Eleanor Stride
{{short description|Professor of Biomaterials}}
{{Use dmy dates|date=April 2022}}
{{Infobox scientist
| name = Eleanor Stride
| workplaces = University College London
| alma_mater = University College London
| doctoral_advisor = Nader Saffari
| awards = Institution of Engineering and Technology Harvey Prize (2015)
Philip Leverhulme Prize (2009)
}}
Eleanor Phoebe Jane Stride {{Post-nominals|country=GBR|size=100%|OBE|FREng|}} is a Professor of Biomaterials at St Catherine's College, Oxford. Stride engineers drug delivery systems using carefully designed microbubbles and studies how they can be used in diagnostics.
Education
Stride completed her Bachelor's degree in Mechanical Engineering and a PhD in the Ultrasonics group at University College London.{{Cite web|url=http://www.ibme.ox.ac.uk/research/non-invasive-therapy-drug-delivery/people/dr-eleanor-stride|title=Professor Eleanor Stride — Institute of Biomedical Engineering|website=www.ibme.ox.ac.uk|language=en|access-date=2018-07-03}}{{Citation|last=UCL|title=Mini-lecture: The science of microbubbles (UCL)|date=2010-03-15|url=https://www.youtube.com/watch?v=gz9nAw3sDa4|access-date=2018-07-03}} She had planned to work for Aston Martin.{{Citation|last=HAVAS LYNX|title=Episode 5: #LXAcademy Launch 2018, Professor Eleanor Stride - A Completely New Angle|date=2018-06-20|url=https://www.youtube.com/watch?v=eMTkN3aysF0|access-date=2018-07-03}} Whilst there became interested in using ultrasound for imaging microbubbles, and was awarded a Royal Society Brian Mercer Innovation Feasibility Award.{{Cite journal|title=Investigating the significance of multiple scattering in ultrasound contrast agent particle populations - IEEE Journals & Magazine|language=en-US|doi=10.1109/TUFFC.2005.1563278|pmid=16463501|year=2005|last1=Stride|first1=E.|last2=Saffari|first2=N.|journal=IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control|volume=52|issue=12|pages=2332–45|s2cid=26846678|url=https://discovery.ucl.ac.uk/id/eprint/11711/1/11711.pdf}}{{Cite web|url=https://medium.com/oxford-university/international-day-of-women-and-girls-in-science-d7b2bf1810d1|title=International Day of Women and Girls in Science|date=2018-02-09|website=Oxford University|access-date=2018-07-03}}
Research and career
Stride was awarded a Royal Academy of Engineering lectureship at University College London, where she explored ultrasound for drug delivery.{{Cite news|url=https://eandt.theiet.org/content/articles/2015/02/interview-eleanor-stride-iet-a-f-harvey-prize-winner/|title=Interview: Eleanor Stride IET A F Harvey prize winner|date=2015-02-03|access-date=2018-07-03|language=en-US}} Microbubbles in the bloodstream created a strong ultrasound echo, which allows doctors to trace where the blood is flowing.{{Cite web|url=https://www.universityvideos.org/Document?db=VIDEODIGITALLIBRARY&query=(select%20124427)|title=Top Universities {{!}} Video Search Site|website=www.universityvideos.org|language=en|access-date=2018-07-03}} Whilst at University College London she collaborated with the Wellcome Collection.{{Cite news|url=https://wellcomecollection.org/articles/eating-walking-stretching-and-bubbles/|title=Eating, walking, stretching and bubbles|work=Wellcome Collection|access-date=2018-07-03|language=en}} She was awarded an Engineering and Physical Sciences Research Council Challenging Engineering Award in 2011.{{Cite web|url=https://epsrc.ukri.org/research/ourportfolio/themes/engineering/activities/chaleng/cureng/dreleanorstride/|title=Dr Eleanor Stride, University College London - EPSRC website|website=epsrc.ukri.org|language=en|access-date=2018-07-03}} That year she joined the Oxford Institute of Biomedical Engineering in 2011.{{Cite web|url=https://www.oxfordsparks.ox.ac.uk/content/eleanor-stride|title=Eleanor Stride {{!}} www.oxfordsparks.ox.ac.uk|website=www.oxfordsparks.ox.ac.uk|language=en|access-date=2018-07-03}} She is a Fellow at St Catherine's College, Oxford.