Gordon Dougan

Dougan grew up on a council estate in Scunthorpe{{Cite tweet |last=Dougan |first=Gordon|user=GordonDougan1 |number=1522857454207483905 |title=I went to state school in Scunthorpe. Born on a council estate. A father at 20 years old. Now a professor in the Department of Medicine at Cambridge University and a Fellow of the Royal Society. Nothing was fair about getting there. If I am damaging Oxbridge, so be it}} and was educated at Henderson Avenue Junior School, Scunthorpe Grammar School and John Leggott College. He graduated with a degree in Biochemistry and received his PhD, both from the University of Sussex.{{cite thesis|degree=PhD|publisher=University of Sussex|url=|doi=|title=An Analysis of the Structure and Function of Plasmid Cole 1|first= Gordon|last=Dougan|date=1977|id={{EThOS|uk.bl.ethos.453881}}|website=|oclc=500427844|hdl=}}

After his PhD, Dougan completed postdoctoral research at the University of Washington (Seattle) in the laboratory of Professor Stanley Falkow. Dougan's research team studies enteric pathogens with a strong emphasis on basic pathogenic mechanisms and immunology.{{Cite journal | doi = 10.1126/science.1139253| title = Requirement of bic/microRNA-155 for Normal Immune Function| journal = Science| volume = 316| issue = 5824| pages = 608–11| year = 2007| last1 = Rodriguez | first1 = A.| last2 = Vigorito | first2 = E.| last3 = Clare | first3 = S.| last4 = Warren | first4 = M. V.| last5 = Couttet | first5 = P.| last6 = Soond | first6 = D. R.| last7 = Van Dongen | first7 = S.| last8 = Grocock | first8 = R. J.| last9 = Das | first9 = P. P.| last10 = Miska | first10 = E. A.| last11 = Vetrie | first11 = D.| last12 = Okkenhaug | first12 = K.| last13 = Enright | first13 = A. J.| last14 = Dougan | first14 = G.| last15 = Turner | first15 = M.| last16 = Bradley | first16 = A. | pmid=17463290 | pmc=2610435| bibcode = 2007Sci...316..608R}}{{Cite journal | doi = 10.1084/jem.20021345| title = CD4+CD25+ TR Cells Suppress Innate Immune Pathology Through Cytokine-dependent Mechanisms| journal = Journal of Experimental Medicine| volume = 197| pages = 111–9| year = 2002| last1 = Maloy | first1 = K. J.| last2 = Salaun | first2 = L.| last3 = Cahill | first3 = R.| last4 = Dougan | first4 = G.| last5 = Saunders | first5 = N. J.| last6 = Powrie | first6 = F. | pmid=12515818 | pmc=2193798 | issue=1}}{{Cite journal | doi = 10.1046/j.1365-2958.1998.01144.x| pmid = 9988469| title = Enteropathogenic and enterohaemorrhagic Escherichia coli: More subversive elements| journal = Molecular Microbiology| volume = 30| issue = 5| pages = 911–921| year = 1998| last1 = Frankel | first1 = G. | last2 = Phillips | first2 = A. D. | last3 = Rosenshine | first3 = I. | last4 = Dougan | first4 = G. | last5 = Kaper | first5 = J. B. | last6 = Knutton | first6 = S. | s2cid = 10781807| doi-access = free }}{{Scopus id}}{{Cite journal | doi = 10.1038/nature10392| title = Evidence for several waves of global transmission in the seventh cholera pandemic| journal = Nature| volume = 477| issue = 7365| pages = 462–465| year = 2011| last1 = Mutreja | first1 = A. | last2 = Kim | first2 = D. W. | last3 = Thomson | first3 = N. R. | last4 = Connor | first4 = T. R. | last5 = Lee | first5 = J. H. | last6 = Kariuki | first6 = S. | last7 = Croucher | first7 = N. J. | last8 = Choi | first8 = S. Y. | last9 = Harris | first9 = S. R. | last10 = Lebens | first10 = M. | last11 = Niyogi | first11 = S. K. | last12 = Kim | first12 = E. J. | last13 = Ramamurthy | first13 = T.| last14 = Chun | first14 = J. | last15 = Wood | first15 = J. L. N. | last16 = Clemens | first16 = J. D. | last17 = Czerkinsky | first17 = C. | last18 = Nair | first18 = G. B. | last19 = Holmgren | first19 = J. | last20 = Parkhill | first20 = J. | last21 = Dougan | first21 = G. | pmid=21866102 | pmc=3736323| bibcode = 2011Natur.477..462M}}{{Cite journal | doi = 10.1038/ng.2423| title = Intracontinental spread of human invasive Salmonella Typhimurium pathovariants in sub-Saharan Africa| journal = Nature Genetics| volume = 44| issue = 11| pages = 1215–1221| year = 2012| last1 = Okoro | first1 = C. K. | last2 = Kingsley | first2 = R. A. | last3 = Connor | first3 = T. R. | last4 = Harris | first4 = S. R. | last5 = Parry | first5 = C. M. | last6 = Al-Mashhadani | first6 = M. N. | last7 = Kariuki | first7 = S. | last8 = Msefula | first8 = C. L. | last9 = Gordon | first9 = M. A. | last10 = De Pinna | first10 = E. | last11 = Wain | first11 = J. | last12 = Heyderman | first12 = R. S. | last13 = Obaro | first13 = S. | last14 = Alonso | first14 = P. L. | last15 = Mandomando | first15 = I. | last16 = MacLennan | first16 = C. A. | last17 = Tapia | first17 = M. D. | last18 = Levine | first18 = M. M. | last19 = Tennant | first19 = S. M. | last20 = Parkhill | first20 = J. | last21 = Dougan | first21 = G. | pmid=23023330 | pmc=3491877}}{{Cite q|Q34082875}}{{Cite journal

| last1 = Achtman | first1 = M. | authorlink1 = Mark Achtman

| last2 = Wain | first2 = J.

