Erminio Costa
{{Infobox scientist
| name = Erminio Costa
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| birth_date =March 9, 1924
| birth_place = Cagliari, Sardinia, Kingdom of Italy
| death_date = {{dda|2009|11|28|1924|3|24}}Social Security Death Index, 1935-2014. Social Security Administration.
| death_place = Chevy Chase, Maryland, U.S.
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| citizenship = American
| nationality = Italian
| fields = Neuropharmacology
| workplaces = Columbia University, Georgetown University
| alma_mater = University of Cagliari
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| known_for = Research on serotonin, the GABA receptor, and metabotropic glutamate receptors
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| spouse = Ingeborg Hanbauer
| children = Michael, Max and Robert (Robert died in 2006){{Cite journal | last1 = Grayson | first1 = D. R. | last2 = Guidotti | first2 = A. | doi = 10.1038/npp.2009.231 | title = Erminio Costa | journal = Neuropsychopharmacology | volume = 35 | issue = 13 | pages = 2646 | year = 2010 | pmc = 3055564}}
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Erminio "Mimo" Costa (March 9, 1924 – November 28, 2009) was an Italian-American neuroscientist.{{cite book |author1=Clayton, Paula J. |author1-link=Paula Clayton|author2=Fatemi, S. Hossein |title=The medical basis of psychiatry |publisher=Humana Press |location=Totowa, NJ |year=2008 |isbn=1-58829-917-1 }} His research interests covered brain serotonergic activity in health and disease, benzodiazepine-GABA interactions,{{cite book |author=Barondes, Samuel H. |title=Better than Prozac: Creating the next generation of psychiatric drugs |publisher=Oxford University Press |location=Oxford [Oxfordshire] |year=2003 |isbn=0-19-515130-5 |url-access=registration |url=https://archive.org/details/betterthanprozac00baro }} benzodiazepine action at GABAA receptors, neurophysiological role of neurosteroids,{{Cite journal|title = Brain allopregnanolone regulates the potency of the GABA(A) receptor agonist muscimol|journal = Neuropharmacology|date = 2000-01-28|issn = 0028-3908|pmid = 10698010|pages = 440–448|volume = 39|issue = 3|first = G.|last = Pinna|first2 = V.|last2 = Uzunova|first3 = K.|last3 = Matsumoto|first4 = G.|last4 = Puia|first5 = J. M.|last5 = Mienville|first6 = E.|last6 = Costa|first7 = A.|last7 = Guidotti|doi=10.1016/s0028-3908(99)00149-5|hdl = 11380/1248311|hdl-access = free}} and GABAergic dysfunction and changes in the expression of reelin and GAD67 in schizophrenia.{{cite journal |vauthors=Costa E, Chen Y, Davis J, Dong E, Noh JS, Tremolizzo L, Veldic M, Grayson DR, Guidotti A |title=REELIN and schizophrenia: a disease at the interface of the genome and the epigenome |journal=Mol. Interv. |volume=2 |issue=1 |pages=47–57 |date=February 2002 |pmid=14993361 |doi=10.1124/mi.2.1.47 |url=http://molinterv.aspetjournals.org/cgi/pmidlookup?view=long&pmid=14993361 |archive-url=https://archive.today/20130414065310/http://molinterv.aspetjournals.org/cgi/pmidlookup?view=long&pmid=14993361 |url-status=dead |archive-date=2013-04-14 |url-access=subscription }} He published more than 1,000 articles.{{cite web | url=http://www.psych.uic.edu/news/costa.htm | title=UIC, Dept. of Psychiatry News: Erminio Costa, M.D., Logs 1,000th Publication | archive-url=https://web.archive.org/web/20040430172358/http://www.psych.uic.edu/news/Costa.htm | archive-date=30 April 2004}} The June 2011 issue of the journal Neuropharmacology was dedicated to him.{{cite journal |author=Bloom FE |title=Mentored and inspired by Mimo: a tribute to Erminio Costa |journal=Neuropharmacology |volume=60 |issue=7-8 |pages=1003–6 |date=June 2011 |pmid=20869374 |doi=10.1016/j.neuropharm.2010.09.019 |doi-access=free }}
Career
- July 1947 - M.D. 110/110 cum laude, University of Cagliari, Italy
- 1950-1960 - Thudichum Psychiatric Research Laboratory, Galesburg Research Hospital, Galesburg, Illinois
- 1960-1965 - Deputy Chief, Laboratory of Chemical Pharmacology at NHLI - NIH, Bethesda, Maryland
- 1965-1968 - Associate Professor of Pharmacology and Neurology, College of Physicians and Surgeons of Columbia University, New York, NY
- 1968-1985 - Chief of the Laboratory of Preclinical Pharmacology, NIMH, St. Elizabeths Hospital, Washington, DC
- 1985-1994 - Director and Founder, Institute of Neuroscience, and Professor of Pharmacology, Georgetown University, Washington, DC
- 1994-1995 - Director, Center for Neuropharmacology, Nathan Kline Institute for Psychiatric Research, New York University, New York, NY
- 1995 - Scientific Director, Psychiatric Institute, Professor of Biochemistry in Psychiatry, Department of Psychiatry, College of Medicine, University of Illinois at Chicago, Chicago, Illinois
- 1982 - Member, National Academy of Sciences
- 1991 - Member of "Accademia dei Lincei" founded by Galileo Galilei in 1602, Rome
Books
- Advances in Biochemical Psychopharmacology (1969)
- Biochemistry and Pharmacology of the Basal Ganglia (1966)
- Biochemistry of Simple Neuronal Models (1970)
- Neurosteroids and Brain Function (1991)
- The Endorphins - Vol. 18 (1985)
See also
- Bernard Brodie, in whose laboratory Costa worked for a time.
References
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External links
- [https://web.archive.org/web/20090414201714/http://www.psych.uic.edu/faculty/costa.htm Erminio Costa, M.D.]
- [https://web.archive.org/web/20100116124905/http://www.schizophreniaforum.org/new/detail.asp?id=1559 Obituary—Erminio Costa, M.D. (1924-2009), University of Illinois at Chicago] - obituary at Schizophrenia Research Forum
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Category:Italian neuroscientists
Category:Members of the United States National Academy of Sciences
Category:University of Cagliari alumni