Enilospirone

{{Short description|Chemical compound}}

{{Drugbox

| IUPAC_name = 6-(3-chlorophenoxy)-2-methyl-1-oxa-4-azaspiro[4.5]decan-3-one

| image = Enilospirone.png

| width = 120

| tradename =

| pregnancy_category =

| legal_status = Uncontrolled

| routes_of_administration = Oral

| bioavailability =

| metabolism =

| elimination_half-life =

| excretion =

| CAS_number = 59798-73-1

| ATC_prefix = none

| ATC_suffix =

| PubChem = 68794

| ChemSpiderID = 62034

| UNII_Ref = {{fdacite|correct|FDA}}

| UNII = WO31V62797

| C=15 | H=18 | Cl=1 | N=1 | O=3

}}

Enilospirone (CERM-3,726) is a selective 5-HT1A receptor agonist of the azapirone class.{{cite journal | vauthors = Maurel JL, Autin JM, Funes P, Newman-Tancredi A, Colpaert F, Vacher B | title = High-efficacy 5-HT1A agonists for antidepressant treatment: a renewed opportunity | journal = Journal of Medicinal Chemistry | volume = 50 | issue = 20 | pages = 5024–33 |date=October 2007 | pmid = 17803293 | doi = 10.1021/jm070714l }}

See also

References

{{Reflist}}

Further reading

  • {{cite journal | vauthors = Nicholson AN, Stone BM | title = 6-(3-chloro)-phenoxy-2-methyl-1-oxa-4-azospiro-[4,5]decane-3-one (CERM 3726) and sleep of healthy men | journal = Psychopharmacology | volume = 76 | issue = 2 | pages = 157–9 | year = 1982 | pmid = 6805026 | doi = 10.1007/BF00435270| s2cid = 666391 }}

{{Anxiolytics}}

{{Antidepressants}}

{{Serotonergics}}

{{Piperazines}}

Category:3-Chlorophenyl compounds

Category:Phenol ethers

Category:Lactams

Category:Azapirones

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