Generalized Anxiety Disorder 7

{{Short description|Anxiety disorder screening instrument}}

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| name = Generalized Anxiety Disorder 7 item

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| synonyms = GAD-7

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| LOINC = {{LOINC|69737-5}}

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The Generalized Anxiety Disorder 7-item scale (GAD-7) is a widely used self-administered diagnostic tool designed to screen for and assess the severity of generalized anxiety disorder (GAD).{{cite journal | vauthors = Spitzer RL, Kroenke K, Williams JB, Löwe B | title = A brief measure for assessing generalized anxiety disorder: the GAD-7 | journal = Archives of Internal Medicine | volume = 166 | issue = 10 | pages = 1092–1097 | date = May 2006 | pmid = 16717171 | doi = 10.1001/archinte.166.10.1092 | authorlink1 = Robert Spitzer (psychiatrist) | doi-access = free | authorlink3 = Janet B. W. Williams }} Comprising seven items, the GAD-7 measures the frequency of anxiety symptoms over the past two weeks, with respondents rating each item on a scale from "not at all" to "nearly every day." The GAD-7 was developed in 2006 by Robert L. Spitzer, Janet B.W. Williams, Kurt Kroenke, and Bernd Löwe as a brief self-report questionnaire designed to assess symptoms associated with generalized anxiety disorder.{{Cite web |title=GAD-7 Anxiety Test {{!}} Clinically Validated Self-Assessment for Anxiety |url=https://anxietychecklist.com/anxiety-test/gad-7 |access-date=2025-05-24 |website=anxietychecklist.com |language=en}} It has been used in clinical and research settings for screening purposes and for monitoring symptom changes over time. It is valued for its simplicity, reliability, and validity in detecting anxiety symptoms in diverse populations.

The GAD-7 is normally used in outpatient and primary care settings for referral to a psychiatrist pending outcome.{{cite journal | vauthors = Löwe B, Decker O, Müller S, Brähler E, Schellberg D, Herzog W, Herzberg PY | title = Validation and standardization of the Generalized Anxiety Disorder Screener (GAD-7) in the general population | journal = Medical Care | volume = 46 | issue = 3 | pages = 266–274 | date = March 2008 | pmid = 18388841 | doi = 10.1097/mlr.0b013e318160d093 | s2cid = 16052239 }}{{Cite journal |date=2020-05-21 |title=Using Generalized Anxiety Disorder-2 (GAD-2) and GAD-7 in a Primary Care Setting |journal=Cureus |volume=12 |issue=5 |pages=e8224 |doi=10.7759/cureus.8224 |doi-access=free |issn=2168-8184 |pmc=7306644 |pmid=32582485 | vauthors = Sapra A, Bhandari P, Sharma S, Chanpura T, Lopp L }} A systematic review compared screening tools and concluded that the GAD-7 is the most efficient one for identifying GAD as well as panic disorders in primary care populations.{{cite journal | vauthors = Herr NR, Williams JW, Benjamin S, McDuffie J | title = Does this patient have generalized anxiety or panic disorder?: The Rational Clinical Examination systematic review | journal = JAMA | volume = 312 | issue = 1 | pages = 78–84 | date = July 2014 | pmid = 25058220 | doi = 10.1001/jama.2014.5950 }}

Criteria

The GAD-7 has seven items, which measure severity of various signs of GAD according to reported response categories with assigned points. The GAD-7 items include:

  1. Nervousness
  2. Inability to stop worrying
  3. Excessive worry
  4. Restlessness
  5. Difficulty in relaxing
  6. Easy irritation
  7. Fear of something awful happening{{cite journal | vauthors = Zhong QY, Gelaye B, Zaslavsky AM, Fann JR, Rondon MB, Sánchez SE, Williams MA | title = Diagnostic Validity of the Generalized Anxiety Disorder - 7 (GAD-7) among Pregnant Women | journal = PLOS ONE | volume = 10 | issue = 4 | pages = e0125096 | date = 2015-04-27 | pmid = 25915929 | pmc = 4411061 | doi = 10.1371/journal.pone.0125096 | bibcode = 2015PLoSO..1025096Z | doi-access = free }}

Response options range from “not at all” (= 0 points), “several days” (= 1 point), “more than half the days” (= 2 points), and “nearly every day” (= 3 points) with a score range from 0-21 points.

