HLA-DR8

The serological reaction of DR8 is relatively good. The serology of DRB1*0808, *0809 and *0813 to *0832 serotypes is unknown.

DR8 is linked to papillary thyroid carcinomas,{{cite journal |vauthors=Porto T, Coelho I, Boavida J, Pereira C, Nunes J, Mendonça D, Martins B, Sobrinho L, Leite V | title = Association of HLA DQ4-DR8 haplotype with papillary thyroid carcinomas. | journal = Clin Endocrinol | volume = 64 | issue = 2 | pages = 179–83 | year = 2006 | pmid = 16430717 | doi = 10.1111/j.1365-2265.2006.02445.x| s2cid = 22695710 }} early onset pauciarticular juvenile chronic arthritis,{{cite journal |vauthors=Haas J, Truckenbrodt H, Paul C, Hoza J, Scholz S, Albert E | title = Subtypes of HLA-DRB1*03, *08, *11, *12, *13 and *14 in early onset pauciarticular juvenile chronic arthritis (EOPA) with and without iridocyclitis. | journal = Clin Exp Rheumatol | volume = 12 | pages = S7–14 | year = 1994| issue = Suppl 10 | pmid = 7955632}}{{cite journal |vauthors=Säilä H, Pitkäniemi J, Tuomilehto J, Savolainen A, Alakulppi N, Tuomilehto-Wolf E, Leirisalo-Repo M, Aho K | title = HLA and susceptibility to juvenile idiopathic arthritis: a study of affected sibpairs in an isolated Finnish population. | journal = J Rheumatol | volume = 31 | issue = 11 | pages = 2281–5 | year = 2004 | pmid = 15517645}} primary biliary cirrhosis{{cite journal |vauthors=Underhill J, Donaldson P, Bray G, Doherty D, Portmann B, Williams R | title = Susceptibility to primary biliary cirrhosis is associated with the HLA-DR8-DQB1*0402 haplotype. | journal = Hepatology | volume = 16 | issue = 6 | pages = 1404–8 | year = 1992 | pmid = 1359995 | doi = 10.1002/hep.1840160616| s2cid = 7200339 | doi-access = free }}

HLA-DRB1*0801 is linked to primary biliary cirrhosis{{cite journal |vauthors=Charatcharoenwitthaya P, Lindor K | title = Current concepts in the pathogenesis of primary biliary cirrhosis. | journal = Ann Hepatol | volume = 4 | issue = 3 | pages = 161–75 | year = 2005| doi = 10.1016/S1665-2681(19)32061-7 | pmid = 16177655| doi-access = free }} In Mexicans DR8 is found more often in type-2 juvenile diabetes.{{cite journal |vauthors=Rodríguez-Ventura AL, Yamamoto-Furusho JK, Coyote N, etal | title = HLA-DRB1*08 allele may help to distinguish between type 1 diabetes mellitus and type 2 diabetes mellitus in Mexican children | journal = Pediatric Diabetes | volume = 8 | issue = 1 | pages = 5–10 | year = 2007 | pmid = 17341285 | doi = 10.1111/j.1399-5448.2006.00221.x| s2cid = 35352151 | doi-access = free }}

HLA-DRB1*0803 is also linked to primary biliary cirrhosis

HLA-DR8 is not genetically linked to HLA-DR51 to DR53, but is linked to DQ4 serotypes.

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{{DR serotypes}}

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