Elazer R. Edelman

{{Short description|American engineer, scientist and cardiologist}}

{{Infobox scientist

| name = Elazer Edelman

| birth_date =

| birth_place =

| death_date =

| death_place =

| fields = Biomedical Engineering
Cardiology
Vascular Biology

| workplaces = Massachusetts Institute of Technology
Harvard Medical School
Brigham and Women's Hospital

| education = Massachusetts Institute of Technology (BS, MS, PhD)
Harvard University (MD)

| doctoral_advisor = Robert S. Langer

| academic_advisors = Morris Karnovsky

| known_for = Atherosclerotic arterial disease, vascular biology, drug delivery

| children = 3, including Alex and Adam Edelman

}}

Elazer R. Edelman is an American engineer, scientist and cardiologist. He is the Edward J. Poitras Professor in Medical Engineering and Science at the Massachusetts Institute of Technology (MIT), Professor of Medicine at Harvard Medical School and at Brigham and Women's Hospital (BWH), and a practicing cardiologist at BWH.{{cite web|title=Edelman - Institute for Medical Engineering & Science|url=http://imes.mit.edu/people/faculty/edelman-elazer/|publisher=Institute for Medical Engineering and Science at MIT|accessdate=January 12, 2016}}{{cite web|title=BWH Physician Directory|url=http://physiciandirectory.brighamandwomens.org/Details/303|publisher=Brigham and Women's Hospital|accessdate=January 12, 2016}} He is the director of the MIT Center for Clinical and Translational Research (CCTR),{{Cite web |date=2021-12-06 |title=People |url=https://cctr.mit.edu/who-we-are/people |access-date=2024-10-11 |website=Center for Clinical and Translational Research |language=en}} the Harvard-MIT Biomedical Engineering Center,{{Cite web |title=Edelman Lab – Harvard-MIT Biomedical Engineering Center |url=https://edelmanlab.mit.edu/ |access-date=2024-10-11 |language=en-US}} and was previously director of the Institute for Medical Engineering and Science (IMES) at MIT.{{Cite web |date=2024-08-09 |title=Alex Shalek named director of the Institute for Medical Engineering and Science |url=https://news.mit.edu/2024/alex-shalek-named-director-mit-institute-medical-engineering-science-0809 |access-date=2024-10-11 |website=MIT News {{!}} Massachusetts Institute of Technology |language=en}} He is also the Program Director of the MIT Graduate Education in Medical Sciences program within the Harvard-MIT Division of Health Sciences and Technology.{{cite web|title=Elazer Edelman edelmanlab|url=https://edelmanlab.mit.edu/elazer-edelman|publisher=Harvard-MIT Biomedical Engineering Center|accessdate=January 12, 2016}}{{cite web|title=HST to Offer New Medical Program|url=http://tech.mit.edu/V126/N54/54gems.html|publisher=The Tech|accessdate=January 12, 2016}}

At BWH, he serves as a senior attending physician in the coronary care unit. He is currently the Chief Scientific Advisor for the journal Science Translational Medicine.{{cite web|title=Editorial staff and scientific advisory boards|url=http://stm.sciencemag.org/content/editorial-staff-and-scientific-advisory-boards|publisher=Science|accessdate=January 12, 2016}}

Edelman was elected as a member of the National Academy of Engineering in 2012 for contributions to the design, development, and regulation of local cardiovascular drug delivery and drug eluting stents. He is also a member of the American Academy of Arts and Sciences, National Academy of Inventors and the National Academy of Medicine.{{cite web|title=Alphabetical List of Active Members|url=https://www.amacad.org/multimedia/pdfs/alphalist.pdf|publisher=American Academy of Arts and Sciences|accessdate=February 19, 2016}}{{cite web|title=Current NAI Fellows|url=http://www.academyofinventors.org/search-fellows.asp|publisher=National Academy of Inventors|accessdate=February 19, 2016}}{{cite web|title=Elazer Edelman - National Academy of Engineering Directory|url=http://www.nae.edu/MembersSection/MemberDirectory/56126.aspx|publisher=National Academy of Engineering|accessdate=January 12, 2016}}{{cite web|title=Elazer Edelman - Institute of Medicine Profile|url=http://iom.nationalacademies.org/Global/Directory/Member%20Detail.aspx?id=0020013828|publisher=National Academy of Medicine|accessdate=January 12, 2016}}{{Dead link|date=August 2019 |bot=InternetArchiveBot |fix-attempted=yes }}

