German submarine U-161
{{italic title prefixed|16}}
U-161 may refer to one of the following German submarines:
- {{SMU|U-161}}, a Type U 93 submarine launched in 1918; served in World War I until surrendered on 20 November 1918; grounded on English east coast on way to be broken up, 1921
- {{GS|U-161|1941}}, a Type IXC submarine that served in World War II until sunk on 27 September 1943
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{{DEFAULTSORT:U-0161}}