FinP
{{Infobox rfam
| Name = FinP
| image = RF00107.jpg
| width =
| caption = Predicted secondary structure and sequence conservation of FinP
| Symbol = FinP
| AltSymbols =
| Rfam = RF00107
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| RNA_type = Gene
| Tax_domain = Bacteria
| GO =
| SO = {{SO|0000644}}
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FinP encodes an antisense non-coding RNA gene that is complementary to part of the TraJ 5' UTR. The FinOP system regulates the transfer of F-like plasmids. The traJ gene encodes a protein required for transcription from the major transfer promoter, pY. The FinO protein is essential for effective repression, acting by binding to FinP and protecting it from RNase E degradation.{{cite journal | vauthors = Jerome LJ, van Biesen T, Frost LS | title = Degradation of FinP antisense RNA from F-like plasmids: the RNA-binding protein, FinO, protects FinP from ribonuclease E | journal = Journal of Molecular Biology | volume = 285 | issue = 4 | pages = 1457–1473 | date = January 1999 | pmid = 9917389 | doi = 10.1006/jmbi.1998.2404 }}{{cite journal | vauthors = Arthur DC, Ghetu AF, Gubbins MJ, Edwards RA, Frost LS, Glover JN | title = FinO is an RNA chaperone that facilitates sense-antisense RNA interactions | journal = The EMBO Journal | volume = 22 | issue = 23 | pages = 6346–6355 | date = December 2003 | pmid = 14633993 | pmc = 291848 | doi = 10.1093/emboj/cdg607 }}
References
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External links
- {{Rfam|id=RF00107|name=FinP}}
- {{Rfam|id=RF00243|name=traJ 5' UTR}}
{{molecular-cell-biology-stub}}