Interpretation of results

The assessment is indicated by the total score, which is made up by adding together the scores for the scale of all seven items, with responses getting 0 to 3 points:

  • Not at all (0 points)
  • Several days (1 point)
  • More than half the days (2 points)
  • Nearly every day (3 points){{cite journal | vauthors = Swinson RP | title = The GAD-7 scale was accurate for diagnosing generalised anxiety disorder | journal = Evidence-Based Medicine | volume = 11 | issue = 6 | pages = 184 | date = December 2006 | pmid = 17213178 | doi = 10.1136/ebm.11.6.184 | s2cid = 42283551 }}

The normative data enable users of the GAD-7 to discern whether an individual's anxiety score is normal, or mildly, moderately, or severely elevated.{{cite journal | vauthors = Löwe B, Decker O, Müller S, Brähler E, Schellberg D, Herzog W, Herzberg PY | title = Validation and standardization of the Generalized Anxiety Disorder Screener (GAD-7) in the general population | journal = Medical Care | volume = 46 | issue = 3 | pages = 266–274 | date = March 2008 | pmid = 18388841 | doi = 10.1097/MLR.0b013e318160d093 | s2cid = 16052239 | jstor = 40221654 }} However, while the GAD-7 seem to be able to provide probable cases of GAD, it cannot be used as replacement for clinical assessment and additional evaluation should be used to confirm a diagnosis of GAD.{{cite book | vauthors = Dugas MJ, Charette CA, Gervais NJ |editor-first1=John |editor-first2=Eric J. |editor-last1=Hunsley |editor-last2=Mash |title=A Guide to Assessments That Work |chapter=Generalized Anxiety Disorder | edition = 2nd |date=2018 |pages=293–310 |publisher=Oxford University Press |doi=10.1093/med-psych/9780190492243.003.0014 |isbn=978-0-19-049224-3 }}

class="wikitable"

|+

!Score

!Risk Level

!Suggested Intervention

0–4

|No to Low risk

|None

5–9

|Mild

|Repeat on follow-up

10–14

|Moderate

|Further evaluation required. Consider adjusting treatment plan.

15+

|Severe

|Adjust treatment plan. Higher level of care needed. Pharmacology re-evaluation.

Reliability and validity

The GAD-7 was originally validated in a primary care sample and a cutoff score of 10 (which the authors considered optimal) had a sensitivity value of 0.89 and a specificity value of 0.82 for identifying GAD. The authors of the questionnaire also found acceptable sensitivity and specificity values when the questionnaire was used as a general screen to identify other anxiety disorders (Panic Disorder, Social Anxiety, and PTSD) (GAD-7, score ≥ 8: sensitivity: 0.77, specificity: 0.82).{{cite journal | vauthors = Plummer F, Manea L, Trepel D, McMillan D | title = Screening for anxiety disorders with the GAD-7 and GAD-2: a systematic review and diagnostic metaanalysis | journal = General Hospital Psychiatry | volume = 39 | pages = 24–31 | date = 2016-03-01 | pmid = 26719105 | doi = 10.1016/j.genhosppsych.2015.11.005 }}

