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Expressome

Expressome may refer to:

  • A supramolecular complex consisting of RNA polymerase and a trailing ribosome linked by a shared mRNA. The expressome complex mediates a mechanism of gene expression regulation termed transcription-translation coupling.
  • The whole set of gene expression in a cell, tissue, organ, organisms, and species. Expressome is a slightly larger concept than transcriptome. The transcriptome is the set of transcripts, while expressome includes transcripts, proteins and other ligands (abundance or concentration).

See also

External links

  • [https://web.archive.org/web/20081122145613/http://bioinformatics.oupjournals.org// Bioinformatics Journal]

Category:Gene expression

References

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{{cite journal |author1=Kohler, R. |author2=Mooney, R. A. |author3=Mills, D. J. |author4=Landick, R. |author5=Cramer, P. |name-list-style=amp |year=2017 |title=Architecture of a transcribing-translating expressome. |journal=Science |volume=356 |issue=6334 |pages=194–197 |doi = 10.1126/science.aal3059 |pmid=28408604 |pmc=5528865 |bibcode=2017Sci...356..194K }}

{{cite journal |author1=Webster, M. W. |author2=Takacs, M. |author3=Zhu, C.|author4=Vidmar, V. |author5=Eduljee, A. |author6=Abdelkareem, M. |author7=Weixlbaumer, A. |name-list-style=amp |year=2020 |title=Structural basis of transcription-translation coupling and collision in bacteria. |journal=Science |volume=369 |issue=6509 |pages=1355–1359 |doi = 10.1126/science.abb5036 |pmid=32820062 |bibcode=2020Sci...369.1355W |s2cid=221222557 |doi-access=free }}

{{cite journal |author1=O'Reilly, F. J. |author2=Xue, L. |author3=Graziadei, A.|author4=Sinn, L. |author5=Lenz, S. |author6=Tegunov, D. |author7=Blötz, C. |author8=Singh, N. |author9=Hagen, W. |author10=Cramer, P. |author11=Stülke, J. |author12=Mahamid, J. |author13=Rappsilber, J. |author13-link=Juri Rappsilber |name-list-style=amp |year=2020 |title=In-cell architecture of an actively transcribing-translating expressome. |journal=Science |volume=369 |issue=6503 |pages=554–557 |doi = 10.1126/science.abb3758 |pmid=32732422 |pmc=7115962 |bibcode=2020Sci...369..554O |hdl=21.11116/0000-0006-D30E-D |hdl-access=free }}

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