Formate dehydrogenase-N

{{Infobox enzyme

| Name = Formate dehydrogenase-N

| EC_number = 1.1.5.6

| CAS_number =

| GO_code =

| image =

| width =

| caption =

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Formate dehydrogenase-N ({{EC number|1.1.5.6}}, Fdh-N, FdnGHI, nitrate-inducible formate dehydrogenase, formate dehydrogenase N, FDH-N, nitrate inducible Fdn, nitrate inducible formate dehydrogenase) is an enzyme with systematic name formate:quinone oxidoreductase.{{cite journal | vauthors = Enoch HG, Lester RL | title = The purification and properties of formate dehydrogenase and nitrate reductase from Escherichia coli | journal = The Journal of Biological Chemistry | volume = 250 | issue = 17 | pages = 6693–705 | date = September 1975 | doi = 10.1016/S0021-9258(19)40989-7 | doi-access = free | pmid = 1099093 }}{{cite journal | vauthors = Jormakka M, Törnroth S, Byrne B, Iwata S | title = Molecular basis of proton motive force generation: structure of formate dehydrogenase-N | journal = Science | volume = 295 | issue = 5561 | pages = 1863–8 | date = March 2002 | pmid = 11884747 | doi = 10.1126/science.1068186 | bibcode = 2002Sci...295.1863J }}{{cite journal | vauthors = Jormakka M, Törnroth S, Abramson J, Byrne B, Iwata S | title = Purification and crystallization of the respiratory complex formate dehydrogenase-N from Escherichia coli | journal = Acta Crystallographica Section D | volume = 58 | issue = Pt 1 | pages = 160–2 | date = January 2002 | pmid = 11752799 | doi = 10.1107/s0907444901017723 | bibcode = 2002AcCrD..58..160J }} This enzyme catalyses the following chemical reaction

: formate + quinone $\backslash rightleftharpoons$ CO₂ + quinol

This enzyme contains molybdopterin-guanine dinucleotides, five [4Fe-4S] clusters and two heme b groups.