Gerard Evan

{{Short description|British biologist}}

{{Use dmy dates|date=December 2013}}

{{Use British English|date=December 2013}}

{{Infobox scientist

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| birth_date = {{Birth date and age|df=yes|1955|08|17}}{{cite web |url=http://www.ukwhoswho.com/view/article/oupww/whoswho/U45197 |title=EVAN, Prof. Gerard Ian |work=Who's Who 2013, A & C Black, an imprint of Bloomsbury Publishing plc, 2013; online edn, Oxford University Press }}{{subscription required}}

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| fields = Cancer{{Cite journal

| last1 = Finch | first1 = A. J.

| last2 = Soucek | first2 = L.

| last3 = Junttila | first3 = M. R.

| last4 = Swigart | first4 = L. B.

| last5 = Evan | first5 = G. I.

| title = Acute Overexpression of Myc in Intestinal Epithelium Recapitulates Some but Not All the Changes Elicited by Wnt/ -Catenin Pathway Activation

| doi = 10.1128/MCB.01745-08

| journal = Molecular and Cellular Biology

| volume = 29

| issue = 19

| pages = 5306–5315

| year = 2009

| pmid = 19635809

| pmc =2747972

}}{{Cite journal

| last1 = Garcia | first1 = D.

| last2 = Warr | first2 = M. R.

| last3 = Martins | first3 = C. P.

| last4 = Brown Swigart | first4 = L.

| last5 = Passegue | first5 = E.

| last6 = Evan | first6 = G. I.

| doi = 10.1101/gad.16722111

| title = Validation of MdmX as a therapeutic target for reactivating p53 in tumors

| journal = Genes & Development

| volume = 25

| issue = 16

| pages = 1746–1757

| year = 2011

| pmid = 21852537

| pmc =3165938

}}{{Cite journal

| last1 = Murphy | first1 = D. J.

| last2 = Junttila | first2 = M. R.

| last3 = Pouyet | first3 = L.

| last4 = Karnezis | first4 = A.

| last5 = Shchors | first5 = K.

| last6 = Bui | first6 = D. A.

| last7 = Brown-Swigart | first7 = L.

| last8 = Johnson | first8 = L.

| last9 = Evan | first9 = G. I.

| doi = 10.1016/j.ccr.2008.10.018

| title = Distinct Thresholds Govern Myc's Biological Output in Vivo

| journal = Cancer Cell

| volume = 14

| issue = 6

| pages = 447–457

| year = 2008

| pmid = 19061836

| pmc =2723751

}}{{Cite journal

| last1 = Sodir | first1 = N. M.

| last2 = Swigart | first2 = L. B.

| last3 = Karnezis | first3 = A. N.

| last4 = Hanahan | first4 = D.

| last5 = Evan | first5 = G. I.

| last6 = Soucek | first6 = L.

| doi = 10.1101/gad.2038411

| title = Endogenous Myc maintains the tumor microenvironment

| journal = Genes & Development

| volume = 25

| issue = 9

| pages = 907–916

| year = 2011

| pmid = 21478273

| pmc =3084025

}}{{Cite journal | last1 = Kain | first1 = K. | title = The future of cancer therapy: An interview with Gerard Evan | doi = 10.1242/dmm.001396 | journal = Disease Models and Mechanisms | volume = 1 | issue = 2–3 | pages = 90–93 | year = 2008 | pmid = 19048069| pmc =2562192 }}{{Cite journal | author = Anon| doi = 10.1038/7213xiiia | title = Making the paper: Gerard Evan | journal = Nature | volume = 455 | issue = 7213 | pages = xiii | year = 2008 | s2cid = 4410691 | doi-access = free }}
Disease biology
Myc regulator gene{{Cite journal | last1 = Evan | first1 = G. | title = Taking a Back Door to Target Myc | doi = 10.1126/science.1217819 | journal = Science | volume = 335 | issue = 6066 | pages = 293–294 | year = 2012 | pmid = 22267799| bibcode = 2012Sci...335..293E | s2cid = 26445434 }}
p53 tumour suppressor{{Cite journal | last1 = Junttila | first1 = Melissa R. | last2 = Evan | first2 = Gerard I. | author-link2 = Gerard Evan| doi = 10.1038/nrc2728 | title = P53 — a Jack of all trades but master of none | journal = Nature Reviews Cancer | volume = 9 | issue = 11 | pages = 821–829 | year = 2009 | pmid = 19776747| s2cid = 29250930 }}

| workplaces = University of Oxford
University of Cambridge
UCSF
Cancer Research UK{{cite web|url=http://www.cancerresearchuk.org/science/research/who-and-what-we-fund/browse-by-location/cambridge/university-of-cambridge/gerard-evan-4750 |title=Gerard Evan : Cancer Research UK |archive-date=10 March 2014 |archive-url=https://web.archive.org/web/20140310024647/http://www.cancerresearchuk.org/science/research/who-and-what-we-fund/browse-by-location/cambridge/university-of-cambridge/gerard-evan-4750 |url-status=dead |df=dmy }}
Ensemble Therapeutics

| alma_mater = St Peter's College, Oxford
King's College, Cambridge

| thesis_title = Monoclonal antibodies as reagents for the analysis of cell surfaces

| thesis_url = http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.255332

| thesis_year = 1982

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| known_for = Disease Models & Mechanisms

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| awards = Fellow of the Royal Society (2004)
FMedSci (1999)http://www.acmedsci.ac.uk/p59fid5303.html {{Dead link|date=February 2022}}
PhD (1982)

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| website = {{URL|http://www.bioc.cam.ac.uk/uto/evan}}
{{URL|http://labmed.ucsf.edu/about/faculty/pathology-gevan.html}}

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Gerard Ian Evan FRS, FMedSci (born 17 August 1955) is a British biologist and, since May 2022, Professor of Cancer Biology at King's College London and a principal group leader in the Francis Crick Institute. Prior to this he was Sir William Dunn Professor of Biochemistry and Head of Biochemistry at the University of Cambridge (2009-2022).{{cite web|url=http://labmed.ucsf.edu/about/faculty/pathology-gevan.html |title=UCSF Departments of Pathology and Laboratory Medicine | About | Faculty | Gerard I. Evan, PhD, FRS, FMedSci |archive-date=1 June 2013 |archive-url=https://web.archive.org/web/20130601162425/http://labmed.ucsf.edu/about/faculty/pathology-gevan.html |url-status=dead |df=dmy }}{{AcademicSearch|10741614}}