Genetic algebra

In mathematical genetics, a genetic algebra is a (possibly non-associative) algebra used to model inheritance in genetics. Some variations of these algebras are called train algebras, special train algebras, gametic algebras, Bernstein algebras, copular algebras, zygotic algebras, and baric algebras (also called weighted algebra). The study of these algebras was started by {{harvs|txt|authorlink=Ivor Malcolm Haddon Etherington|last=Ivor Etherington|year=1939}}.

In applications to genetics, these algebras often have a basis corresponding to the genetically different gametes, and the structure constants of the algebra encode the probabilities of producing offspring of various types. The laws of inheritance are then encoded as algebraic properties of the algebra.

For surveys of genetic algebras see {{harvtxt|Bertrand|1966}}, {{harvtxt|Wörz-Busekros|1980}} and {{harvtxt|Reed|1997}}.

Baric algebras

Baric algebras (or weighted algebras) were introduced by {{harvtxt|Etherington|1939}}. A baric algebra over a field K is a possibly non-associative algebra over K together with a homomorphism w, called the weight, from the algebra to K.{{citation | last1=González | first1=S. | last2=Martínez | first2=C. | chapter=About Bernstein algebras | zbl=1005.17021 | editor1-last=Granja | editor1-first=Ángel | title=Ring theory and algebraic geometry. Proceedings of the 5th international conference on algebra and algebraic geometry, SAGA V, León, Spain | location=New York, NY | publisher=Marcel Dekker | series=Lect. Notes Pure Appl. Math. | volume=221 | pages=223–239 | year=2001 }}

Bernstein algebras

A Bernstein algebra, based on the work of {{harvs|txt|first=Sergei Natanovich |last=Bernstein|authorlink=Sergei Natanovich Bernstein|year=1923}} on the Hardy–Weinberg law in genetics, is a (possibly non-associative) baric algebra B over a field K with a weight homomorphism w from B to K satisfying (x^2)^2 = w(x)^2 x^2. Every such algebra has idempotents e of the form e = a^2 with w(a)=1. The Peirce decomposition of B corresponding to e is

: B = Ke \oplus U_e \oplus Z_e

where U_e = \{ a \in \ker w : ea = a/2 \} and Z_e = \{ a \in \ker w : ea = 0 \}. Although these subspaces depend on e, their dimensions are invariant and constitute the type of B. An exceptional Bernstein algebra is one with U_e^2 = 0.{{cite book | last=Catalan | first=A. | chapter=E-ideals in Bernstein algebras | zbl=0968.17013 | editor-last=Costa | editor-first=Roberto | title=Nonassociative algebra and its applications. Proceedings of the fourth international conference, São Paulo, Brazil. | location=New York, NY | publisher=Marcel Dekker | series=Lect. Notes Pure Appl. Math. | volume=211| pages=35–42 | year=2000 }}

Copular algebras

Copular algebras were introduced by {{harvtxt|Etherington|1939|loc=section 8}}

Evolution algebras

An evolution algebra over a field is an algebra with a basis on which multiplication is defined by the product of distinct basis terms being zero and the square of each basis element being a linear form in basis elements. A real evolution algebra is one defined over the reals: it is non-negative if the structure constants in the linear form are all non-negative.Tian (2008) p.18 An evolution algebra is necessarily commutative and flexible but not necessarily associative or power-associative.Tian (2008) p.20

Gametic algebras

A gametic algebra is a finite-dimensional real algebra for which all structure constants lie between 0 and 1.{{cite book | page=56 | title=Introduction to Ring Theory | series=Springer Undergraduate Mathematics Series | issn=1615-2085 | first=Paul M. | last=Cohn | authorlink=Paul Cohn | publisher=Springer-Verlag | year=2000 | isbn=1852332069}}

Genetic algebras

Genetic algebras were introduced by {{harvtxt|Schafer|1949}} who showed that special train algebras are genetic algebras and genetic algebras are train algebras.

Special train algebras

Special train algebras were introduced by {{harvtxt|Etherington|1939|loc=section 4}} as special cases of baric algebras.

A special train algebra is a baric algebra in which the kernel N of the weight function is nilpotent and the principal powers of N are ideals.

{{harvtxt|Etherington|1941}} showed that special train algebras are train algebras.

Train algebras

Train algebras were introduced by {{harvtxt|Etherington|1939|loc=section 4}} as special cases of baric algebras.