{{Cite web|url=https://events.theiet.org/kelvin/speaker.cfm|title=Why haven't we cured cancer? - IET Events|website=events.theiet.org|language=en-US|access-date=2018-07-03}} The award allowed her to develop new agents for targeted drug delivery, which allowed clinicians more control in transporting and releasing medical therapeutics. Stride encapsulates deactivated drugs in 'carriers' which can be navigated around the body to a target. She also explored how her novel agents interacted with cells and tissue. Her research could be used to deliver chemotherapy.{{Cite news|url=https://www.erafoundation.org/outreach/born-engineer-dr-eleanor-stride/|title=Dr Eleanor Stride — ERA Foundation|date=2014-11-26|work=ERA Foundation|access-date=2018-07-03|language=en-US}} She has several patents for the creation and imaging of microbubbles.{{Citation |title= Method and apparatus for generating bubbles |url= https://patents.google.com/patent/WO2017125753A1/en |id= issue-date: 2017-01-20 |access-date= 2018-07-03}}{{Citation |title= Beverage composition comprising nanoencapsulated oxygen |url= https://patents.google.com/patent/EP3324929A1/en |id= issue-date: 2016 |access-date= 2018-07-03}} She created the spin-out company AtoCap.{{Cite web |url= http://atocap.com/team |title=Meet The Team - Atocap |website= Meet The Team - Atocap |language=en-GB |access-date= 2018-07-03}}{{Cite web |url= https://www.ndorms.ox.ac.uk/team/eleanor-stride |title= Eleanor Stride — Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences |website= www.ndorms.ox.ac.uk |language=en |access-date= 2018-07-03 }} AtoCap focussed on the treatment of chronic infections.{{Cite journal |last1= Labbaf |first1= Sheyda |last2=Horsley |first2=Harry |last3=Chang |first3=Ming-Wei |last4=Stride |first4=Eleanor |last5=Malone-Lee |first5= James |last6=Edirisinghe |first6=Mohan |last7= Rohn |first7=Jennifer L. |date= 2013-12-06 |title= An encapsulated drug delivery system for recalcitrant urinary tract infection |journal= Journal of the Royal Society Interface |language=en |volume=10 |issue=89 |pages= 20130747 |doi= 10.1098/rsif.2013.0747 |issn= 1742-5689 |pmid= 24068180|pmc=3808553 }}
Stride was appointed full Professor in 2014. By using custom-designed magnetic arrays, the Stride group have managed to trap particles in tissue several centimetres deep.{{Cite journal |last1= Barnsley |first1=Lester C. |last2=Carugo |first2= Dario |last3=Owen |first3=Joshua |last4=Stride |first4= Eleanor |date= 2015-11-07 |title= Halbach arrays consisting of cubic elements optimised for high field gradients in magnetic drug targeting applications |journal= Physics in Medicine and Biology |volume=60 |issue=21 |pages= 8303–8327 |doi= 10.1088/0031-9155/60/21/8303 |issn= 1361-6560|pmid=26458056|bibcode=2015PMB....60.8303B |s2cid=29807333 }} She demonstrated that it is possible to load oxygen into microbubbles to improve Sonodynamic therapy.{{Cite journal |last1=McEwan |first1=Conor |last2=Owen |first2= Joshua |last3= Stride |first3=Eleanor |last4=Fowley |first4=Colin |last5=Nesbitt |first5=Heather |last6=Cochrane |first6=David |last7=Coussios |first7=Constantin C. |last8=Borden |first8=M. |last9= Nomikou |first9=Nikolitsa |date= 2015-04-10 |title= Oxygen carrying microbubbles for enhanced sonodynamic therapy of hypoxic tumours |journal=Journal of Controlled Release |volume=203 |pages=51–56 |doi= 10.1016/j.jconrel.2015.02.004 |issn= 1873-4995 |pmid= 25660073}}{{Cite journal |last1=McEwan|first1=Conor|last2=Kamila|first2=Sukanta|last3=Owen|first3=Joshua|last4=Nesbitt|first4=Heather|last5=Callan|first5=Bridgeen|last6=Borden|first6=Mark|last7=Nomikou|first7=Nikolitsa|last8=Hamoudi|first8=Rifat A. |last9= Taylor |first9=Mark A. |date= February 2016 |title= Combined sonodynamic and antimetabolite therapy for the improved treatment of pancreatic cancer using oxygen loaded microbubbles as a delivery vehicle |journal= Biomaterials |volume=80 |pages=20–32 |doi= 10.1016/j.biomaterials.2015.11.033 |issn= 1878-5905 |pmid= 26702983}} She was made a Fellow of the Royal Academy of Engineering in 2017.{{Cite web |title=Professor Eleanor Stride FREng |url=https://raeng.org.uk/about-us/fellowship/new-fellows-2017/eleanor-stride |access-date=2025-02-27 |website=Royal Academy of Engineering}}
