GPR61

{{Short description|Protein-coding gene in the species Homo sapiens}}

Probable G-protein coupled receptor 61 is a protein that in humans is encoded by the GPR61 gene.{{cite journal |vauthors=Lee DK, George SR, Cheng R, Nguyen T, Liu Y, Brown M, Lynch KR, O'Dowd BF | title = Identification of four novel human G protein-coupled receptors expressed in the brain | journal = Brain Res Mol Brain Res | volume = 86 | issue = 1–2 | pages = 13–22 |date=Feb 2001 | pmid = 11165367 | doi =10.1016/S0169-328X(00)00242-4 }}{{cite journal |vauthors=Cikos S, Gregor P, Koppel J | title = Cloning of a novel biogenic amine receptor-like G protein-coupled receptor expressed in human brain | journal = Biochim Biophys Acta | volume = 1521 | issue = 1–3 | pages = 66–72 |date=Nov 2001 | pmid = 11690637 | doi = 10.1016/s0167-4781(01)00289-5}}{{cite web | title = Entrez Gene: GPR61 G protein-coupled receptor 61| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=83873}}

This gene belongs to the G-protein coupled receptor 1 family. G protein-coupled receptors contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. The protein encoded by this gene is most closely related to biogenic amine receptors.

References

{{cite journal |title=The DNA sequence and biological annotation of human chromosome 1 |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727 |display-authors=3 |author1=Gregory SG |author2=Barlow KF |author3=McLay KE |name-list-style=vanc |last4=Kaul |first4=R |last5=Swarbreck |first5=D |last6=Dunham |first6=A |last7=Scott |first7=CE |last8=Howe |first8=KL |last9=Woodfine |first9=K |bibcode=2006Natur.441..315G |doi-access=free }}
{{cite journal |title=Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 |display-authors=3 |author1=Kimura K |author2=Wakamatsu A |author3=Suzuki Y |name-list-style=vanc |last4=Ota |first4=T |last5=Nishikawa |first5=T |last6=Yamashita |first6=R |last7=Yamamoto |first7=J |last8=Sekine |first8=M |last9=Tsuritani |first9=K |pmc=1356129 }}
{{cite journal |title=A key role for transmembrane prolines in calcitonin receptor-like receptor agonist binding and signalling: implications for family B G-protein-coupled receptors |journal=Mol. Pharmacol. |volume=67 |issue= 1 |pages= 20–31 |year= 2005 |pmid= 15615699 |doi= 10.1124/mol.67.1.20|display-authors=3 |author1=Conner AC |author2=Hay DL |author3=Simms J |name-list-style=vanc |last4=Howitt |first4=SG |last5=Schindler |first5=M |last6=Smith |first6=DM |last7=Wheatley |first7=M |last8=Poyner |first8=DR |s2cid=22535315 }}
{{cite journal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 |display-authors=3 |author1=Gerhard DS |author2=Wagner L |author3=Feingold EA |name-list-style=vanc |last4=Shenmen |first4=CM |last5=Grouse |first5=LH |last6=Schuler |first6=G |last7=Klein |first7=SL |last8=Old |first8=S |last9=Rasooly |first9=R |pmc=528928 }}
{{cite journal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 |display-authors=3 |author1=Strausberg RL |author2=Feingold EA |author3=Grouse LH |name-list-style=vanc |last4=Derge |first4=JG |last5=Klausner |first5=RD |last6=Collins |first6=FS |last7=Wagner |first7=L |last8=Shenmen |first8=CM |last9=Schuler |first9=GD |pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
{{cite journal |title=Identification of G protein-coupled receptor genes from the human genome sequence |journal=FEBS Lett. |volume=520 |issue= 1–3 |pages= 97–101 |year= 2002 |pmid= 12044878 |doi=10.1016/S0014-5793(02)02775-8 |display-authors=3 |author1=Takeda S |author2=Kadowaki S |author3=Haga T |name-list-style=vanc |last4=Takaesu |first4=H |last5=Mitaku |first5=S |s2cid=7116392 |doi-access=free }}

GPR61

References

Further reading

See also