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FARP2

{{Short description|Protein-coding gene in the species Homo sapiens}}

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{{Infobox_gene}}FERM, RhoGEF and pleckstrin domain-containing protein 2 is a protein that in humans is encoded by the FARP2 gene.{{cite journal | vauthors = Nagase T, Ishikawa K, Suyama M, Kikuno R, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O | title = Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro | journal = DNA Research | volume = 5 | issue = 5 | pages = 277–86 | date = Oct 1998 | pmid = 9872452 | doi = 10.1093/dnares/5.5.277 | doi-access = free }}{{cite journal | vauthors = Kubo T, Yamashita T, Yamaguchi A, Sumimoto H, Hosokawa K, Tohyama M | title = A novel FERM domain including guanine nucleotide exchange factor is involved in Rac signaling and regulates neurite remodeling | journal = The Journal of Neuroscience | volume = 22 | issue = 19 | pages = 8504–13 | date = Oct 2002 | pmid = 12351724 | pmc = 6757789| doi = 10.1523/JNEUROSCI.22-19-08504.2002}}{{cite web | title = Entrez Gene: FARP2 FERM, RhoGEF and pleckstrin domain protein 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9855}}

Interactions

FARP2 has been shown to interact with PDZK1.{{cite journal | vauthors = Gisler SM, Pribanic S, Bacic D, Forrer P, Gantenbein A, Sabourin LA, Tsuji A, Zhao ZS, Manser E, Biber J, Murer H | title = PDZK1: I. a major scaffolder in brush borders of proximal tubular cells | journal = Kidney International | volume = 64 | issue = 5 | pages = 1733–45 | date = Nov 2003 | pmid = 14531806 | doi = 10.1046/j.1523-1755.2003.00266.x | doi-access = free }}

See also

References

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Further reading

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  • {{cite journal | vauthors = Jin J, Smith FD, Stark C, Wells CD, Fawcett JP, Kulkarni S, Metalnikov P, O'Donnell P, Taylor P, Taylor L, Zougman A, Woodgett JR, Langeberg LK, Scott JD, Pawson T | title = Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization | journal = Current Biology | volume = 14 | issue = 16 | pages = 1436–50 | date = Aug 2004 | pmid = 15324660 | doi = 10.1016/j.cub.2004.07.051 | s2cid = 2371325 | doi-access = free | bibcode = 2004CBio...14.1436J }}
  • {{cite journal | vauthors = Gisler SM, Pribanic S, Bacic D, Forrer P, Gantenbein A, Sabourin LA, Tsuji A, Zhao ZS, Manser E, Biber J, Murer H | title = PDZK1: I. a major scaffolder in brush borders of proximal tubular cells | journal = Kidney International | volume = 64 | issue = 5 | pages = 1733–45 | date = Nov 2003 | pmid = 14531806 | doi = 10.1046/j.1523-1755.2003.00266.x | doi-access = free }}
  • {{cite journal | vauthors = Miyamoto Y, Yamauchi J, Itoh H | title = Src kinase regulates the activation of a novel FGD-1-related Cdc42 guanine nucleotide exchange factor in the signaling pathway from the endothelin A receptor to JNK | journal = The Journal of Biological Chemistry | volume = 278 | issue = 32 | pages = 29890–900 | date = Aug 2003 | pmid = 12771149 | doi = 10.1074/jbc.M301559200 | doi-access = free }}
  • {{cite journal | title = Toward a complete human genome sequence | journal = Genome Research | volume = 8 | issue = 11 | pages = 1097–108 | date = Nov 1998 | pmid = 9847074 | doi = 10.1101/gr.8.11.1097 | last1 = Sanger Centre | first1 = The | last2 = Washington University Genome Sequencing Cente | first2 = The | doi-access = free }}

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External links

  • {{PDBe-KB2|Q91VS8|FERM, ARHGEF and pleckstrin domain-containing protein 2}}

Category:Genes mutated in mice

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