ELS

• Emerson Literary Society, a social society at Hamilton College
• Empirical legal studies
• English Language School, Dubai
• Europeesche Lagere School, a school system in the colonial Dutch East Indies
• Expeditionary learning schools, in the United States

• Early Life Stage test, a chronic toxicity test
• Eaton–Lambert syndrome, a muscle disease
• Editor in the Life Sciences, a professional certification
• ELS cotton (Gossypium barbadense), a species of cotton
• Encyclopedia of Life Sciences, an online encyclopedia

• Els (given name), a feminine given name short for Elisabeth
• Ernie Els (born 1969), South African golfer
• Jurie Els, South African singer

• Electrophoretic light scattering
• Engineered Lifting Systems & Equipment, a Canadian manufacturing company
• Ensemble de Lancement Soyouz, a launch pad at Guiana Space Centre
• Extreme Loading for Structures, structural analysis software
• Emergency Light System, emergency lighting installed on emergency vehicles

• Els (Streu), a river in Germany
• East London Airport, in South Africa
• Edinburgh Labour Students, a student wing of the Labour Party of the United Kingdom
• Elsternwick railway station, Melbourne
• Equidistant letter sequence, a bible code method
• Escanaba and Lake Superior Railroad, in the United States
• Evangelical Lutheran Synod, a US-based Protestant Christian denomination
• Liberation Army of the South ({{langx|es|Ejército Libertador del Sur|link=no}}), an armed group active during the Mexican Revolution

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