Folch solution

{{Short description|Solution containing chloroform and methanol}}

{{Refimprove|date=June 2016}}

A Folch solution is a solution containing chloroform and methanol, usually in a 2:1 (vol/vol) ratio.{{cite journal|last1=Folch|first1=J.|last2=Lees|first2=M.|last3=Sloan Stanley|first3=G.H.|title=A Simple Method for the Isolation and Purification of Total Lipides from Animal Tissues|journal=Journal of Biological Chemistry|date=May 1, 1957|volume=226|issue=1 |pages=497–509|doi=10.1016/S0021-9258(18)64849-5|url=http://www.jbc.org/content/226/1/497.long|doi-access=free|pmid=13428781 |url-access=subscription}} One of its uses is in separating polar from nonpolar compounds, for example separating nonpolar lipids from polar proteins and carbohydrates in blood serum.