EP400
{{Short description|Protein-coding gene in humans}}
{{Infobox_gene}}
E1A-binding protein p400 is a protein that in humans is encoded by the EP400 gene.{{cite journal | vauthors = Margolis RL, Abraham MR, Gatchell SB, Li SH, Kidwai AS, Breschel TS, Stine OC, Callahan C, McInnis MG, Ross CA | title = cDNAs with long CAG trinucleotide repeats from human brain | journal = Hum Genet | volume = 100 | issue = 1 | pages = 114–22 |date=Jul 1997 | pmid = 9225980 | doi =10.1007/s004390050476 | s2cid = 25999127 }}{{cite journal | vauthors = Fuchs M, Gerber J, Drapkin R, Sif S, Ikura T, Ogryzko V, Lane WS, Nakatani Y, Livingston DM | title = The p400 complex is an essential E1A transformation target | journal = Cell | volume = 106 | issue = 3 | pages = 297–307 |date=Aug 2001 | pmid = 11509179 | doi =10.1016/S0092-8674(01)00450-0 | s2cid = 15634637 | doi-access = free }}{{cite web | title = Entrez Gene: EP400 E1A binding protein p400| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=57634}}
Interactions
EP400 has been shown to interact with Transformation/transcription domain-associated protein, RuvB-like 1 and Myc.
References
{{reflist}}
Further reading
{{refbegin | 2}}
- {{cite journal | vauthors=Doyon Y, Côté J |title=The highly conserved and multifunctional NuA4 HAT complex. |journal=Curr. Opin. Genet. Dev. |volume=14 |issue= 2 |pages= 147–54 |year= 2004 |pmid= 15196461 |doi= 10.1016/j.gde.2004.02.009 }}
- {{cite journal | vauthors=Nagase T, Kikuno R, Ishikawa K |title=Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=7 |issue= 2 |pages= 143–50 |year= 2000 |pmid= 10819331 |doi=10.1093/dnares/7.2.143 |display-authors=etal|doi-access=free }}
- {{cite journal | vauthors=Nagase T, Nakayama M, Nakajima D |title=Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=8 |issue= 2 |pages= 85–95 |year= 2001 |pmid= 11347906 |doi=10.1093/dnares/8.2.85 |display-authors=etal|doi-access=free }}
- {{cite journal | vauthors=Nakayama M, Kikuno R, Ohara O |title=Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs. |journal=Genome Res. |volume=12 |issue= 11 |pages= 1773–84 |year= 2003 |pmid= 12421765 |doi= 10.1101/gr.406902 | pmc=187542 }}
- {{cite journal | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |display-authors=etal|doi-access=free }}
- {{cite journal | vauthors=Cai Y, Jin J, Tomomori-Sato C |title=Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex. |journal=J. Biol. Chem. |volume=278 |issue= 44 |pages= 42733–6 |year= 2003 |pmid= 12963728 |doi= 10.1074/jbc.C300389200 |display-authors=etal|doi-access=free }}
- {{cite journal | vauthors=Ota T, Suzuki Y, Nishikawa T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=etal|doi-access=free }}
- {{cite journal | vauthors=Doyon Y, Selleck W, Lane WS |title=Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans. |journal=Mol. Cell. Biol. |volume=24 |issue= 5 |pages= 1884–96 |year= 2004 |pmid= 14966270 |doi=10.1128/MCB.24.5.1884-1896.2004 | pmc=350560 |display-authors=etal}}
- {{cite journal | vauthors=Beausoleil SA, Jedrychowski M, Schwartz D |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101 | pmc=514446 |bibcode=2004PNAS..10112130B |display-authors=etal|doi-access=free }}
- {{cite journal | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |display-authors=etal}}
- {{cite journal | vauthors=Chan HM, Narita M, Lowe SW, Livingston DM |title=The p400 E1A-associated protein is a novel component of the p53 --> p21 senescence pathway. |journal=Genes Dev. |volume=19 |issue= 2 |pages= 196–201 |year= 2005 |pmid= 15655109 |doi= 10.1101/gad.1280205 | pmc=545875 }}
- {{cite journal | vauthors=Samuelson AV, Narita M, Chan HM |title=p400 is required for E1A to promote apoptosis. |journal=J. Biol. Chem. |volume=280 |issue= 23 |pages= 21915–23 |year= 2005 |pmid= 15741165 |doi= 10.1074/jbc.M414564200 |display-authors=etal|doi-access=free }}
- {{cite journal | vauthors=Tyteca S, Vandromme M, Legube G |title=Tip60 and p400 are both required for UV-induced apoptosis but play antagonistic roles in cell cycle progression. |journal=EMBO J. |volume=25 |issue= 8 |pages= 1680–9 |year= 2006 |pmid= 16601686 |doi= 10.1038/sj.emboj.7601066 | pmc=1440826 |display-authors=etal}}
{{refend}}
{{gene-12-stub}}