The GAD-7 has further been studied and validated in numerous other samples and settings.{{cite journal | vauthors = Kroenke K, Spitzer RL, Williams JB, Löwe B | title = The Patient Health Questionnaire Somatic, Anxiety, and Depressive Symptom Scales: a systematic review | journal = General Hospital Psychiatry | volume = 32 | issue = 4 | pages = 345–359 | date = 2010-07-01 | pmid = 20633738 | doi = 10.1016/j.genhosppsych.2010.03.006 }} It has been shown to correlate with other measures of anxiety and has been considered superior to other questionnaires.{{cite journal | vauthors = Dear BF, Titov N, Sunderland M, McMillan D, Anderson T, Lorian C, Robinson E | title = Psychometric comparison of the generalized anxiety disorder scale-7 and the Penn State Worry Questionnaire for measuring response during treatment of generalised anxiety disorder | journal = Cognitive Behaviour Therapy | volume = 40 | issue = 3 | pages = 216–227 | date = September 2011 | pmid = 21770844 | doi = 10.1080/16506073.2011.582138 }}{{cite journal | vauthors = Simpson W, Glazer M, Michalski N, Steiner M, Frey BN | title = Comparative efficacy of the generalized anxiety disorder 7-item scale and the Edinburgh Postnatal Depression Scale as screening tools for generalized anxiety disorder in pregnancy and the postpartum period | journal = Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie | volume = 59 | issue = 8 | pages = 434–440 | date = August 2014 | pmid = 25161068 | pmc = 4143300 | doi = 10.1177/070674371405900806 }}{{cite journal | vauthors = Peters L, Peters A, Andreopoulos E, Pollock N, Pande RL, Mochari-Greenberger H | title = Comparison of DASS-21, PHQ-8, and GAD-7 in a virtual behavioral health care setting | journal = Heliyon | volume = 7 | issue = 3 | pages = e06473 | date = March 2021 | pmid = 33817367 | pmc = 8010403 | doi = 10.1016/j.heliyon.2021.e06473 | doi-access = free | bibcode = 2021Heliy...706473P }} The GAD-7 has been evaluated in samples of both children and young individuals{{cite journal | vauthors = Guzick A, Storch EA, Smárason O, Minhajuddin A, Drummond K, Riddle D, Hettema JM, Mayes TL, Pitts S, Dodd C, Trivedi MH | title = Psychometric properties of the GAD-7 and PROMIS-Anxiety-4a among youth with depression and suicidality: Results from the Texas youth depression and suicide research network | journal = Journal of Psychiatric Research | volume = 170 | pages = 237–244 | date = February 2024 | pmid = 38169247 | doi = 10.1016/j.jpsychires.2023.12.033 }} as well as older adults.{{cite journal | vauthors = Wild B, Eckl A, Herzog W, Niehoff D, Lechner S, Maatouk I, Schellberg D, Brenner H, Müller H, Löwe B | title = Assessing generalized anxiety disorder in elderly people using the GAD-7 and GAD-2 scales: results of a validation study | journal = The American Journal of Geriatric Psychiatry | volume = 22 | issue = 10 | pages = 1029–1038 | date = October 2014 | pmid = 23768681 | doi = 10.1016/j.jagp.2013.01.076 }} It has been used in more than 2500 peer reviewed publications indexed in PubMed (current search [https://pubmed.ncbi.nlm.nih.gov/?term=%28%22anxiety%22%5BMeSH+Terms%5D+OR+%22anxiety%22%5BAll+Fields%5D+OR+%22anxieties%22%5BAll+Fields%5D+OR+%22anxiety+s%22%5BAll+Fields%5D%29+AND+%22gad7%22%5BAll+Fields%5D&sort= here]). The consensus is that it can efficient tool for screening for GAD and assessing its severity in clinical practice and research.{{cite journal | vauthors = Spitzer RL, Kroenke K, Williams JB, Löwe B | title = A brief measure for assessing generalized anxiety disorder: the GAD-7 | journal = Archives of Internal Medicine | volume = 166 | issue = 10 | pages = 1092–1097 | date = May 2006 | pmid = 16717171 | doi = 10.1001/archinte.166.10.1092 | doi-access = free }}{{Cite journal |last1=Spitzer |first1=Robert L. |last2=Kroenke |first2=Kurt |last3=Williams |first3=Janet B. W. |last4=Löwe |first4=Bernd |date=2006-05-22 |title=A Brief Measure for Assessing Generalized Anxiety Disorder: The GAD-7 |url=https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/410326 |journal=Archives of Internal Medicine |volume=166 |issue=10 |pages=1092–1097 |doi=10.1001/archinte.166.10.1092 |pmid=16717171 |issn=0003-9926|url-access=subscription }} A meta-analysis found that it achieved acceptable accuracy at a cutoff point of 8 (sensitivity of 0.83, specificity: 0.84, pooling 12 samples and 5223 participants).{{cite journal | vauthors = Plummer F, Manea L, Trepel D, McMillan D | title = Screening for anxiety disorders with the GAD-7 and GAD-2: a systematic review and diagnostic metaanalysis | journal = General Hospital Psychiatry | volume = 39 | pages = 24–31 | date = 2016 | pmid = 26719105 | doi = 10.1016/j.genhosppsych.2015.11.005 }}

The use of sumscores (i.e. summing the scores of each item) is supported by psychometric studies in some contexts, but using techniques based on factor analysis are deemed more precise.{{cite journal | vauthors = De Man J, Absetz P, Sathish T, Desloge A, Haregu T, Oldenburg B, Johnson LC, Thankappan KR, Williams ED | title = Are the PHQ-9 and GAD-7 Suitable for Use in India? A Psychometric Analysis | journal = Frontiers in Psychology | volume = 12 | pages = 676398 | date = 2021-05-13 | pmid = 34054677 | pmc = 8155718 | doi = 10.3389/fpsyg.2021.676398 | doi-access = free }}

See also

References