ELF2

{{Short description|Protein-coding gene in the species Homo sapiens}}

E74-like factor 2 (ELF2), formerly known as new Ets-related factor (NERF), is an ETS family transcription factor.{{cite journal | vauthors = Oettgen P, Akbarali Y, Boltax J, Best J, Kunsch C, Libermann TA | title = Characterization of NERF, a novel transcription factor related to the Ets factor ELF-1 | journal = Mol. Cell. Biol. | volume = 16 | issue = 9 | pages = 5091–106 |date=September 1996 | pmid = 8756667 | pmc = 231510 | doi = 10.1128/MCB.16.9.5091}} In humans this protein is encoded by the ELF2 gene.{{cite web | title = Entrez Gene: ELF2 E74-like factor 2 (ets domain transcription factor)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1998}}

References

{{cite journal | vauthors=Wilkinson DA, Neale GA, Mao S |title=Elf-2, a rhombotin-2 binding ets transcription factor: discovery and potential role in T cell leukemia. |journal=Leukemia |volume=11 |issue= 1 |pages= 86–96 |year= 1997 |pmid= 9001422 |doi=10.1038/sj.leu.2400516 |display-authors=etal|doi-access=free }}
{{cite journal | vauthors=Mao S, Frank RC, Zhang J |title=Functional and physical interactions between AML1 proteins and an ETS protein, MEF: implications for the pathogenesis of t(8;21)-positive leukemias. |journal=Mol. Cell. Biol. |volume=19 |issue= 5 |pages= 3635–44 |year= 1999 |pmid= 10207087 |doi= 10.1128/mcb.19.5.3635| pmc=84165 |display-authors=etal}}
{{cite journal | vauthors=Christensen RA, Fujikawa K, Madore R |title=NERF2, a member of the Ets family of transcription factors, is increased in response to hypoxia and angiopoietin-1: a potential mechanism for Tie2 regulation during hypoxia. |journal=J. Cell. Biochem. |volume=85 |issue= 3 |pages= 505–15 |year= 2002 |pmid= 11967990 |doi= 10.1002/jcb.10148 |s2cid=36902890 |display-authors=etal}}
{{cite journal | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |display-authors=etal|doi-access=free }}
{{cite journal | vauthors=Cho JY, Akbarali Y, Zerbini LF |title=Isoforms of the Ets transcription factor NERF/ELF-2 physically interact with AML1 and mediate opposing effects on AML1-mediated transcription of the B cell-specific blk gene. |journal=J. Biol. Chem. |volume=279 |issue= 19 |pages= 19512–22 |year= 2004 |pmid= 14970218 |doi= 10.1074/jbc.M309074200 |display-authors=etal|doi-access=free }}
{{cite journal | vauthors=Beausoleil SA, Jedrychowski M, Schwartz D |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101 | pmc=514446 |bibcode=2004PNAS..10112130B |display-authors=etal|doi-access=free }}
{{cite journal | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |display-authors=etal}}
{{cite journal | vauthors=Zhang B, Tomita Y, Qiu Y |title=E74-like factor 2 regulates valosin-containing protein expression. |journal=Biochem. Biophys. Res. Commun. |volume=356 |issue= 3 |pages= 536–41 |year= 2007 |pmid= 17368566 |doi= 10.1016/j.bbrc.2007.02.160 |display-authors=etal}}

Category:Transcription factors

ELF2

References

Further reading