Background and education

Edelman was raised in the greater Boston area. He attended the Massachusetts Institute of Technology, where he received bachelor's degrees in Electrical Engineering and Computer Science (EECS) and in Applied Biology, and a master's degree in EECS. He earned his M.D. degree with distinction from Harvard Medical School and Ph.D. in Medical Engineering and Medical Physics within the Harvard-MIT Division of Health Sciences and Technology. He conducted his Ph.D. thesis work under the direction of Robert Langer to define the mathematics of regulated and controlled drug delivery. Edelman completed his medical training at Brigham and Women's Hospital and is board certified in internal medicine and cardiology. Following this, he spent six years as a research fellow under the tutelage of Prof. Morris J. Karnovsky to work on the biology of vascular repair.{{cite web |title=Elazer Edelman - Curriculum Vitae |url=https://edelmanlab.mit.edu/sites/default/files/Elazer%20Edelman%20Curriculum%20Vitae%20%28Updated%2010-2015%29_0.pdf |publisher=Elazer Edelman |access-date=January 12, 2016 |url-status=dead |archive-url=https://web.archive.org/web/20160305173803/https://edelmanlab.mit.edu/sites/default/files/Elazer%20Edelman%20Curriculum%20Vitae%20%28Updated%2010-2015%29_0.pdf |archive-date=March 5, 2016 }} Edelman and his wife, Cheryl, have 3 children: Alex, A.J., and Austin.

Research

Edelman is a major advocate of multidisciplinary research.{{cite web|title=Elazer Edelman - How Do We Bridge the Gap in Medical Innovation?|url=http://www.tedmed.com/talks/show?id=17771|publisher=TEDMED|accessdate=February 19, 2016}}{{cite web|title=Elazer Edelman - TEDMED Q&A|url=http://www.tedmed.com/talks/show?id=17771&videoId=234004|publisher=TEDMED|accessdate=February 19, 2016}} Through his research centers, he combines teams of clinicians, engineers, and scientists from both academia and industry to create highly effective and clinically relevant solutions to medical problems.{{cite web|title=Taking many forms of expertise to heart|date=December 9, 2015 |url=https://news.mit.edu/2015/elazer-edelman-cardiovascular-health-1209|publisher=MIT News|accessdate=January 12, 2016}} Through this approach, Edelman and his students have been credited as some of the key contributors and pioneers of the coronary stent. They critically aided in the development, characterization, and optimization of the first bare-metal stents and subsequent iterations including drug-eluting stents.{{cite journal | last = Hwang| first = CW |author2=Wu D |author3=Edelman ER | year = 2001 | title = Physiological transport forces govern drug distribution for stent-based delivery | journal = Circulation | volume = 104 | pages = 600–605 |pmid=11479260 | doi = 10.1161/hc3101.092214 | issue = 5 | doi-access = free }}{{cite journal |vauthors=Hwang CW, Levin AD, Jonas M, Li PH, Edelman ER |title=Thrombosis modulates arterial drug distribution for drug-eluting stents |journal=Circulation |volume=111 |issue=13 |pages=1619–26 |year=2005 |pmid=15795325 |doi=10.1161/01.CIR.0000160363.30639.37|doi-access=free }} Edelman's research programs fall in the following general categories:

polymer-based controlled and modulated drug delivery
vascular biology, glycobiology, and growth factor biochemistry
tissue engineering
biomaterials and tissue interactions
device biology

Awards and honors

Edelman has authored or co-authored more than 680 original scientific publications, holds some 80 patents, and has trained more than 300 students and post-doctoral fellows. He has served on several advisory boards including the Science Board to the Food and Drug Administration.{{cite web |title=Elazer Edelman Bibliography |url=http://edelmanlab.mit.edu/sites/default/files/Elazer%20Edelman%20Bibliography%20%28Updated%2010-2015%29_0.pdf |publisher=Elazer Edelman |access-date=January 12, 2016 |url-status=dead |archive-url=https://web.archive.org/web/20160306025409/http://edelmanlab.mit.edu/sites/default/files/Elazer%20Edelman%20Bibliography%20%28Updated%2010-2015%29_0.pdf |archive-date=March 6, 2016 }}

Edelman has been elected a fellow of the Association of American Physicians, American College of Cardiology, American Heart Association, American Institute for Medical and Biological Engineering, American Society of Clinical Investigators, American Society of Mechanical Engineers, Association of University Cardiologists, American Academy of Arts and Sciences, National Academy of Engineering, National Academy of Medicine, and National Academy of Inventors. He received the Officer's Cross of the Spanish Order of Civil Merit in 2010.{{cite web|title=HST's Edelman receives award from Spanish government|date=June 22, 2010 |url=https://news.mit.edu/2010/hsts-edelman-receives-award-spanish-government|publisher=MIT News|accessdate=January 12, 2016}}

Selected awards received by Edelman include:

