FBP1

Fructose-1,6-bisphosphatase 1, a gluconeogenesis regulatory enzyme, catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis.

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• {{cite journal | vauthors = Yáñez AJ, Bertinat R, Spichiger C, Carcamo JG, de Los Angeles García M, Concha II, Nualart F, Slebe JC | title = Novel expression of liver FBPase in Langerhans islets of human and rat pancreas | journal = Journal of Cellular Physiology | volume = 205 | issue = 1 | pages = 19–24 | date = Oct 2005 | pmid = 15965961 | doi = 10.1002/jcp.20407 | hdl = 10533/176131 | s2cid = 40822845 | hdl-access = free }}
• {{cite journal | vauthors = Faiyaz-Ul-Haque M, Al-Owain M, Al-Dayel F, Al-Hassnan Z, Al-Zaidan H, Rahbeeni Z, Al-Sayed M, Balobaid A, Cluntun A, Toulimat M, Abalkhail H, Peltekova I, Zaidi SH | title = Novel FBP1 gene mutations in Arab patients with fructose-1,6-bisphosphatase deficiency | journal = European Journal of Pediatrics | volume = 168 | issue = 12 | pages = 1467–71 | date = Dec 2009 | pmid = 19259699 | doi = 10.1007/s00431-009-0953-9 | s2cid = 23777808 }}
• {{cite journal | vauthors = Kikawa Y, Inuzuka M, Takano T, Shigematsu Y, Nakai A, Yamamoto Y, Jin BY, Koga J, Taketo A, Sudo M | title = cDNA sequences encoding human fructose 1,6-bisphosphatase from monocytes, liver and kidney: application of monocytes to molecular analysis of human fructose 1,6-bisphosphatase deficiency | journal = Biochemical and Biophysical Research Communications | volume = 199 | issue = 2 | pages = 687–93 | date = Mar 1994 | pmid = 8135811 | doi = 10.1006/bbrc.1994.1283 }}
• {{cite journal | vauthors = Besançon F, Just J, Bourgeade MF, Van Weyenbergh J, Solomon D, Guillozo H, Wietzerbin J, Cayre YE | title = HIV-1 p17 and IFN-gamma both induce fructose 1,6-bisphosphatase | journal = Journal of Interferon & Cytokine Research | volume = 17 | issue = 8 | pages = 461–7 | date = Aug 1997 | pmid = 9282826 | doi = 10.1089/jir.1997.17.461 }}
• {{cite journal | vauthors = Gizak A, Maciaszczyk-Dziubinska E, Jurowicz M, Rakus D | title = Muscle FBPase is targeted to nucleus by its 203KKKGK207 sequence | journal = Proteins | volume = 77 | issue = 2 | pages = 262–7 | date = Nov 2009 | pmid = 19626708 | doi = 10.1002/prot.22506 | s2cid = 22934928 }}
• {{cite journal | vauthors = Zhang Y, Liang JY, Huang S, Ke H, Lipscomb WN | title = Crystallographic studies of the catalytic mechanism of the neutral form of fructose-1,6-bisphosphatase | journal = Biochemistry | volume = 32 | issue = 7 | pages = 1844–57 | date = Feb 1993 | pmid = 8382525 | doi = 10.1021/bi00058a019 }}
• {{cite journal | vauthors = Visinoni S, Khalid NF, Joannides CN, Shulkes A, Yim M, Whitehead J, Tiganis T, Lamont BJ, Favaloro JM, Proietto J, Andrikopoulos S, Fam BC | title = The role of liver fructose-1,6-bisphosphatase in regulating appetite and adiposity | journal = Diabetes | volume = 61 | issue = 5 | pages = 1122–32 | date = May 2012 | pmid = 22517657 | pmc = 3331739 | doi = 10.2337/db11-1511 }}
• {{cite journal | vauthors = Liu X, Wang X, Zhang J, Lam EK, Shin VY, Cheng AS, Yu J, Chan FK, Sung JJ, Jin HC | title = Warburg effect revisited: an epigenetic link between glycolysis and gastric carcinogenesis | journal = Oncogene | volume = 29 | issue = 3 | pages = 442–50 | date = Jan 2010 | pmid = 19881551 | doi = 10.1038/onc.2009.332 | doi-access = }}
• {{cite journal | vauthors = Kikawa Y, Inuzuka M, Jin BY, Kaji S, Koga J, Yamamoto Y, Fujisawa K, Hata I, Nakai A, Shigematsu Y, Mizunuma H, Taketo A, Mayumi M, Sudo M | title = Identification of genetic mutations in Japanese patients with fructose-1,6-bisphosphatase deficiency | journal = American Journal of Human Genetics | volume = 61 | issue = 4 | pages = 852–61 | date = Oct 1997 | pmid = 9382095 | pmc = 1715983 | doi = 10.1086/514875 }}

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Category:Human proteins