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GPR4

{{Short description|Protein-coding gene in the species Homo sapiens}}

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G-protein coupled receptor 4 is a protein that in humans is encoded by the GPR4 gene.{{cite journal |vauthors=Mahadevan MS, Baird S, Bailly JE, Shutler GG, Sabourin LA, Tsilfidis C, Neville CE, Narang M, Korneluk RG | title = Isolation of a novel G protein-coupled receptor (GPR4) localized to chromosome 19q13.3 | journal = Genomics | volume = 30 | issue = 1 | pages = 84–8 |date=Apr 1996 | pmid = 8595909 | doi = 10.1006/geno.1995.0013 }}{{cite web | title = Entrez Gene: GPR4 G protein-coupled receptor 4| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2828}}

See also

References

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Further reading

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  • {{cite journal |vauthors=An S, Tsai C, Goetzl EJ |title=Cloning, sequencing and tissue distribution of two related G protein-coupled receptor candidates expressed prominently in human lung tissue. |journal=FEBS Lett. |volume=375 |issue= 1–2 |pages= 121–4 |year= 1996 |pmid= 7498459 |doi=10.1016/0014-5793(95)01196-L |s2cid=9845527 |doi-access=free }}
  • {{cite journal | author=Heiber M |title=Isolation of three novel human genes encoding G protein-coupled receptors |journal=DNA Cell Biol. |volume=14 |issue= 1 |pages= 25–35 |year= 1995 |pmid= 7832990 |doi=10.1089/dna.1995.14.25 | author2=Docherty JM | author3=Shah G | last4=Nguyen | first4=Tuan | last5=Cheng | first5=Regina | last6=Heng | first6=Henry H.Q. | last7=Marchese | first7=Adriano | last8=Tsui | first8=LAP-Chee | last9=Shi | first9=Xiaomei }}
  • {{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 | author2=Feingold EA | author3=Grouse LH | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD |bibcode=2002PNAS...9916899M |doi-access=free }}
  • {{cite journal | author=Lum H |title=Inflammatory stress increases receptor for lysophosphatidylcholine in human microvascular endothelial cells |journal=Am. J. Physiol. Heart Circ. Physiol. |volume=285 |issue= 4 |pages= H1786–9 |year= 2003 |pmid= 12805023 |doi= 10.1152/ajpheart.00359.2003 | author2=Qiao J | author3=Walter RJ | last4=Huang | first4=F | last5=Subbaiah | first5=PV | last6=Kim | first6=KS | last7=Holian | first7=O }}
  • {{cite journal | author=Ludwig MG |title=Proton-sensing G-protein-coupled receptors |journal=Nature |volume=425 |issue= 6953 |pages= 93–8 |year= 2003 |pmid= 12955148 |doi= 10.1038/nature01905 | author2=Vanek M | author3=Guerini D | last4=Gasser | first4=Jürg A. | last5=Jones | first5=Carol E. | last6=Junker | first6=Uwe | last7=Hofstetter | first7=Hans | last8=Wolf | first8=Romain M. | last9=Seuwen | first9=Klaus |bibcode=2003Natur.425...93L |s2cid=4395698 }}
  • {{cite journal | author=Bektas M |title=The G protein-coupled receptor GPR4 suppresses ERK activation in a ligand-independent manner |journal=Biochemistry |volume=42 |issue= 42 |pages= 12181–91 |year= 2003 |pmid= 14567679 |doi= 10.1021/bi035051y | author2=Barak LS | author3=Jolly PS | last4=Liu | first4=Hong | last5=Lynch | first5=Kevin R. | last6=Lacana | first6=Emanuela | last7=Suhr | first7=Ki-Beom | last8=Milstien | first8=Sheldon | last9=Spiegel | first9=Sarah }}
  • {{cite journal | author=Sin WC |title=G protein-coupled receptors GPR4 and TDAG8 are oncogenic and overexpressed in human cancers |journal=Oncogene |volume=23 |issue= 37 |pages= 6299–303 |year= 2004 |pmid= 15221007 |doi= 10.1038/sj.onc.1207838 | author2=Zhang Y | author3=Zhong W | last4=Adhikarakunnathu | first4=Sree | last5=Powers | first5=Scott | last6=Hoey | first6=Tim | last7=An | first7=Songzhu | last8=Yang | first8=Jianxin |s2cid=23448180 | doi-access= }}
  • {{cite journal | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 | author2=Wagner L | author3=Feingold EA | last4=Shenmen | first4=CM | last5=Grouse | first5=LH | last6=Schuler | first6=G | last7=Klein | first7=SL | last8=Old | first8=S | last9=Rasooly | first9=R }}
  • {{cite journal | author=Kim KS |title=GPR4 plays a critical role in endothelial cell function and mediates the effects of sphingosylphosphorylcholine |journal=FASEB J. |volume=19 |issue= 7 |pages= 819–21 |year= 2005 |pmid= 15857892 |doi= 10.1096/fj.04-2988fje | author2=Ren J | author3=Jiang Y | last4=Ebrahem | first4=Q | last5=Tipps | first5=R | last6=Cristina | first6=K | last7=Xiao | first7=YJ | last8=Qiao | first8=J | last9=Taylor | first9=KL |doi-access=free |s2cid=23640250 }}
  • {{cite journal | author=Qiao J |title=Lysophosphatidylcholine impairs endothelial barrier function through the G protein-coupled receptor GPR4 |journal=Am. J. Physiol. Lung Cell Mol. Physiol. |volume=291 |issue= 1 |pages= L91–101 |year= 2006 |pmid= 16461426 |doi= 10.1152/ajplung.00508.2005 | author2=Huang F | author3=Naikawadi RP | last4=Kim | first4=KS | last5=Said | first5=T | last6=Lum | first6=H |s2cid=25149978 }}
  • {{cite journal | author=Huang F |title=A novel lysophospholipid- and pH-sensitive receptor, GPR4, in brain endothelial cells regulates monocyte transmigration |journal=Endothelium |volume=14 |issue= 1 |pages= 25–34 |year= 2007 |pmid= 17364894 |doi= 10.1080/10623320601177288 | author2=Mehta D | author3=Predescu S | last4=Kim | first4=Kwang | last5=Lum | first5=Hazel |hdl=2027.42/78980 |hdl-access=free }}
  • {{cite journal | author=Zou Y |title=Upregulation of endothelial adhesion molecules by lysophosphatidylcholine. Involvement of G protein-coupled receptor GPR4 |journal=FEBS J. |volume=274 |issue= 10 |pages= 2573–84 |year= 2007 |pmid= 17437524 |doi= 10.1111/j.1742-4658.2007.05792.x | author2=Kim CH | author3=Chung JH | last4=Kim | first4=Ji Y. | last5=Chung | first5=Sang W. | last6=Kim | first6=Mi K. | last7=Im | first7=Dong S. | last8=Lee | first8=Jaewon | last9=Yu | first9=Byung P. |s2cid=83245004 | doi-access=free }}
  • {{cite journal | author=Tobo M |title=Previously postulated "ligand-independent" signaling of GPR4 is mediated through proton-sensing mechanisms |journal=Cell. Signal. |volume=19 |issue= 8 |pages= 1745–53 |year= 2007 |pmid= 17462861 |doi= 10.1016/j.cellsig.2007.03.009 | author2=Tomura H | author3=Mogi C | last4=Wang | first4=J | last5=Liu | first5=J | last6=Komachi | first6=M | last7=Damirin | first7=A | last8=Kimura | first8=T | last9=Murata | first9=N }}

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{{G protein-coupled receptors}}

Category:G protein-coupled receptors

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