GJA10

{{Short description|Protein-coding gene in the species Homo sapiens}}

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Gap junction alpha-10 protein, also known as connexin-62 (Cx62), is a protein that in humans is encoded by the GJA10 gene.{{cite web | title = Entrez Gene: gap junction protein| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=84694}}

Connexins, such as GJA10, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits.{{cite journal |vauthors=Söhl G, Nielsen PA, Eiberger J, Willecke K | title = Expression profiles of the novel human connexin genes hCx30.2, hCx40.1, and hCx62 differ from their putative mouse orthologues | journal = Cell Commun. Adhes. | volume = 10 | issue = 1 | pages = 27–36 | year = 2003 | pmid = 12881038 | doi = 10.1080/15419060302063| s2cid = 225894 }}

References

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Further reading

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  • {{cite journal |vauthors=Hosgood HD, Zhang L, Shen M |title=Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. |journal=Occup Environ Med |volume=66 |issue= 12 |pages= 848–53 |year= 2009 |pmid= 19773279 |doi= 10.1136/oem.2008.044024 |pmc=2928224|display-authors=etal}}

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{{Ion channels|g4}}

Category:Integral membrane proteins

{{Gene-6-stub}}

Category:Connexins