| last3 = Weill | first3 = F. O. X.

| last4 = Nair | first4 = S.

| last5 = Zhou | first5 = Z.

| last6 = Sangal | first6 = V.

| last7 = Krauland | first7 = M. G.

| last8 = Hale | first8 = J. L.

| last9 = Harbottle | first9 = H.

| last10 = Uesbeck | first10 = A.

| last11 = Dougan | first11 = G. | authorlink11 = Gordon Dougan

| last12 = Harrison | first12 = L. H.

| last13 = Brisse | first13 = S.

| author14 = S. Enterica MLST Study Group

| editor1-last = Bessen

| editor1-first = Debra E

| title = Multilocus Sequence Typing as a Replacement for Serotyping in Salmonella enterica

| doi = 10.1371/journal.ppat.1002776

| journal = PLOS Pathogens

| volume = 8

| issue = 6

| pages = e1002776

| year = 2012

| pmid = 22737074

| pmc =3380943

| doi-access = free }} {{open access}}{{cite web|author=Anon |url=http://www.sanger.ac.uk/research/projects/microbialpathogenesis/ |title=Microbial pathogenesis – Wellcome Trust Sanger Institute |publisher=Sanger.ac.uk |date=30 January 2013 |access-date=2013-06-06}} He has a particular interest in using genomics to study host/pathogens interactions, in particular using Salmonella enterica serovar Typhi, the cause of typhoid. He has extensive experience working both in industry and in academia. Before moving to the WTSI he was the Director of the Centre for Molecular Microbiology and Infection at the Imperial College London and a Professor of Physiological Biochemistry. There he was responsible for securing multimillion-pound funding for a new building in Kensington and providing infrastructure for the science.

Throughout his career Dougan has served as a referee, advisor and consultant for numerous institutions, universities, boards, committees and other organisations. He was a trustee of the International Vaccine Institute in Korea and has worked with other global agencies including the World Health Organization and the Global Alliance for Vaccine and Innovations (now GAVI Alliance).

Dougan was a lecturer in the Moyne Institute in Trinity College, Dublin{{citation needed|date=June 2015}} and then worked for over ten years in industry developing vaccines and novel drugs at the Wellcome Foundation (now GlaxoSmithKline GSK). He has participated in early and late clinical studies on several vaccines and is an expert in vaccinology/pathogenic mechanisms, specialising on the immunology of mucosal vaccines and molecular basis of infection. He has been Chair of the Novartis Vaccines & Diagnostics Scientific Advisory Board and has spun out a number of companies. He has published over 400 research papers, edited several books and has sat on the editorial boards of prestigious journals.{{cite web|url=https://pubmed.ncbi.nlm.nih.gov/?term=Gordon+Dougan |title=Gordon Dougan – PubMed – NCBI |publisher=Ncbi.nlm.nih.gov |date=25 March 2013 |access-date=2013-06-06}}

Dougan was elected a Fellow of the Royal Society in 2012. His nomination reads: {{centred pull quote|Gordon Dougan is distinguished through his investigations into how bacteria interact with and stimulate the mucosal surfaces of the body during infection. His work has focused on bacterial pathogens, principally Salmonella Typhi and other enteric bacteria and has exploited genetic manipulation of both the host and pathogen. He has made important contributions to basic studies on the molecular basis of the infection process, genomics and to the development of practical vaccines.{{Cite web | url=https://royalsociety.org/people/gordon-dougan-11353/ | title=Gordon Dougan|publisher=Royal Society|website=royalsociety.org}}}}

Dougan was elected a member of the European Molecular Biology Organization (EMBO) in 2011. He was elected a Fellow of the Academy of Medical Sciences (FMedSci) in 2002.{{cite web|url=http://www.acmedsci.ac.uk/p59.html |title=The Academy of Medical Sciences | Directory of Fellows |publisher=Acmedsci.ac.uk |access-date=2013-06-06}}{{cite web|url=http://royalsociety.org/about-us/fellowship/fellows/ |title=Fellows of the |publisher=Royal Society |access-date=2013-06-06}}

Dougan has been a lifelong supporter of Scunthorpe United{{fact|date=May 2022}} and is an experienced beekeeper.{{cite tweet |user=GordonDougan1 |number=1348207648878055425 |first=Gordon|last= Dougan |title=As an experienced beekeeper I am dismayed but not surprised that the UK-Gov wants to bring back neonicotinoid insecticides. Hive survival is always a delicate balance. Give bees a chance!}}

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Category:Year of birth missing (living people)

Category:Living people

Category:People from Scunthorpe

Category:Alumni of the University of Sussex

Category:British microbiologists

Category:Members of the European Molecular Biology Organization

Category:Fellows of the Royal Society

Category:Fellows of Wolfson College, Cambridge