Eaton's reagent
{{Short description|Chemical compound}}
{{Expand German}}
{{Chembox
| verifiedrevid =
| ImageFileL1 = Phosphorus-pentoxide-3D-balls.png
|ImageFileR1=Methanesulfonic-acid-3D-balls.png
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| OtherNames = Phosphorus pentoxide-methanesulfonic acid
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{{Chembox Identifiers
| CASNo = 39394-84-8
| CASNo_Ref = {{cascite|correct|CAS}}
| EINECS = 679-375-3
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{{Chembox Properties
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| Solubility = hydrolyzes}}
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Eaton's reagent{{cite journal | doi = 10.1021/jo00987a028 |author1=Eaton, P. E. |author2=Carlson, G. R. |author3=Lee, J. T. | title = Phosphorus pentoxide-methanesulfonic acid. Convenient alternative to polyphosphoric acid | journal = J. Org. Chem. | year = 1973 | volume = 38 | issue = 23 | pages = 4071}} (10 wt% phosphorus pentoxide solution in methanesulfonic acid) is used as an alternative to polyphosphoric acid in chemical synthesis to promote acylation reactions.