EIF5A2

{{Short description|Protein-coding gene in the species Homo sapiens}}

{{Infobox_gene}}

Eukaryotic translation initiation factor 5A-2 is a protein that in humans is encoded by the EIF5A2 gene.{{cite web | title = Entrez Gene: EIF5A2 eukaryotic translation initiation factor 5A2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=56648}}

References

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Further reading

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  • {{cite journal | vauthors=Jenkins ZA, Hååg PG, Johansson HE |title=Human eIF5A2 on chromosome 3q25-q27 is a phylogenetically conserved vertebrate variant of eukaryotic translation initiation factor 5A with tissue-specific expression. |journal=Genomics |volume=71 |issue= 1 |pages= 101–9 |year= 2001 |pmid= 11161802 |doi= 10.1006/geno.2000.6418 }}
  • {{cite journal | vauthors=Guan XY, Sham JS, Tang TC |title=Isolation of a novel candidate oncogene within a frequently amplified region at 3q26 in ovarian cancer. |journal=Cancer Research |volume=61 |issue= 9 |pages= 3806–9 |year= 2001 |pmid= 11325856 |display-authors=etal}}
  • {{cite journal | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proceedings of the National Academy of Sciences of the United States of America |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |display-authors=etal|doi-access=free }}
  • {{cite journal | vauthors=Clement PM, Henderson CA, Jenkins ZA, Smit-McBride Z, Wolff EC, Hershey JW, Park MH, Johansson HE |title=Identification and characterization of eukaryotic initiation factor 5A-2. |journal=European Journal of Biochemistry |volume=270 |issue= 21 |pages= 4254–63 |year= 2003 |pmid= 14622290 |doi=10.1046/j.1432-1033.2003.03806.x |doi-access=free }}
  • {{cite journal | vauthors=Guan XY, Fung JM, Ma NF |title=Oncogenic role of eIF-5A2 in the development of ovarian cancer. |journal=Cancer Res. |volume=64 |issue= 12 |pages= 4197–200 |year= 2004 |pmid= 15205331 |doi= 10.1158/0008-5472.CAN-03-3747 |s2cid=6823741 |display-authors=etal|doi-access= }}
  • {{cite journal | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Research |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |display-authors=etal}}
  • {{cite journal | vauthors=Christensen GL, Ivanov IP, Atkins JF |title=Screening the SPO11 and EIF5A2 genes in a population of infertile men. |journal=Fertility and Sterility |volume=84 |issue= 3 |pages= 758–60 |year= 2005 |pmid= 16169419 |doi= 10.1016/j.fertnstert.2005.03.053 |display-authors=etal|doi-access=free }}
  • {{cite journal | vauthors=Clement PM, Johansson HE, Wolff EC, Park MH |title=Differential expression of eIF5A-1 and eIF5A-2 in human cancer cells. |journal=The FEBS Journal |volume=273 |issue= 6 |pages= 1102–14 |year= 2006 |pmid= 16519677 |doi= 10.1111/j.1742-4658.2006.05135.x |pmc=4406228 }}
  • {{cite journal | vauthors=Xie D, Ma NF, Pan ZZ, Wu HX, Liu YD, Wu GQ, Kung HF, Guan XY |title=Overexpression of EIF-5A2 is associated with metastasis of human colorectal carcinoma. |journal=Human Pathology |volume=39 |issue= 1 |pages= 80–6|year= 2008 |pmid= 17949776 |doi= 10.1016/j.humpath.2007.05.011 }}
  • {{cite journal | vauthors=Yang GF, Xie D, Liu JH, Luo JH, Li LJ, Hua WF, Wu HM, Kung HF, Zeng YX, Guan XY |title=Expression and amplification of eIF-5A2 in human epithelial ovarian tumors and overexpression of EIF-5A2 is a new independent predictor of outcome in patients with ovarian carcinoma. |journal=Gynecol. Oncol. |volume=112 |issue= 2 |pages= 314–8 |year= 2009 |pmid= 19054548 |doi= 10.1016/j.ygyno.2008.10.024 }}
  • {{cite journal | vauthors=Chen W, Luo JH, Hua WF, Zhou FJ, Lin MC, Kung HF, Zeng YX, Guan XY, Xie D |title=Overexpression of EIF-5A2 is an independent predictor of outcome in patients of urothelial carcinoma of the bladder treated with radical cystectomy. |journal=Cancer Epidemiology, Biomarkers & Prevention |volume= 18|issue= 2 |pages= 400–8 |year= 2009 |pmid= 19155439 |doi= 10.1158/1055-9965.EPI-08-0754 |s2cid=9907553 |doi-access= }}
  • {{cite journal | vauthors=Luo JH, Hua WF, Rao HL, Liao YJ, Kung HF, Zeng YX, Guan XY, Chen W, Xie D |title=Overexpression of EIF-5A2 predicts tumor recurrence and progression in pTa/pT1 urothelial carcinoma of the bladder. |journal=Cancer Science |volume=100 |issue= 5 |pages= 896–902 |year= 2009 |pmid= 19298601 |doi= 10.1111/j.1349-7006.2009.01126.x |s2cid=23225065 |doi-access= |pmc= 11158472 }}
  • {{cite journal | vauthors=Tang DJ, Dong SS, Ma NF, Xie D, Chen L, Fu L, Lau SH, Li Y, Li Y, Guan XY |title=Overexpression of eukaryotic initiation factor 5A2 enhances cell motility and promotes tumor metastasis in hepatocellular carcinoma. |journal=Hepatology |volume=51 |issue= 4 |pages= 1255–63 |year= 2010 |pmid= 20112425 |doi= 10.1002/hep.23451 |s2cid=5328378 |doi-access=free }}
  • {{cite journal | vauthors=Chen M, Huang JD, Deng HK, Dong S, Deng W, Tsang SL, Huen MS, Chen L, Zan T, Zhu GX, Guan XY |title=Overexpression of eIF-5A2 in mice causes accelerated organismal aging by increasing chromosome instability. |journal=BMC Cancer |volume=11 |pages= 199 |year= 2011 |pmid= 21612665 |doi= 10.1186/1471-2407-11-199 |pmc=3118894 |doi-access=free }}
  • {{cite journal | vauthors=He LR, Zhao HY, Li BK, Liu YH, Liu MZ, Guan XY, Bian XW, Zeng YX, Xie D |title=Overexpression of eIF5A-2 is an adverse prognostic marker of survival in stage I non-small cell lung cancer patients. |journal=International Journal of Cancer |volume=129 |issue= 1 |pages= 143–50 |year= 2011 |pmid= 20830705 |doi= 10.1002/ijc.25669 |s2cid=205942112 |doi-access=free }}

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{{Initiation factors}}

{{gene-3-stub}}