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G3BP2

{{Short description|Protein-coding gene in the species Homo sapiens}}

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Ras GTPase-activating protein-binding protein 2 is an enzyme that in humans is encoded by the G3BP2 gene.{{cite journal | vauthors = Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O | display-authors = 6 | title = Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro | journal = DNA Research | volume = 5 | issue = 3 | pages = 169–76 | date = June 1998 | pmid = 9734811 | doi = 10.1093/dnares/5.3.169 | doi-access = free }}{{cite journal | vauthors = Kennedy D, Wood SA, Ramsdale T, Tam PP, Steiner KA, Mattick JS | title = Identification of a mouse orthologue of the human ras-GAP-SH3-domain binding protein and structural confirmation that these proteins contain an RNA recognition motif | journal = Biomedical Peptides, Proteins & Nucleic Acids | volume = 2 | issue = 3 | pages = 93–9 | date = June 1998 | pmid = 9575347 }}{{cite web | title = Entrez Gene: G3BP2 GTPase activating protein (SH3 domain) binding protein 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9908}}

Interactions

G3BP2 has been shown to interact with IκBα.{{cite journal | vauthors = Prigent M, Barlat I, Langen H, Dargemont C | title = IkappaBalpha and IkappaBalpha /NF-kappa B complexes are retained in the cytoplasm through interaction with a novel partner, RasGAP SH3-binding protein 2 | journal = The Journal of Biological Chemistry | volume = 275 | issue = 46 | pages = 36441–9 | date = November 2000 | pmid = 10969074 | doi = 10.1074/jbc.M004751200 | doi-access = free }}

References

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Further reading

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  • {{cite journal | vauthors = Kim MM, Wiederschain D, Kennedy D, Hansen E, Yuan ZM | title = Modulation of p53 and MDM2 activity by novel interaction with Ras-GAP binding proteins (G3BP) | journal = Oncogene | volume = 26 | issue = 29 | pages = 4209–15 | date = June 2007 | pmid = 17297477 | doi = 10.1038/sj.onc.1210212 | doi-access = | s2cid = 20028334 }}
  • {{cite journal | vauthors = Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M | title = Global, in vivo, and site-specific phosphorylation dynamics in signaling networks | journal = Cell | volume = 127 | issue = 3 | pages = 635–48 | date = November 2006 | pmid = 17081983 | doi = 10.1016/j.cell.2006.09.026 | s2cid = 7827573 | doi-access = free }}
  • {{cite journal | vauthors = Ong SE, Mittler G, Mann M | title = Identifying and quantifying in vivo methylation sites by heavy methyl SILAC | journal = Nature Methods | volume = 1 | issue = 2 | pages = 119–26 | date = November 2004 | pmid = 15782174 | doi = 10.1038/nmeth715 | s2cid = 6654604 }}
  • {{cite journal | vauthors = Ballif BA, Villén J, Beausoleil SA, Schwartz D, Gygi SP | title = Phosphoproteomic analysis of the developing mouse brain | journal = Molecular & Cellular Proteomics | volume = 3 | issue = 11 | pages = 1093–101 | date = November 2004 | pmid = 15345747 | doi = 10.1074/mcp.M400085-MCP200 | doi-access = free }}
  • {{cite journal | vauthors = Prigent M, Barlat I, Langen H, Dargemont C | title = IkappaBalpha and IkappaBalpha /NF-kappa B complexes are retained in the cytoplasm through interaction with a novel partner, RasGAP SH3-binding protein 2 | journal = The Journal of Biological Chemistry | volume = 275 | issue = 46 | pages = 36441–9 | date = November 2000 | pmid = 10969074 | doi = 10.1074/jbc.M004751200 | doi-access = free }}
  • {{cite journal | vauthors = Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA | display-authors = 6 | title = Large-scale concatenation cDNA sequencing | journal = Genome Research | volume = 7 | issue = 4 | pages = 353–8 | date = April 1997 | pmid = 9110174 | pmc = 139146 | doi = 10.1101/gr.7.4.353 }}
  • {{cite journal | vauthors = Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA | title = A "double adaptor" method for improved shotgun library construction | journal = Analytical Biochemistry | volume = 236 | issue = 1 | pages = 107–13 | date = April 1996 | pmid = 8619474 | doi = 10.1006/abio.1996.0138 }}

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