Ecromeximab

{{Short description|Monoclonal antibody}}

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| type = mab

| mab_type = mab

| source = xi/o

| target = GD3 ganglioside

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| CAS_number = 292819-64-8

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| UNII = M76FX2JZRM

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| molecular_weight = 145255

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Ecromeximab is a chimeric monoclonal antibody being developed for the treatment of malignant melanoma.{{cite web | title = Statement On A Nonproprietary Name Adopted By The USAN Council - Ecromeximab | url = https://searchusan.ama-assn.org/usan/documentDownload?uri=/unstructured/binary/usan/ecromeximab.pdf | publisher = American Medical Association }}{{ClinicalTrialsGov|NCT00679289|Phase II Study of KW2871 Combined With High Dose Interferon-alpha2b in Patients With Metastatic Cutaneous Melanoma}}{{cite journal | vauthors = Tarhini AA, Moschos SJ, Lin Y, Lin HM, Sander C, Yin Y, Venhaus R, Gajewski TF, Kirkwood JM | title = Safety and efficacy of the antiganglioside GD3 antibody ecromeximab (KW2871) combined with high-dose interferon-α2b in patients with metastatic melanoma | journal = Melanoma Research | volume = 27 | issue = 4 | pages = 342–350 | date = August 2017 | pmid = 28489678 | doi = 10.1097/CMR.0000000000000353 }}

The drug was developed by Kyowa Hakko Kogyo Co., Ltd. As of December 2015 development had been discontinued.{{cite web | title = Ecromeximab | url = http://adisinsight.springer.com/drugs/800013219 | work = AdisInsight }}

References

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{{Monoclonals for tumors}}

Category:Monoclonal antibodies

Category:Abandoned drugs

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