HMB

• β-Hydroxy β-methylbutyric acid, {{chem|(CH|3|)|2|C(OH)|CH|2|COOH}}, a metabolite of the essential amino acid leucine, synthesized in the human body
• Human Melanoma Black, a monoclonal antibody

• Humburi Senni language, spoken in Burkina Faso and Mali

• Half Moon Bay, California, city in the United States

• Historical medieval battles, a modern sport

• Hawkeye Marching Band, the marching band for the University of Iowa
• Hukbong Mapagpalaya ng Bayan, the new name used by the Hukbalahap in their later rebellion against the Third Philippine Republic
• HabibMetro, a Swiss multinational bank in Pakistan
• Heavy menstrual bleeding, a menstrual condition
• Host Memory Buffer, an optional feature in version 1.2 of the NVMe specification, which allows SSDs to utilize the DRAM of the host machine
• His/Her Magesty's Barque

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