eukaryotic translation initiation factor 3 subunit H (eIF3h) is a protein that in humans is encoded by the EIF3H gene.{{cite journal | vauthors = Asano K, Vornlocher HP, Richter-Cook NJ, Merrick WC, Hinnebusch AG, Hershey JW | title = Structure of cDNAs encoding human eukaryotic initiation factor 3 subunits. Possible roles in RNA binding and macromolecular assembly | journal = J. Biol. Chem. | volume = 272 | issue = 43 | pages = 27042–52 | date = Nov 1997 | pmid = 9341143 | doi = 10.1074/jbc.272.43.27042 | doi-access = free }}{{cite web | title = Entrez Gene: EIF3S3 eukaryotic translation initiation factor 3, subunit 3 gamma, 40kDa| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8667}}
Interactions
eIF3h has been shown to interact with eIF3a.{{cite journal | vauthors = Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D | title = Large-scale mapping of human protein-protein interactions by mass spectrometry | journal = Mol. Syst. Biol. | volume = 3 | issue = 1 | pages = 89 | year = 2007 | pmid = 17353931 | pmc = 1847948 | doi = 10.1038/msb4100134 }}{{cite journal | vauthors = Mayeur GL, Fraser CS, Peiretti F, Block KL, Hershey JW | title = Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3 | journal = Eur. J. Biochem. | volume = 270 | issue = 20 | pages = 4133–9 | date = Oct 2003 | pmid = 14519125 | doi = 10.1046/j.1432-1033.2003.03807.x | doi-access = free }}{{cite journal | vauthors = Block KL, Vornlocher HP, Hershey JW | title = Characterization of cDNAs encoding the p44 and p35 subunits of human translation initiation factor eIF3 | journal = J. Biol. Chem. | volume = 273 | issue = 48 | pages = 31901–8 | date = Nov 1998 | pmid = 9822659 | doi = 10.1074/jbc.273.48.31901 | doi-access = free }}
See also
References
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Further reading
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- {{cite journal | vauthors = Maruyama K, Sugano S | title = Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides | journal = Gene | volume = 138 | issue = 1–2 | pages = 171–4 | year = 1994 | pmid = 8125298 | doi = 10.1016/0378-1119(94)90802-8 }}
- {{cite journal | vauthors = Asano K, Kinzy TG, Merrick WC, Hershey JW | title = Conservation and diversity of eukaryotic translation initiation factor eIF3 | journal = J. Biol. Chem. | volume = 272 | issue = 2 | pages = 1101–9 | year = 1997 | pmid = 8995409 | doi = 10.1074/jbc.272.2.1101 | doi-access = free }}
- {{cite journal | vauthors = Méthot N, Rom E, Olsen H, Sonenberg N | title = The human homologue of the yeast Prt1 protein is an integral part of the eukaryotic initiation factor 3 complex and interacts with p170 | journal = J. Biol. Chem. | volume = 272 | issue = 2 | pages = 1110–6 | year = 1997 | pmid = 8995410 | doi = 10.1074/jbc.272.2.1110 | doi-access = free }}
- {{cite journal | vauthors = Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S | title = Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library | journal = Gene | volume = 200 | issue = 1–2 | pages = 149–56 | year = 1997 | pmid = 9373149 | doi = 10.1016/S0378-1119(97)00411-3 }}
- {{cite journal | vauthors = Block KL, Vornlocher HP, Hershey JW | title = Characterization of cDNAs encoding the p44 and p35 subunits of human translation initiation factor eIF3 | journal = J. Biol. Chem. | volume = 273 | issue = 48 | pages = 31901–8 | year = 1998 | pmid = 9822659 | doi = 10.1074/jbc.273.48.31901 | doi-access = free }}
- {{cite journal | vauthors = Saramäki O, Willi N, Bratt O, Gasser TC, Koivisto P, Nupponen NN, Bubendorf L, Visakorpi T | title = Amplification of EIF3S3 gene is associated with advanced stage in prostate cancer | journal = Am. J. Pathol. | volume = 159 | issue = 6 | pages = 2089–94 | year = 2001 | pmid = 11733359 | pmc = 1850612 | doi = 10.1016/S0002-9440(10)63060-X }}
- {{cite journal | vauthors = Morris JA, Kandpal G, Ma L, Austin CP | title = DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation | journal = Hum. Mol. Genet. | volume = 12 | issue = 13 | pages = 1591–608 | year = 2003 | pmid = 12812986 | doi = 10.1093/hmg/ddg162 | doi-access = free }}
- {{cite journal | vauthors = Mayeur GL, Fraser CS, Peiretti F, Block KL, Hershey JW | title = Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3 | journal = Eur. J. Biochem. | volume = 270 | issue = 20 | pages = 4133–9 | year = 2003 | pmid = 14519125 | doi = 10.1046/j.1432-1033.2003.03807.x | doi-access = free }}
- {{cite journal | vauthors = Okamoto H, Yasui K, Zhao C, Arii S, Inazawa J | title = PTK2 and EIF3S3 genes may be amplification targets at 8q23-q24 and are associated with large hepatocellular carcinomas | journal = Hepatology | volume = 38 | issue = 5 | pages = 1242–9 | year = 2003 | pmid = 14578863 | doi = 10.1053/jhep.2003.50457 | s2cid = 21888517 | doi-access = free }}
- {{cite journal | vauthors = Savinainen KJ, Linja MJ, Saramäki OR, Tammela TL, Chang GT, Brinkmann AO, Visakorpi T | title = Expression and copy number analysis of TRPS1, EIF3S3 and MYC genes in breast and prostate cancer | journal = Br. J. Cancer | volume = 90 | issue = 5 | pages = 1041–6 | year = 2004 | pmid = 14997205 | pmc = 2409619 | doi = 10.1038/sj.bjc.6601648 }}
- {{cite journal | vauthors = Savinainen KJ, Helenius MA, Lehtonen HJ, Visakorpi T | title = Overexpression of EIF3S3 promotes cancer cell growth | journal = Prostate | volume = 66 | issue = 11 | pages = 1144–50 | year = 2006 | pmid = 16652384 | doi = 10.1002/pros.20452 | s2cid = 2281409 }}
- {{cite journal | vauthors = Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M | title = Global, in vivo, and site-specific phosphorylation dynamics in signaling networks | journal = Cell | volume = 127 | issue = 3 | pages = 635–48 | year = 2006 | pmid = 17081983 | doi = 10.1016/j.cell.2006.09.026 | s2cid = 7827573 | doi-access = free }}
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External links
- {{PDBe-KB2|O15372|Eukaryotic translation initiation factor 3 subunit H}}
{{Initiation factors}}
{{gene-8-stub}}