FGF22

{{infobox protein

|Name=fibroblast growth factor 22

|caption=

|image=

|width=

|HGNCid=3679

|Symbol=FGF22

|AltSymbols=

|EntrezGene=27006

|OMIM=605831

|RefSeq= NM_020637

|UniProt= Q9HCT0

|PDB=

|ECnumber=

|Chromosome=19

|Arm=p

|Band=13.3

|LocusSupplementaryData=

}}

Fibroblast growth factor 22 is a protein which in humans is encoded by the FGF22 gene.{{cite journal | vauthors = Umemori H, Linhoff MW, Ornitz DM, Sanes JR | title = FGF22 and its close relatives are presynaptic organizing molecules in the mammalian brain | journal = Cell | volume = 118 | issue = 2 | pages = 257–70 |date=July 2004 | pmid = 15260994 | doi = 10.1016/j.cell.2004.06.025 | s2cid = 18836066 | doi-access = free }}{{cite journal | vauthors = Zhang X, Ibrahimi OA, Olsen SK, Umemori H, Mohammadi M, Ornitz DM | title = Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family | journal = The Journal of Biological Chemistry | volume = 281 | issue = 23 | pages = 15694–700 |date=June 2006 | pmid = 16597617 | pmc = 2080618 | doi = 10.1074/jbc.M601252200 | doi-access = free }}

Function

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development.{{cite web | title = Entrez Gene: Fibroblast growth factor 22| url =https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=27006 }}

FGF22

Function

References