Germacranolide

{{Short description|Type of natural chemical}}

File:Costunolide.svg, a prototypical germacranolide]]

Germacranolides are a group of natural chemical compounds classified as sesquiterpene lactones. They are found in a variety of plant species{{cite journal | author = Fraga, B. M. | title = Natural sesquiterpenoids | journal = Natural Product Reports | year = 1988 | volume = 5 | issue = 5 | pages = 497–521 | doi = 10.1039/np9880500497| url = https://digital.csic.es/bitstream/10261/12789/2/NPR-2007-24-1350.pdf }} and are known for their diverse and complex topology, as well as a wide array of pharmacological activities.{{Cite journal |last1=Patouret |first1=Rémi |last2=Cham |first2=Ning |last3=Chiba |first3=Shunsuke |date=2024-05-06 |title=Collective Synthesis of Highly Oxygenated (Furano)germacranolides Derived from Elephantopus mollis and Elephantopus tomentosus |url=https://pubmed.ncbi.nlm.nih.gov/38488804/ |journal=Angewandte Chemie International Edition in English |volume=63 |issue=19 |pages=e202402050 |doi=10.1002/anie.202402050 |issn=1521-3773 |pmid=38488804}}