Let c_1, \ldots, c_n be elements of the field K with 1 + c_1 + \cdots + c_n = 0. The formal polynomial

:x^n + c_1 w(x)x^{n-1} + \cdots + c_n w(x)^n

is a train polynomial. The baric algebra B with weight w is a train algebra if

:a^n + c_1 w(a)a^{n-1} + \cdots + c_n w(a)^n = 0

for all elements a \in B, with a^k defined as principal powers, (a^{k-1})a.{{cite journal | last=Catalán S. | first=Abdón |title=E-ideals in baric algebras | zbl=0868.17023 | journal=Mat. Contemp | volume=6 | pages=7–12 | year=1994 }}

Zygotic algebras

Zygotic algebras were introduced by {{harvtxt|Etherington|1939|loc=section 7}}

References

{{reflist}}

  • {{citation|first=S. N. |last=Bernstein|title=Principe de stationarité et généralisation de la loi de Mendel|journal=C. R. Acad. Sci. Paris|volume= 177 |year=1923|pages= 581–584}}.
  • {{Citation | last1=Bertrand | first1=Monique | title=Algèbres non associatives et algèbres génétiques | publisher=Gauthier-Villars Éditeur, Paris | series=Mémorial des Sciences Mathématiques, Fasc. 162 | mr=0215885 | year=1966}}
  • {{Citation|last1=Etherington |first1=I. M. H. |title=Genetic algebras |mr=0000597 |zbl=0027.29402 |year=1939 |journal=Proc. R. Soc. Edinburgh |volume=59 |pages=242–258 |doi=10.1017/S0370164600012323 |url=http://math.usask.ca/~bremner/research/geneticalgebras/etherington/ga.pdf |url-status=dead |archiveurl=https://web.archive.org/web/20110706211658/http://math.usask.ca/~bremner/research/geneticalgebras/etherington/ga.pdf |archivedate=2011-07-06 }}
  • {{Citation | last1=Etherington | first1=I. M. H. | title=Special train algebras | doi=10.1093/qmath/os-12.1.1 | mr=0005111 | zbl=0027.29401 | jfm=67.0093.04 | year=1941 | journal=The Quarterly Journal of Mathematics |series=Second Series | issn=0033-5606 | volume=12 | pages=1–8}}
  • {{eom|oldid=16709 |title=Bernstein problem in mathematical genetics |first=Yu.I. |last=Lyubich}}
  • {{eom|oldid=16628|first=A.|last=Micali|title=Baric algebra}}
  • {{eom|oldid=11704|first=A.|last=Micali|title=Bernstein algebra}}
  • {{Citation | last1=Reed | first1=Mary Lynn | title=Algebraic structure of genetic inheritance | doi=10.1090/S0273-0979-97-00712-X | mr=1414973 | year=1997 | journal=Bulletin of the American Mathematical Society |series=New Series | issn=0002-9904 | volume=34 | issue=2 | pages=107–130 | zbl=0876.17040 | doi-access=free }}
  • {{Citation | last1=Schafer | first1=Richard D. | title=Structure of genetic algebras | jstor=2372100 | mr=0027751 | year=1949 | journal=American Journal of Mathematics | issn=0002-9327 | volume=71 | issue=1 | pages=121–135 | doi=10.2307/2372100}}
  • {{Citation | last=Tian | first=Jianjun Paul | title=Evolution algebras and their applications | zbl=1136.17001 | series=Lecture Notes in Mathematics | volume=1921 | location=Berlin | publisher=Springer-Verlag | isbn=978-3-540-74283-8 | year=2008 }}
  • {{Citation | last1=Wörz-Busekros | first1=Angelika | title=Algebras in genetics | publisher=Springer-Verlag | location=Berlin, New York | series=Lecture Notes in Biomathematics | isbn=978-0-387-09978-1 | mr=599179 | year=1980 | volume=36}}
  • {{eom|title=Genetic algebra|first=A.|last= Wörz-Busekros}}

Further reading

  • {{citation | last=Lyubich | first=Yu.I. | title=Mathematical structures in population genetics. (Matematicheskie struktury v populyatsionnoj genetike) | language=Russian | zbl=0593.92011 | location=Kiev | publisher=Naukova Dumka | year=1983 }}

Category:Population genetics

Category:Non-associative algebras