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GPR78

{{Short description|Protein-coding gene in the species Homo sapiens}}

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Probable G-protein coupled receptor 78 is a protein that in humans is encoded by the GPR78 gene.{{cite journal |vauthors=Lee DK, Nguyen T, Lynch KR, Cheng R, Vanti WB, Arkhitko O, Lewis T, Evans JF, George SR, O'Dowd BF | title = Discovery and mapping of ten novel G protein-coupled receptor genes | journal = Gene | volume = 275 | issue = 1 | pages = 83–91 |date=Sep 2001 | pmid = 11574155 | doi =10.1016/S0378-1119(01)00651-5 }}{{cite web | title = Entrez Gene: GPR78 G protein-coupled receptor 78| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=27201}}

G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[supplied by OMIM]

References

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Further reading

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  • {{cite journal | author=van Laar T |title=The novel MMS-inducible gene Mif1/KIAA0025 is a target of the unfolded protein response pathway |journal=FEBS Lett. |volume=469 |issue= 1 |pages= 123–31 |year= 2000 |pmid= 10708769 |doi=10.1016/S0014-5793(00)01253-9 | author2=Schouten T | author3=Hoogervorst E | last4=Van Eck | first4=M | last5=Van Der Eb | first5=AJ | last6=Terleth | first6=C |s2cid=6419566 |doi-access=free}}
  • {{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 | author2=Feingold EA | author3=Grouse LH | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD |bibcode=2002PNAS...9916899M |doi-access=free }}
  • {{cite journal | author=Clark HF |title=The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003 | pmc=403697 | author2=Gurney AL | author3=Abaya E | last4=Baker | first4=K | last5=Baldwin | first5=D | last6=Brush | first6=J | last7=Chen | first7=J | last8=Chow | first8=B | last9=Chui | first9=C }}
  • {{cite journal | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 | author2=Wagner L | author3=Feingold EA | last4=Shenmen | first4=CM | last5=Grouse | first5=LH | last6=Schuler | first6=G | last7=Klein | first7=SL | last8=Old | first8=S | last9=Rasooly | first9=R }}
  • {{cite journal | author=Underwood SL |title=Association analysis of the chromosome 4p-located G protein-coupled receptor 78 (GPR78) gene in bipolar affective disorder and schizophrenia |journal=Mol. Psychiatry |volume=11 |issue= 4 |pages= 384–94 |year= 2006 |pmid= 16389273 |doi= 10.1038/sj.mp.4001786 | author2=Christoforou A | author3=Thomson PA | last4=Wray | first4=N R | last5=Tenesa | first5=A | last6=Whittaker | first6=J | last7=Adams | first7=R A | last8=Le Hellard | first8=S | last9=Morris | first9=S W |s2cid=12678399 | doi-access= }}

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{{G protein-coupled receptors}}

Category:G protein-coupled receptors

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