GTO

• Great Teacher Onizuka, a manga, anime, live-action series, and film
• GameTable Online, a game portal

• GTO (band), an Australian band
• The GTOs, an American girl group
• Giraffe Tongue Orchestra, an American band
• Greater Than One, an English electronic music band

• GTO: Gangsters Takin' Over, an album by Oran "Juice" Jones
• GTO Records, a British record label
• "GTO" (Ronny & the Daytonas song), 1964
• "GTO" (Sinitta song), 1987
• "GTO", a 2017 song by Europe from the album Walk the Earth

• Gate turn-off thyristor
• Gaussian-type orbital
• Geostationary transfer orbit
• Golgi tendon organ

• Gorton railway station, in Greater Manchester, England
• Jalaluddin Airport (IATA: GTO) in Gorontalo, Indonesia
• Grand Touring Over, a category for production cars
• Gran Turismo Omologata, a model name of several grand tourer automobiles:
• Ferrari 250 GTO
• Ferrari 288 GTO
• Ferrari 599 GTO
• Pontiac GTO
• Mitsubishi 3000GT (Mitsubishi GTO in Japan)
• Mitsubishi Galant GTO
• HSV GTO

• Geographic targeting order issued by the United States Secretary of Treasury
• Guanajuato, Mexico
• Ready for Labour and Defence of the USSR (Russian: {{lang|ru|Готов к труду и обороне СССР}}, Gotov k trudu i oborone SSSR), a Soviet physical training programme

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