FGED Society

{{short description|Bioinformatics association}}

{{Infobox organization

|name = FGED Society

|image = mged_logo.png

|image_border =

|size = 100px

|caption =

|map =

|msize =

|mcaption =

|abbreviation = FGED

|motto =

|formation = {{start date and age|1999|11}}

|dissolved = {{end date and age|2021|09}}

|type = NPO

|status =

|purpose = Scientific

|headquarters =

|location =

|region_served =

|membership =

|language = English

|leader_title = President

|leader_name = Francis Ouellette

|main_organ = Board of directors

|parent_organization =

|affiliations =

|num_staff =

|num_volunteers =

|budget =

|website = [https://www.fged.org www.fged.org]

|remarks =

}}

The Functional GEnomics Data Society (FGED) (formerly known as the MGED Society)

was a non-profit, volunteer-run international organization

of biologists, computer scientists, and data analysts that aims to

facilitate biological and biomedical discovery through data

integration. The approach of FGED was to promote the sharing of basic research

data generated primarily via high-throughput technologies

that generate large data sets within the domain of functional genomics.

Members of the FGED Society worked with other organizations to support the effective sharing and reproducibility

of functional genomics data; facilitate the creation of

standards and software tools that leverage the standards; and promote the sharing of high quality, well

annotated data within the life sciences and biomedical communities.

Founded in 1999 as the "Microarray Gene Expression Data (MGED) Society", this organization changed its name to the "Functional Genomics Data Society" in 2010 to reflect the fact that it has broadened its focus beyond the application of DNA microarrays for gene expression analysis to include technologies such as high-throughput sequencing.{{Citation needed|date=January 2020}} The scope of the FGED Society includes data generated using any functional genomics technology when applied to genome-scale studies of gene expression, binding, modification and other related applications.

In September 2021, the FGED Society ceased operations.{{cite web |title=History of the Functional Genomics Data Society |url=https://www.fged.org/history |website=FGED Society |access-date=13 February 2022}}

History

The FGED Society was formed in 1999 at a meeting on Microarray Gene

Expression Databases in recognition of the need to establish standards

for sharing and storing data from DNA microarray experiments.{{Citation needed|date=January 2020}} Originally named the "MGED Society," the society began with

a focus on DNA microarrays and gene expression data.

The original MGED Society was incorporated in 2002 as a non-profit

public benefit organization with the title

Microarray Gene Expression Data Society and obtained permanent

charity status in 2007.{{Citation needed|date=January 2020}} The MGED name was legally changed in 2007 to

Microarray and Gene Expression Data Society to emphasize a broader

scope.

In September 2008, the Society decided to promote itself simply as the

MGED Society to broaden the Society's scope beyond microarray technology

and gene expression applications, yet still

retain the recognized value of the MGED name within the community.{{Citation needed|date=January 2020}}

In July 2010, the society voted to change its name to the "Functional Genomics Data (FGED) Society"

to reflect its current mission which goes beyond microarrays and gene expression to encompass data

generated using any functional genomics technology applied to

genomic-scale studies of gene

expression, binding, modification (such as DNA methylation),

and other related applications. This was formally announced on 14 July 2010 at the society's "MGED13" annual meeting.{{cite web|last=FGED_Society|title=Big news: MGED has a new name: FGED – Functional Genomics Data Society|url=https://twitter.com/FGED_Society/status/18534129748|work=Twitter|accessdate=10 August 2010}}

=Presidents of the FGED Society=

Board members and officers of the FGED Society are elected annually each May and start serving in June. Presidents of the FGED Society along with their terms in office are as follows:

  • Francis Ouellette (2013–2021)
  • John Quackenbush (2011–2013)
  • Chris Stoeckert (2007–2011)
  • Catherine Ball (2003–2007)
  • Alvis Brasma (1999–2003)

Membership

The FGED Board of Directors and Advisory Board consist of volunteers

from academia, industry, government, and journals representing a

cross-section of those generating, analyzing, archiving, and

publishing in the functional genomics area.

Although there is no formal membership, the attendees of

the annual FGED meetings are considered to be part of the FGED community.

Standards

To date, FGED has produced a variety of standards specifications pertaining to DNA microarray experiments. These standards are designed to improve the annotation, communication, and sharing of data and findings from such experiments within the life science research community.