= Public engagement and diversity =
In 2016 Stride was named one of the Top 50 Influential Women in Engineering.{{Cite web|url=http://www.ibme.ox.ac.uk/research/non-invasive-therapy-drug-delivery/bubbl-news/professor-eleanor-stride-makes-top-50-women-in-engineering-list|title=June 2016 - Professor Eleanor Stride makes top 50 Women in Engineering List — Institute of Biomedical Engineering|website=www.ibme.ox.ac.uk|language=en|access-date=2018-07-03}}{{Cite web|url=http://www.stcatz.ox.ac.uk/Eleanor-Stride-top50engineer|title=Professor Eleanor Stride named as one of the top 50 women in Engineering {{!}} www.stcatz.ox.ac.uk|website=www.stcatz.ox.ac.uk|language=en|access-date=2018-07-03}} She has appeared on BBC Radio 4.{{Cite web|url=https://www.bbc.co.uk/programmes/p019glwd|title=Nano-bubbles and drug delivery, The Imagineers - BBC Two|website=BBC|language=en-GB|access-date=2018-07-03}}{{Cite web|url=http://www.bbc.co.uk/programmes/articles/FbMNhVN6GPrXCjjPMLL54d/five-things-we-learnt-about-women-in-engineering-from-professor-dame-ann-dowling|title=Woman's Hour - Five things we learnt about women in engineering from Professor Dame Ann Dowling - BBC Radio 4|website=BBC|language=en-GB|access-date=2018-07-03}} She features on a number of YouTube videos with the Royal Institution.{{Citation|last=The Royal Institution|title=Born to Engineer - Biomedical bubbles with Eleanor Stride|date=2014-04-15|url=https://www.youtube.com/watch?v=JPIqS-A5CQM|access-date=2018-07-03}} She created a revision series with BBC bitesize.{{Cite web|url=https://www.bbc.com/education/clips/z46w6sg|title=BBC Bitesize - Higher Engineering science - Nano-bubbles and drug delivery|website=BBC Bitesize|access-date=2018-07-03}}
= Awards =
- {{Timeline-event|date={{Start date|2009}}|event= Philip Leverhulme Prize}}{{Cite web|url=http://www.ucl.ac.uk/news/news-articles/1003/10031701|title=The promise of microbubbles|website=www.ucl.ac.uk|date=16 March 2010|language=en|access-date=2018-07-03}}
- {{Timeline-event|date={{Start date|2009}}|event= EPSRC & Journal of the Royal Society Interface Award (recognition of best paper 2004 - 2009)}}
- {{Timeline-event|date={{Start date|2009}}|event= SET for Britain Engineering medal}}
- {{Timeline-event|date={{Start date|2010}}|event= Worshipful Company of Armourers and Brasiers Venture Prize}}
- {{Timeline-event|date={{Start date|2013}}|event= Acoustical Society of America Lindsay Award}}{{Cite news|url=https://acousticalsociety.org/acoustical-society-of-america-awards/|title=Acoustical Society of America Awards - Acoustical Society of America|work=Acoustical Society of America|access-date=2018-07-03|language=en-US}}{{Cite web|url=http://www.eng.ox.ac.uk/about/news/dr-eleanor-stride-receives-2013-r.-bruce-lindsay-award-of-the-acoustical-society-of-america|title=Dr Eleanor Stride receives 2013 R. Bruce Lindsay Award of the Acoustical Society of America — Department of Engineering Science|website=www.eng.ox.ac.uk|language=en|access-date=2018-07-03}}
- {{Timeline-event|date={{Start date|2015}}|event= Institution of Engineering and Technology Harvey Prize}}{{Citation|last=IET|title=Professor Eleanor Stride: 2014 IET A.F. Harvey Prize Winner|date=2015-02-25|url=https://www.youtube.com/watch?v=XRAMQhbzceU|access-date=2018-07-03}}
- {{Timeline-event|date={{Start date|2017}}|event= Fellow of the Royal Academy of Engineering}}
Stride was appointed Officer of the Order of the British Empire (OBE) in the 2021 New Year Honours for services to engineering.{{London Gazette|issue=63218|supp=y|page=N14|date=31 December 2020}}
References
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Category:Fellows of the Royal Academy of Engineering
Category:Female fellows of the Royal Academy of Engineering
Category:British women engineers
Category:Alumni of University College London
Category:Fellows of St Catherine's College, Oxford
Category:21st-century women engineers