2018: Distinguished Scientist Award, American College of Cardiology{{cite web|title=2018 Distinguished Awardees|url=https://www.acc.org/membership/member-benefits-and-resources/award-programs/acc-distinguished-awards-program/2018-distinguished-awardees|publisher=ACC|accessdate=January 29, 2019}}
2017: Career Achievement Award, Transcatheter Cardiovascular Therapeutics (TCT){{cite web|title=Elazer Edelman honored with Cardiovascular Research Foundation career achievement award|date=October 13, 2017 |url=https://news.mit.edu/2017/mit-elazer-edelman-awarded-tct-career-achievement-award-1013|publisher=MIT News|accessdate=October 16, 2017}}
2016: Plenary Lecture, Royal Academy of Medicine in Ireland Bioengineering Section{{cite web|title=Bioengineering in Ireland 22|url=http://bini2016.ie/|publisher=Royal Academy of Medicine in Ireland|access-date=February 19, 2016|archive-url=https://web.archive.org/web/20160301131608/http://bini2016.ie/|archive-date=March 1, 2016|url-status=dead}}
2015: Flexner Discovery Lecturer, Vanderbilt University Medical Center{{cite web|title=Discovery Lecture Series - 2015 Speakers|url=http://www.mc.vanderbilt.edu/root/vumc.php?site=dls&doc=46393|publisher=Vanderbilt University Medical Center|accessdate=February 19, 2016}}
2015: Massimo Calabresi Lecturer, Yale University
2015: Dean's Distinguished Lecture, Weill Cornell Medical School{{cite web|title=Dean's Distinguished Lecture Series|url=http://weill.cornell.edu/about-us/dean/events.html|publisher=Weill Cornell Medical College|accessdate=February 19, 2016}}
2014: Lifetime Achievement Award, International Conference on Innovation{{cite web|title=Awards, Honors, & Grants|url=http://www.brighamandwomens.org/About_BWH/publicaffairs/news/awards/Award_Honor.aspx?sub=0&PageID=1967|publisher=Brigham and Women's Hospital|accessdate=January 12, 2016}}
2014: Clemson Award for Basic Research, The Society for Biomaterials{{cite web|title=Past Awardees|url=http://biomaterials.org/awards/past-awardees#2014%20Awardees|publisher=Society for Biomaterials|accessdate=January 12, 2016}}
2012: Hollingsworth Distinguished Lecturer, University of Texas at Austin Department of Biomedical Engineering, Cockrell School
2011: Lewis Katz Visiting Professorship in Cardiovascular Research, Columbia University{{cite web|title=Awards, Honors, & Grants|url=http://www.brighamandwomens.org/About_BWH/publicaffairs/news/awards/Award_Honor.aspx?sub=0&PageID=1000|publisher=Brigham and Women's Hospital|accessdate=February 19, 2016}}
2010: Officer's Cross of the Spanish Order of Civil Merit
2009: Jeffrey M. Hoeg Arteriosclerosis, Thrombosis and Vascular Biology Award for Basic Science and Clinical Research{{cite web|title=Jeffrey M. Hoeg Award for Basic Science & Clinical Research |url=http://my.americanheart.org/professional/Councils/AwardsandLectures/CareerAchievement/Jeffrey-M-Hoeg-Award-for-Basic-Science-Clinical-Research_UCM_322545_Article.jsp |publisher=American Heart Association |access-date=January 12, 2016 |url-status=dead |archive-url=https://web.archive.org/web/20150915160147/http://my.americanheart.org/professional/Councils/AwardsandLectures/CareerAchievement/Jeffrey-M-Hoeg-Award-for-Basic-Science-Clinical-Research_UCM_322545_Article.jsp |archive-date=September 15, 2015 }}
2007: A. Clifford Barger Excellence in Mentoring Award{{cite web|title=Excellence in Mentoring Awards Past Recipients|url=https://mfdp.med.harvard.edu/awards/excellence-mentoring-award/past-recipients|publisher=HMS|accessdate=January 12, 2016}}
2006: American Society for Testing and Materials (ASTM) Joseph S. Barr Award{{cite web|title=Awards and Recipients Database|url=http://www.astm.org/MEMBERSHIP/all_awards_sp.html|publisher=ASTM|accessdate=January 12, 2016}}
1992: Marcus Award, American Heart Association
1982: Soma Weiss Award, Harvard Medical School

Personal life

Edelman is married to Cheryl, a real estate lawyer,{{Cite web |last=vCard |title=Cheryl Edelman {{!}} DLA Piper |url=https://www.dlapiper.com/en-us/people/e/cheryl-edelman |access-date=2024-07-13 |website=www.dlapiper.com |language=en-US}} and lives in Brookline, Massachusetts. He has three sons, Austin, Israeli Olympian Adam Edelman, and comedian Alex Edelman.

References

External links

[http://edelmanlab.mit.edu Edelman Lab]
[http://phdtree.org/scholar/edelman-elazer-r/ Academic Family Tree of Professor Elazer Edelman]
[http://www.tedmed.com/speakers/show?id=17770 TedMed Talk by Elazer Edelman]

Category:People from Boston

Category:MIT School of Engineering faculty

Category:MIT School of Engineering alumni

Category:Harvard Medical School alumni

Category:Engineers from Massachusetts

Category:American cardiologists

Category:Year of birth missing (living people)

Category:Living people

Category:Fellows of the American Institute for Medical and Biological Engineering

Category:Fellows of the American College of Cardiology

Category:Members of the National Academy of Medicine