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FLRT2

{{Short description|Protein-coding gene in the species Homo sapiens}}

{{Infobox_gene}}

Fibronectin leucine-rich repeat transmembrane protein FLRT2 is a protein that in humans is encoded by the FLRT2 gene.{{cite journal | vauthors = Lacy SE, Bönnemann CG, Buzney EA, Kunkel LM | title = Identification of FLRT1, FLRT2, and FLRT3: a novel family of transmembrane leucine-rich repeat proteins | journal = Genomics | volume = 62 | issue = 3 | pages = 417–26 | date = December 1999 | pmid = 10644439 | doi = 10.1006/geno.1999.6033 }}{{cite journal | vauthors = Haines BP, Wheldon LM, Summerbell D, Heath JK, Rigby PW | title = Regulated expression of FLRT genes implies a functional role in the regulation of FGF signalling during mouse development | journal = Developmental Biology | volume = 297 | issue = 1 | pages = 14–25 | date = September 2006 | pmid = 16872596 | doi = 10.1016/j.ydbio.2006.04.004 | doi-access = }}{{cite web | title = Entrez Gene: FLRT2 fibronectin leucine rich transmembrane protein 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23768}}

Function

This gene encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. FLRT family members may function in cell adhesion and/or receptor signalling. Their protein structures resemble small leucine-rich proteoglycans found in the extracellular matrix.

References

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Further reading

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  • {{cite journal | vauthors = Zhang Z, Henzel WJ | title = Signal peptide prediction based on analysis of experimentally verified cleavage sites | journal = Protein Science | volume = 13 | issue = 10 | pages = 2819–24 | date = October 2004 | pmid = 15340161 | pmc = 2286551 | doi = 10.1110/ps.04682504 }}
  • {{cite journal | vauthors = Ishikawa K, Nagase T, Nakajima D, Seki N, Ohira M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O | title = Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro | journal = DNA Research | volume = 4 | issue = 5 | pages = 307–13 | date = October 1997 | pmid = 9455477 | doi = 10.1093/dnares/4.5.307 | doi-access = free }}
  • {{cite journal | vauthors = Bonaldo MF, Lennon G, Soares MB | title = Normalization and subtraction: two approaches to facilitate gene discovery | journal = Genome Research | volume = 6 | issue = 9 | pages = 791–806 | date = September 1996 | pmid = 8889548 | doi = 10.1101/gr.6.9.791 | doi-access = free }}

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