=MINSEQE=

Minimal Information about a high-throughput SEQuencing Experiment (MINSEQE) is a

data content minimum information standard that describes the essential information needed to

adequately document a high-throughput sequencing experiment for the purpose of

interpretation and replication of the results.{{cite web | author = Functional Genomics Data Society | title = Minimum Information about a high-throughput SEQuencing Experiment |date=June 2012 | url = https://www.fged.org/projects/minseqe/ }}

=MIAME=

MIAME (Minimal Information About a Microarray Experiment) is a

data content standard that describes the essential information needed to

adequately document a DNA microarray experiment for the purpose of

interpretation and replication of the results. It was the first published example of a minimum information standard for high-throughput experiments in the life sciences, and as such, laid the groundwork for similar standards in other bioscience domains.

=MAGE-OM and MAGE-TAB=

MAGE-OM (MicroArray Gene Expression

Object Model) is a data exchange and data modeling standard for use in encoding

data from microarray experiments for the purpose of export and import

into software tools and databases via XML files. MAGE-OM is a

platform-independent model implemented in the XML-based MAGE-ML

format.

A new version, MAGE-TAB, has been developed to be easier to

understand and generate by data producers as it is in a format

(tab-delimited) that can be viewed and edited using widely available

spreadsheet software, such as Microsoft Excel.{{cite web| url=https://www.fged.org/projects/mage-tab/ | title=MAGE-TAB Homepage | work=FGED Website | accessdate=2022-02-13 }}

{{Further|Sample and Data Relationship Format}}

=MGED Ontology=

The MGED Ontology (MO) provides a standard terminology for describing components of a

DNA microarray experiment.{{cite web | url=http://mged.sourceforge.net/ontologies/MO_FAQ.htm | title=The MGED Ontology FAQ | work=MO project website | accessdate=2008-11-23}}

The Ontology for Biomedical Investigations (OBI) is being developed as a replacement for the MO. A mapping of ontology terms from MO to OBI is available.{{cite web|title=Mapping terms between MO and Ontology for Biomedical Investigations|url=http://mged.sourceforge.net/ontologies/MO2OBImapping.php|publisher=MGED Ontology Working Group|accessdate=10 August 2010}}

Annual meeting

A major component of the FGED Society effort

has been the annual FGED meeting to showcase cutting-edge scientific work and promote

standards.{{cite web | url=https://www.fged.org/conferences/ | title=List of FGED annual meetings | work=FGED website | accessdate=2022-02-13}}

The FGED Society has held its annual meeting at venues around

the world since 1999, coordinating with a local scientific organization

that provides space for talks, poster sessions, workshops, and tutorials.

=Past meetings of the FGED Society=

Here is a list of the annual meeting dates and locations for past meetings of the FGED Society.{{cite web|title=FGED Society Meetings|url=https://www.fged.org/conferences|publisher=FGED Society|accessdate=13 February 2022}} All meetings from 2010 and prior were held under the name "MGED Society".

class="wikitable"
DateLocation
20 June 2013Seattle, WA, USA{{cite web |title=FGED 15th International Conference: Translational Genomics: Applications of Genomics to Clinical Diagnosis and Treatment, 20–22 June 2013 |url=http://archive.fged.org/conferences/2013-seattle/ |publisher=FGED.org |accessdate=24 September 2014 |archive-url=https://web.archive.org/web/20150919073412/http://archive.fged.org/conferences/2013-seattle/ |archive-date=19 September 2015 |url-status=dead}}
25 January 2012Boston, Massachusetts, USA{{cite web |title= Data Sharing and Integration Best Practices, 25–26 Jan 2012 (invitation only) |url=http://fged.org/conferences/data-sharing-and-integration-best-practices/ |publisher=FGED.org |accessdate=29 October 2014 |archive-url=https://web.archive.org/web/20160821151511/http://fged.org/conferences/data-sharing-and-integration-best-practices/ |archive-date=21 August 2016 |url-status=dead}}
15 July 2010Boston, Massachusetts, USA (in conjunction with ISMB)
8 October 2009Phoenix, Arizona, USA
5 September 2008Riva del Garda, Trentino, Italy
5 September 2007Brisbane, Australia
10 September 2006Seattle, WA, USA
13 September 2005Bergen, Norway
10 September 2004Toronto, Canada
5 September 2003Aix-en-Provence, France
27 September 2002Plaza Heisei, Odaiba, Tokyo, Japan
31 March 2001Stanford University, CA, USA
27 May 2000DKFZ and EMBL, Heidelberg, Germany
15 November 1999EBI, Cambridge, UK

See also

References